Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Yves Baumlin"'
Publikováno v:
Transplantation. 78:345-351
Background We recently demonstrated that donor medial cells are replaced by smooth muscle alpha-actin (SMA)-expressing host cells in murine carotid allografts. In this study, we investigated neointimal cell dynamics including effects of cyclosporine
Publikováno v:
Transplantation. 76:1166-1170
Background Apolipoprotein E-deficient (apoE-/-) mice spontaneously develop hypercholesterolemia and atherosclerotic lesions. This may be an appropriate background for the development of graft vessel disease. The authors therefore investigated the eff
Publikováno v:
Transplant Immunology. 9:43-49
Objective: The macrolide immunosuppressant RAD and the immunomodulator FTY720 have distinct mechanisms of action. We investigated the efficacy of RAD (everolimus, certican®) alone or in combination with FTY720 on graft survival (GS) and histology in
Publikováno v:
Transplantation. 72:168-171
Background. FTY720 lowers the peripheral lymphocyte count (PLC) by accelerating the migration of circulating lymphocytes to secondary lymphoid organs. We investigated the efficacy of combined FTY720+cyclosporine (CsA) treatment versus monotherapy on
Publikováno v:
Transplantation. 69:2525-2530
Background. Graft vessel disease (GVD) is an important problem often responsible for late graft loss. The effects of FTY720, an immunomodulator with a novel mechanism of action were investigated in combination with cyclosporine A (CsA) in a carotid a
Publikováno v:
Transplant Immunology. 8:115-124
Objective: The new immunomodulator 2-amino-2-(2-{4-octylphenyl}ethyl)-1,3-propanediol hydrochloride (FTY720) lowers the peripheral lymphocyte count (PLC) by inducing migration of circulating lymphocytes to secondary lymphoid organs. This effect is do
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 355:483-490
The effect of activators of protein kinase A on membrane K+ permeability and the interaction of these compounds with cromakalim, an opener of ATP-sensitive K+ channels (K(ATP) channels), were investigated. Membrane K+ permeability was assessed by mea
Autor:
Ulrich Quast, Yves Baumlin
Publikováno v:
European Journal of Pharmacology. 200:239-249
The effects of the K+ channel opener cromakalim on phasic contractions induced by noradrenaline and caffeine were studied in the rat isolated mesenteric bed. In the presence of 1.4 mM Ca2+, 1-s pulses of noradrenaline increased the perfusion pressure
Autor:
Matthias Müller, Robert P. Hof, Akiko Hof, Margaret F. Prescott, Yuji Matsumoto, Yves Baumlin
Publikováno v:
Transplantation. 76(11)
Background. Recent observations have demonstrated the importance of host cells in neointima formation after transplantation. Because little is known regarding the dynamics of host-derived cells in the graft media, we investigated this question in a m
Publikováno v:
Transplantation. 74(10)
Background. Mycophenolate sodium (MPS), which is in clinical development as an enteric-coated tablet (Myfortic), has not yet been characterized as a combination partner of FTY720. We therefore report here the effects of MPS and FTY720 mono and combin