Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Yves Cambet"'
Autor:
Audrey Roussel-Gervais, Stéphanie Sgroi, Yves Cambet, Sylvain Lemeille, Tamara Seredenina, Karl-Heinz Krause, Vincent Jaquet
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
The tropomyosin receptor kinase B (TrkB) is encoded by the NTRK2 gene. It belongs to the family of transmembrane tyrosine kinases, which have key roles in the development and maintenance of the nervous system. Brain-derived neurotrophic factor (BDNF)
Externí odkaz:
https://doaj.org/article/5490a6c7719248d6b37acd6f28691abb
Autor:
Lydia Wehrli, Ioannis Galdadas, Lionel Voirol, Martin Smieško, Yves Cambet, Vincent Jaquet, Stéphane Guerrier, Francesco Luigi Gervasio, Serge Nef, Rita Rahban
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
The sperm-specific channel CatSper (cation channel of sperm) controls the intracellular Ca2+ concentration ([Ca2+]i) and plays an essential role in sperm function. It is mainly activated by the steroid progesterone (P4) but is also promiscuously acti
Externí odkaz:
https://doaj.org/article/615465c0b9f74934804518fb5b8517a1
Autor:
Aleksandra Malgorzata Siedlar, Tamara Seredenina, Anna Faivre, Yves Cambet, Marie-José Stasia, Dominik André-Lévigne, Marie-Luce Bochaton-Piallat, Brigitte Pittet-Cuénod, Sophie de Seigneux, Karl-Heinz Krause, Ali Modarressi, Vincent Jaquet
Publikováno v:
Redox Biology, Vol 60, Iss , Pp 102609- (2023)
Differentiation of fibroblasts to myofibroblasts is governed by the transforming growth factor beta (TGF-β) through a mechanism involving redox signaling and generation of reactive oxygen species (ROS). Myofibroblasts synthesize proteins of the extr
Externí odkaz:
https://doaj.org/article/507fecb164a84209b10ef09ff4779ba1
Autor:
Eirini D. Tseligka, Stéphanie Conzelmann, Yves Cambet, Tifany Schaer, Francesco Negro, Sophie Clément
Publikováno v:
JHEP Reports, Vol 5, Iss 3, Pp 100652- (2023)
Background & Aims: Chronic hepatitis delta is the most severe form of chronic viral hepatitis and is associated with faster progression towards cirrhosis, liver decompensation, and hepatocellular carcinoma. Hepatitis delta virus (HDV)’s tight depen
Externí odkaz:
https://doaj.org/article/fb46edd353b54a17a55d7c7a57760a8f
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2023)
The nicotinamide adenine dinucleotide phosphate oxidase 2 (NOX2) multi-subunit complex is a highly abundant and central source of reactive oxygen species. NOX2 is a key enzyme of the innate immune system involved in antibacterial response, but excess
Externí odkaz:
https://doaj.org/article/f9b8d6e14aa445c6a29b64a5e4ff07b9
Autor:
Olivier Preynat-Seauve, Evelyne Bao-Vi Nguyen, Yvonne Westermaier, Margaux Héritier, Sébastien Tardy, Yves Cambet, Maxime Feyeux, Aurélie Caillon, Leonardo Scapozza, Karl-Heinz Krause
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Phenazopyridine is a widely used drug against urinary tract pain. The compound has also been shown to enhance neural differentiation of pluripotent stem cells. However, its mechanism of action is not understood. Based on its chemical structure, we hy
Externí odkaz:
https://doaj.org/article/0b714db4ddf34294a62575c214553ec6
Autor:
Astrid Malézieux-Picard, Fabien Abdul, François R. Herrmann, Aurélie Caillon, Pascale Ribaux, Yves Cambet, Sabine Yerly, Stéphanie Baggio, Nathalie Vernaz, Dina Zekry, Karl-Heinz Krause, Olivier Preynat-Seauve, Virginie Prendki
Publikováno v:
Diagnostics, Vol 12, Iss 8, p 1813 (2022)
Background: The SARS-CoV-2 pandemic was particularly devastating for elderly people, and the underlying mechanisms of the disease are still poorly understood. In this study, we investigated fusion inhibitory antibodies (fiAbs) in elderly and younger
Externí odkaz:
https://doaj.org/article/98d9085aa0194d1aaa7178e5f9d803a5
Autor:
Myriam Roth, Vincent Jaquet, Sylvain Lemeille, Eve-Julie Bonetti, Yves Cambet, Patrice François, Karl-Heinz Krause
Publikováno v:
Antioxidants, Vol 11, Iss 4, p 655 (2022)
Hydrogen peroxide (H2O2) is a key defense component of host-microbe interaction. However, H2O2 concentrations generated by immune cells or epithelia are usually insufficient for bacterial killing and rather modulate bacterial responses. Here, we inve
Externí odkaz:
https://doaj.org/article/e636196abce44a29a781b5a7b77c4f87
Redox activation of excitatory pathways in auditory neurons as mechanism of age-related hearing loss
Autor:
Francis Rousset, German Nacher-Soler, Marta Coelho, Sten Ilmjarv, Vivianne Beatrix Christina Kokje, Antoine Marteyn, Yves Cambet, Michael Perny, Marta Roccio, Vincent Jaquet, Pascal Senn, Karl Heinz Krause
Publikováno v:
Redox Biology, Vol 30, Iss , Pp - (2020)
Age-related hearing (ARHL) loss affects a large part of the human population with a major impact on our aging societies. Yet, underlying mechanisms are not understood, and no validated therapy or prevention exists. NADPH oxidases (NOX), are important
Externí odkaz:
https://doaj.org/article/7acaa3de12cc454c88aa37a7e2e37b3e
Autor:
Krause, Myriam Roth, Vincent Jaquet, Sylvain Lemeille, Eve-Julie Bonetti, Yves Cambet, Patrice François, Karl-Heinz
Publikováno v:
Antioxidants; Volume 11; Issue 4; Pages: 655
Hydrogen peroxide (H2O2) is a key defense component of host-microbe interaction. However, H2O2 concentrations generated by immune cells or epithelia are usually insufficient for bacterial killing and rather modulate bacterial responses. Here, we inve