Zobrazeno 1 - 10
of 176
pro vyhledávání: '"Yves Humblet"'
Autor:
Jacques De Grève, Jan Van Meerbeeck, Johan F Vansteenkiste, Lore Decoster, Anne-Pascale Meert, Peter Vuylsteke, Christian Focan, Jean-Luc Canon, Yves Humblet, Guy Berchem, Benoit Colinet, Danny Galdermans, Lionel Bosquée, Joanna Vermeij, Alex Dewaele, Caroline Geers, Denis Schallier, Erik Teugels
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0147599 (2016)
INTRODUCTION:Epidermal Growth Factor Receptor (EGFR) tyrosine kinase inhibition is the preferred first-line treatment of advanced adenocarcinoma of the lung that harbors EGFR activating tyrosine kinase domain mutations. Most data available pertain to
Externí odkaz:
https://doaj.org/article/d77d90c2874a41ca9219fe0d09d1012a
Autor:
Eric Van Cutsem, Fatima Rangwala, Bijoyesh Mookerjee, Severine Bettinger, Savina Jaeger, Jan C. Brase, A. Scott Jung, Filip De Vos, Yves Humblet, Peter J. O'Dwyer, Rona Yaeger, Josep Tabernero, Michael S. Gordon, Kei Muro, Gary Middleton, Salvatore Siena, Autumn J. McRee, Antoine Hollebecque, Johanna C. Bendell, Takayuki Yoshino, Jan H.M. Schellens, Chloe E. Atreya, Thierry André, Ryan B. Corcoran
Supplementary Material
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14f6fb2e504ae1680a06b6c46245d1e1
https://doi.org/10.1158/2159-8290.22532668.v1
https://doi.org/10.1158/2159-8290.22532668.v1
Autor:
Scott D. Patterson, David Reese, Jeffrey Wiezorek, Thierry André, Jean-Luc Van Laethem, Yves Humblet, Jing Huang, Eric Van Cutsem, Salvatore Siena, Alex Parker, Kelly S. Oliner, Marc Peeters
PDF file - 109K, PCR Primer Sequences; Baseline Demographic and Clinical Characteristics for Patients With and Without Available Multigene Information; Mutations Identified In Available Patient Tumor Specimens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76ecd9ef922fbf1a547d477d563ad392
https://doi.org/10.1158/1078-0432.22455416
https://doi.org/10.1158/1078-0432.22455416
Autor:
Scott D. Patterson, David Reese, Jeffrey Wiezorek, Thierry André, Jean-Luc Van Laethem, Yves Humblet, Jing Huang, Eric Van Cutsem, Salvatore Siena, Alex Parker, Kelly S. Oliner, Marc Peeters
Purpose: To investigate whether EGF receptor (EGFR) pathway mutations predicted response to monotherapy with panitumumab, an anti-EGFR monoclonal antibody, in a randomized phase III study of metastatic colorectal cancer.Experimental Design: Using mas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8c6055249aef2ac2764ad300f3fc0db
https://doi.org/10.1158/1078-0432.c.6523025.v1
https://doi.org/10.1158/1078-0432.c.6523025.v1
Autor:
Sabine Tejpar, Eric Van Cutsem, Yves Humblet, Marc Peeters, Jean-Luc Van Laethem, Maria Debiec-Rychter, An Capoen, Wendy De Roock, Bart Biesmans, Jef De Schutter, Gert De Hertogh, Hubert Piessevaux, Steffen Fieuws, Nicola Personeni
Supplementary Tables S1-S4 from Clinical Usefulness of EGFR Gene Copy Number as a Predictive Marker in Colorectal Cancer Patients Treated with Cetuximab: A Fluorescent In situ Hybridization Study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22edfb37b09a7e2f7904867ac454a78d
https://doi.org/10.1158/1078-0432.22439388
https://doi.org/10.1158/1078-0432.22439388
Autor:
Scott D. Patterson, David Reese, Jeffrey Wiezorek, Thierry André, Jean-Luc Van Laethem, Yves Humblet, Jing Huang, Eric Van Cutsem, Salvatore Siena, Alex Parker, Kelly S. Oliner, Marc Peeters
PDF file - 57K, Summary of tumor response and tumor genotype among patients who received treatment with panitumuab plus BSC or BSC alone in either the randomized phase 3 study or the extension and who had multigene sequencing information available. F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::672db1141356854819990cf18cb1d3a2
https://doi.org/10.1158/1078-0432.22455419
https://doi.org/10.1158/1078-0432.22455419
Autor:
Sabine Tejpar, Eric Van Cutsem, Yves Humblet, Marc Peeters, Jean-Luc Van Laethem, Maria Debiec-Rychter, An Capoen, Wendy De Roock, Bart Biesmans, Jef De Schutter, Gert De Hertogh, Hubert Piessevaux, Steffen Fieuws, Nicola Personeni
Purpose: To evaluate the usefulness and the pitfalls inherent to the assessment of the epidermal growth factor receptor (EGFR) gene copy number (GCN) by fluorescence in situ hybridization (FISH) for outcome prediction to cetuximab in metastatic color
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::882b72fe4a8d56e4db87d6183935c3c2
https://doi.org/10.1158/1078-0432.c.6516861.v1
https://doi.org/10.1158/1078-0432.c.6516861.v1
Publikováno v:
Histopathology, Vol. 72, no. 4, p. 707-710 (2018)
Rearrangement of the ALK gene and overexpression of ALK seems to occur very rarely in neuroendocrine lung tumors, with only 3 cases of atypical carcinoid and 1 large cell neuroendocrine carcinoma (LCNEC) reported in detail until now.1,2,3,4 Here, we
Autor:
Alex Kartheuser, Etienne Danse, Daniel Léonard, A Medina Benites, M. Van den Eynde, Yves Humblet, N. Abbes Orabi, Anne Jouret-Mourin, Daphné Debetancourt, A. van Maanen, C. Remue, JC De Schoutheete, Ch Sempoux, F. Maddalena, A Dragean, Pierre Scalliet
Publikováno v:
Colorectal Disease. 18:O175-O184
AIM Nodal stage is a strong prognostic factor of oncological outcome of rectal cancer. To compensate for the variation in total number of harvested nodes, calculation of the lymph node ratio (LNR) has been advocated. The aim of the study was to compa
Autor:
Gabriela Bindea, Lucie Lafontaine, Yves Humblet, Anne Jouret-Mourin, Najeeb Syed, Catherine Hubert, Alex Kartheuser, Mihaela Angelova, Daniela Bruni, Jérôme Galon, Michele Ceccarelli, Davide Bedognetti, Marc Van den Eynde, Bénédicte Buttard, Bernhard Mlecnik, Angela Vasaturo, Francesco M. Marincola, Erwan Morgand, Tessa Fredriksen
Publikováno v:
Cell. 175(3)
We examined how the immune microenvironment molds tumor evolution at different metastatic organs in a longitudinal dataset of colorectal cancer. Through multiplexed analyses, we showed that clonal evolution patterns during metastatic progression depe