Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Yves A Muller"'
Autor:
Johannes Schweininger, Myriam Scherer, Franziska Rothemund, Eva-Maria Schilling, Sonja Wörz, Thomas Stamminger, Yves A Muller
Publikováno v:
PLoS Pathogens, Vol 17, Iss 8, p e1009863 (2021)
Restriction factors are potent antiviral proteins that constitute a first line of intracellular defense by blocking viral replication and spread. During co-evolution, however, viruses have developed antagonistic proteins to modulate or degrade the re
Externí odkaz:
https://doaj.org/article/77fb03220dbd48e8b450e0768989907b
Autor:
Britta Peters, Johanna Stein, Stefan Klingl, Nathalie Sander, Achim Sandmann, Nicola Taccardi, Heinrich Sticht, Roman G Gerlach, Yves A Muller, Michael Hensel
Publikováno v:
PLoS Pathogens, Vol 13, Iss 5, p e1006418 (2017)
The giant non-fimbrial adhesin SiiE of Salmonella enterica mediates the first contact to the apical site of epithelial cells and enables subsequent invasion. SiiE is a 595 kDa protein composed of 53 repetitive bacterial immunoglobulin (BIg) domains a
Externí odkaz:
https://doaj.org/article/f535a3159d0b4541a33ae26f2e629f81
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0157691 (2016)
Small molecule effectors regulate gene transcription in bacteria by altering the DNA-binding affinities of specific repressor proteins. Although the GntR proteins represent a large family of bacterial repressors, only little is known about the allost
Externí odkaz:
https://doaj.org/article/ee6324647e2f438b9ac2475546c7484c
Autor:
Myriam Scherer, Stefan Klingl, Madhumati Sevvana, Victoria Otto, Eva-Maria Schilling, Joachim D Stump, Regina Müller, Nina Reuter, Heinrich Sticht, Yves A Muller, Thomas Stamminger
Publikováno v:
PLoS Pathogens, Vol 10, Iss 11, p e1004512 (2014)
PML nuclear bodies (PML-NBs) are enigmatic structures of the cell nucleus that act as key mediators of intrinsic immunity against viral pathogens. PML itself is a member of the E3-ligase TRIM family of proteins that regulates a variety of innate immu
Externí odkaz:
https://doaj.org/article/47d27189eed2467bbda44841f214bda6
Autor:
Nadja Spindler, Uschi Diestel, Joachim D Stump, Anna-Katharina Wiegers, Thomas H Winkler, Heinrich Sticht, Michael Mach, Yves A Muller
Publikováno v:
PLoS Pathogens, Vol 10, Iss 10, p e1004377 (2014)
Human cytomegalovirus (HCMV) infections are life-threating to people with a compromised or immature immune system. Upon adhesion, fusion of the virus envelope with the host cell is initiated. In this step, the viral glycoprotein gB is considered to r
Externí odkaz:
https://doaj.org/article/7f586ff7030f4ab49d370e09ebe9f81c
Autor:
Uschi Diestel, Marcus Resch, Kathrin Meinhardt, Sigrid Weiler, Tina V Hellmann, Thomas D Mueller, Joachim Nickel, Jutta Eichler, Yves A Muller
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e67214 (2013)
The zona pellucida (ZP) domain is present in extracellular proteins such as the zona pellucida proteins and tectorins and participates in the formation of polymeric protein networks. However, the ZP domain also occurs in the cytokine signaling co-rec
Externí odkaz:
https://doaj.org/article/beba21ca4da24ded92fb277fea7ea3aa
Autor:
Manfred Lehner, Gabriel Götz, Julia Proff, Niels Schaft, Jan Dörrie, Florian Full, Armin Ensser, Yves A Muller, Adelheid Cerwenka, Hinrich Abken, Ornella Parolini, Peter F Ambros, Heinrich Kovar, Wolfgang Holter
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31210 (2012)
We explored the possibility to target Ewing's sarcoma family of tumors (ESFT) by redirecting T cells. To this aim, we considered NKG2D-ligands (NKG2D-Ls) as possible target antigens. Detailed analysis of the expression of MICA, MICB, ULBP-1, -2, and
Externí odkaz:
https://doaj.org/article/fe1b7ffa73194d2fa23042d04da80b5d
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52759 (2012)
Corticosteroid-binding globulin (CBG) transports glucocorticoids and progesterone in the blood and thereby modulates the tissue availability of these hormones. As a member of the serine protease inhibitor (SERPIN) family, CBG displays a reactive cent
Externí odkaz:
https://doaj.org/article/ba66483af08845779325641d2766273f
Autor:
Mark Kriegel, Yves A. Muller
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract By mediating interatomic interactions, water molecules play a major role in protein–protein, protein–DNA and protein–ligand interfaces, significantly affecting affinity and specificity. This notwithstanding, explicit water molecules ar
Externí odkaz:
https://doaj.org/article/403b5606d9794305a3ad887b9c87b35c
Autor:
Sewar Alkhashrom, Jintawee Kicuntod, Sigrun Häge, Johannes Schweininger, Yves A. Muller, Peter Lischka, Manfred Marschall, Jutta Eichler
Publikováno v:
Viruses, Vol 13, Iss 3, p 471 (2021)
Nuclear egress is an essential process in the replication of human cytomegalovirus (HCMV), as it enables the migration of newly formed viral capsids from the nucleus into the cytoplasm. Inhibition of the HCMV core nuclear egress complex (core NEC), c
Externí odkaz:
https://doaj.org/article/ed4e6ba6b5fc4389ab99a2045db689a7