Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Yves R Boisclair"'
Autor:
Cassandra L. Lamb, Sarah L. Giesy, Molly M. McGuckin, James W. Perfield, Anthony Butterfield, Mohammed Moniruzzaman, Norman J. Haughey, Joseph W. McFadden, Yves R. Boisclair
Publikováno v:
Am J Physiol Regul Integr Comp Physiol
During metabolically demanding physiological states, ruminants and other mammals coordinate nutrient use among tissues by varying the set point of insulin action. This set point is regulated in part by metabolic hormones with some antagonizing (e.g.,
Publikováno v:
In The Journal of Nutrition December 2013 143(12):1913-1919
Autor:
Xiaoqin Yang, Qingqing Liu, Guangyu Long, Yabing Hu, Yves R. Boisclair, Zhenglong Gu, Qiaoming Long
Publikováno v:
The Journal of Biological Chemistry
Mitochondrial dysfunction is associated with a variety of human diseases including neurodegeneration, diabetes, nonalcohol fatty liver disease (NAFLD), and cancer, but its underlying causes are incompletely understood. Using the human hepatic cell li
Autor:
Sarah L. Giesy, Yves R. Boisclair, Helga Sauerwein, Christopher Steven Krumm, B.L. Moore, Luciano Caixeta, J.W. Perfield nd
Publikováno v:
Journal of Dairy Science. 102:11586-11596
Modern dairy cows rely on hormonally driven mechanisms to coordinate the metabolic adaptations needed to meet the energy and nutrient deficits of early lactation. In the case of glucose, dairy cows cope with its scarcity during early lactation via re
Autor:
Qiongge Tian, Ke-Yu Deng, Rajni Singh, Yves R. Boisclair, Qingqing Liu, Yuanyuan Gao, Zhixiong Pan, Qiaoming Long, Yi Gong, Manman Zhang, Yabing Hu
Publikováno v:
Diabetes. 68:733-746
The molecular underpinnings of β-cell dysfunction and death leading to diabetes are not fully elucidated. The objective of the current study was to investigate the role of endoplasmic reticulum–associated degradation (ERAD) in pancreatic β-cells.
Publikováno v:
J Anim Sci
Intrauterine growth restriction (IUGR) is often observed in one of the fetuses carried by well-fed prolific ewes. This condition is the result of an insufficient placental size to cover the nutritional needs of the fetus during the near exponential g
Autor:
Guangyu Long, Yves R. Boisclair, Zhenglong Gu, Xiaoqing Yang, Qiaoming Long, Qingqing Liu, Yabin Hu
Mitochondrial dysfunction has been associated with a variety of human diseases including neurodegeneration, diabetes, non-alcohol fatty liver disease (NAFLD) and cancer, but its underlying causes are incompletely understood. Endoplasmic reticular ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d09c59f2ec49c56a725cbbfcc689ae28
Publikováno v:
The Journal of Nutrition. 148:1529-1535
Background Increased plasma free fatty acids (FFAs) impair insulin sensitivity in dairy cows via unknown mechanisms. In nonruminants, saturated FFAs upregulate the hepatic synthesis and secretion of ceramide, which inhibits insulin action. Objective
Publikováno v:
Journal of Dairy Science. 101:7585-7592
Trans-10,cis-12 conjugated linoleic acid (CLA) has been identified as an intermediate of rumen fatty acid biohydrogenation that caused milk fat depression (MFD) in the dairy cow. Previous studies in cows experiencing CLA- and diet-induced MFD have id
Autor:
Katie M. Schoenberg, Luciano Caixeta, Sarah L. Giesy, Donald C. Beitz, Yves R. Boisclair, Christopher Steven Krumm, James W. Perfield nd, Anthony M. Butterfield
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 313:R526-R534
Modern dairy cows meet the energy demand of early lactation by calling on hormonally driven mechanisms to increase the use of lipid reserves. In this context, we recently reported that fibroblast growth factor-21 (FGF21), a hormone required for effic