Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Yves Lobet"'
Autor:
Peter Probst, Steven G. Reed, Joe Cohen, Pascal Mettens, Yves Lobet, Ajay Bhatia, Hang Fang, Pamela J. Ovendale, Rhea N. Coler, Brenda Barth, Jean-Francois Maisonneuve, Mark R. Alderson
Publikováno v:
FEMS Immunology & Medical Microbiology. 55:258-270
Chlamydia trachomatis infection is the most common sexually transmitted bacterial infection worldwide, with over 91 million cases estimated annually. An effective subunit vaccine against Chlamydia may require a multivalent subunit cocktail of antigen
Autor:
Steven G, Reed, Rhea N, Coler, Wilfried, Dalemans, Wilifred, Dalemans, Esterlina V, Tan, Eduardo C, DeLa Cruz, Randall J, Basaraba, Ian M, Orme, Yasir A W, Skeiky, Mark R, Alderson, Karen D, Cowgill, Jean-Paul, Prieels, Rodolfo M, Abalos, Marie-Claude, Dubois, Joe, Cohen, Pascal, Mettens, Yves, Lobet
Publikováno v:
Proceedings of the National Academy of Sciences. 106:2301-2306
The development of a vaccine for tuberculosis requires a combination of antigens and adjuvants capable of inducing appropriate and long-lasting T cell immunity. We evaluated Mtb72F formulated in AS02A in the cynomolgus monkey model. The vaccine was i
Autor:
Antonio Campos-Neto, Steven G. Reed, Mark R. Alderson, Pamela J. Ovendale, Yasir A. W. Skeiky, Yves Lobet, Ian M. Orme, Wilfried Dalemans
Publikováno v:
Vaccine. 23:3937-3945
MTB41 is a Mycobacterium antigen that is recognized by CD4+ T cells early after experimental infection of mice with Mycobacterium tuberculosis and by PBMC from healthy PPD positive individuals. Immunization of mice with plasmid DNA encoding the MTB41
Autor:
Nilu Goonetilleke, Andrzej Pawlowski, Kim A. Hatch, Graham J. Hatch, Peter Andersen, T. Mark Doherty, Ann Williams, Wilfried Dalemans, Helen McShane, Karen E. Gooch, Kris Huygen, Stefan H. E. Kaufmann, Karen Blake, Douglas B. Lowrie, Stewart T. Cole, Philip Marsh, Tanya Parish, Simon O. Clark, Alexander S. Pym, Joe Cohen, Gunilla Källenius, Priscille Brodin, Carlos Martin, Brigitte Gicquel, Kees L. M. C. Franken, Stefan B. Svenson, Yves Lobet, Debbie A. Smith, Peter Seiler, Graham Hall, Neil G. Stoker, Adrian V. S. Hill, Leander Grode, Tom H. M. Ottenhoff
Publikováno v:
Tuberculosis. 85:29-38
The TB Vaccine Cluster project funded by the EU Fifth Framework programme aims to provide novel vaccines against tuberculosis that are suitable for evaluation in humans. This paper describes the studies of the protective efficacy of vaccines in a gui
Autor:
Steven G. Reed, Skeiky Yasir A W, Oliver C. Turner, Lise Brandt, Philip L. Chapman, Todd M. Lasco, Mark R. Alderson, Wilfried Dalemans, Angelo Izzo, Ian M. Orme, Yves Lobet, Randall J. Basaraba
Publikováno v:
Infection and Immunity. 72:6622-6632
A tuberculosis vaccine candidate consisting of a 72-kDa polyprotein or fusion protein based upon the Mtb32 and Mtb39 antigens of Mycobacterium tuberculosis and designated Mtb72F was tested for its protective capacity as a potential adjunct to the Myc
Autor:
Pierre Smithkline Beecham Bio. Hauser, M. Comberbach, D. Fu, Pierre Desmons, Yves Lobet, Pierre Voet, D. De Grave, E. Lebacq, C. Van Hoecke
Publikováno v:
Vaccine. 14:1620-1626
The safety, reactogenicity and immunogenicity of three candidate Lyme vaccines based on recombinant outer surface protein (OspA) presented in either lipidated or unlipidated forms, were assessed in 300 seronegative volunteers. Subjects received three
Publikováno v:
DNA Sequence. 5:251-254
The nucleotide sequence encoding the Outer Surface Protein A (OspA) from two Borrelia burgdorferi sensu lato isolates, G25 and VS461, has been determined. On the basis of a phylogenetic analysis, strains G25 and VS461 were respectively assigned to th
Autor:
Joseph Piesman, Yves Lobet, Thomas R. Burkot, William T. Golde, Guy Dequesne, Marc C. Dolan, Pierre Hauser, Carine Capiau
Publikováno v:
Vaccine. 13:435-441
Development of a vaccine for the Lyme disease spirochete, Borrelia burgdorferi, has focused on the bacterial lipoprotein, major outer surface protein A (OspA). With few exceptions, testing of OspA vaccines in animal models has involved challenge with
Autor:
Gail B. Plauché, Lisa C. Bowers, Yves Lobet, Jeanette E. Purcell, Philippe Denoël, Mario T. Philipp
Publikováno v:
Journal of Clinical Microbiology. 40:4340-4342
The nasopharyngeal bacterial flora of healthy rhesus macaques was surveyed for the presence of Neisseria and Haemophilus species, as well as Moraxella catarrhalis . M. catarrhalis was found both in healthy rhesus macaques and in possibly immunocompro
Autor:
Etienne Simoen, Camille Locht, Guy Dequesne, Christiane SmithKline Beecham Feron, Pierre Hauser, Yves Lobet
Publikováno v:
The Journal of Experimental Medicine
Pertussis toxin plays a major role in the pathogenesis of whooping cough and is considered an important constituent of vaccines against this disease. It is composed of five different subunits associated in a molar ratio 1S1:1S2:1S3:2S4:1S5. The S1 su