Zobrazeno 1 - 10 of 108 pro vyhledávání: '"Yves Claude Guillaume"'
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Immobilization of the SARS-CoV-2-receptor binding domain onto methacrylate-based monoliths for nano LC at 30 nL min−1 and application for research of its ligands
Autor: Yves Claude Guillaume, Claire André
Publikováno v: Analytical Methods. 14:156-164
For the design of novel potent molecules against therapeutic protein targets produced in a low quantity or that are very expensive, the development of miniaturized analytical techniques is of crucial importance.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4ef57d9416230896f4ce91fd814ac432
https://doi.org/10.1039/d1ay01913a
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4
An organic monolithic capillary column functionalized with human serum albumin and its application for the nano – chromatography study of its binding with universal cancer peptides and its impact on immunogenicity
Autor: Andre Claire, Lydie Lethier, Yves Claude Guillaume
Publikováno v: Journal of Liquid Chromatography & Related Technologies. 43:777-783
Sixty picomoles of human serum albumin (HSA) was immobilized on a glycidylmethacrylate (GMA) capillary column previously developed by our group to study its binding with two universal cancer peptid...
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0df33d1420b665ebcad1909436e79145
https://doi.org/10.1080/10826076.2020.1811727
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5
Immobilization of the SARS-CoV-2-receptor binding domain onto methacrylate-based monoliths for nano LC at 30 nL min
Autor: Yves Claude, Guillaume, Claire, André
Publikováno v: Analytical methods : advancing methods and applications. 14(2)
For the design of novel potent molecules against therapeutic protein targets produced in a low quantity or that are very expensive, the development of miniaturized analytical techniques is of crucial importance. One challenging target is the receptor
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e27ed623bd36da20ebc335ec53f3a8a4
https://pubmed.ncbi.nlm.nih.gov/34927183
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6
Development of nano affinity columns for the study of ligand (including SARS-CoV-2 related proteins) binding to heparan sulfate proteoglycans
Autor: Yves Claude Guillaume, Claire André
Publikováno v: Analytical methods : advancing methods and applications. 13(27)
The interactions of heparan sulfate proteoglycans (HSPGs) present on the cell surface with target proteins lead to cell signaling and they are considered as viral receptors. The analysis of the recognition mechanism between HSPG and its potential lig
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98f989e49bc4c3e6b70d6304bb90c8e4
https://pubmed.ncbi.nlm.nih.gov/34132262
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Thermodynamics of the association of transthyretin and its nanovectorized form with heparan sulfate proteoglycan HPLC stationary phase and correlation with tetramer stability and amyloidogenicity
Autor: Yves Claude Guillaume, Lydie Lethier, Andre Claire
Publikováno v: Journal of Liquid Chromatography & Related Technologies. 43:1-9
As transthyretin (TTR) can prevent Aβ aggregation, a key protein in Alzheimer disease (AD), we developed a novel nanovector based on single wall carbon nanotubes (SWCNTs) functionalized by ...
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f1bd3a70dc2c024783e8036d9ff41b73
https://doi.org/10.1080/10826076.2018.1489283
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8
Development of a new nano arginase HPLC capillary column for the fast screening of arginase inhibitors and evaluation of their binding affinity
Autor: Claire André, Yves Claude Guillaume
Publikováno v: Journal of Chromatography B. 1175:122751
A simple and rapid Nano LC method has been developed for the screening of arginase inhibitors. The method is based on the immobilization of biotinylated arginase on a neutravidin functionalized nano HPLC capillary column. The arginase immobilization
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::698b98fa76bdbb71a6dd5a390ab0e71d
https://doi.org/10.1016/j.jchromb.2021.122751
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9
Development of a simple technique for the coating of monolithic silica with pristine boron nitride nanotubes (BNNTs): HPLC chromatographic applications
Autor: Yves Claude Guillaume, Claire André
Publikováno v: Talanta. 164:39-44
In this paper, a novel and very simple homogeneous coating of a monolithic silica HPLC support using pristine boron nitride nanotubes (BNNTs) was d0.escribed. The chromatographic support was coated with BNNTs in a non covalent way to preserve the nan
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83c455b5a3139d885fe4da899696c051
https://doi.org/10.1016/j.talanta.2016.10.105
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10
Enhanced DR5 binding capacity of nanovectorized TRAIL compared to its cytotoxic version by affinity chromatography and molecular docking studies
Autor: Guillaume Herlem, Tijani Gharbi, Al Batoul Zakaria, Yves Claude Guillaume, Olivier Micheau, Fabien Picaud
Publikováno v: Journal of Molecular Recognition. 29:406-414
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induces apoptosis of cancer cells when bound to its cognate receptors, TRAIL-R1 and TRAIL-R2 (DR4 and DR5), without being toxic to healthy cells. Nanovectorized TRAIL (abbreviated as NPT
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5ac98dcde93932ab4369e039bd68e262
https://doi.org/10.1002/jmr.2539
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