Zobrazeno 1 - 10
of 395
pro vyhledávání: '"Yves, De Koninck"'
Autor:
Cassandra Deichsel, Irene Suárez-Pereira, Meritxell Llorca-Torralba, Adrián Martínez-Cortés, Carolina López-Martín, Yves De Koninck, Esther Berrocoso
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S551- (2023)
Externí odkaz:
https://doaj.org/article/ca919ab98bb2468397a2bd8d87220e7c
Autor:
C. Sahara Khademullah, Yves De Koninck
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-7 (2022)
Abstract Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder associated with the loss of cortical and spinal motor neurons (MNs) and muscle degeneration (Kiernan et al. in Lancet 377:942–955, 2011). In the preclinical setting, funct
Externí odkaz:
https://doaj.org/article/80d63dd6b4c3403c8c023bce4c5c285e
Autor:
Noosha Yousefpour, Samantha Locke, Haley Deamond, Chengyang Wang, Lucas Marques, Manon St-Louis, Johanne Ouellette, Arkady Khoutorsky, Yves De Koninck, Alfredo Ribeiro-da-Silva
Publikováno v:
Cell Reports, Vol 42, Iss 1, Pp 112010- (2023)
Summary: Neuropathic pain is a debilitating condition resulting from damage to the nervous system. Imbalance of spinal excitation and inhibition has been proposed to contribute to neuropathic pain. However, the structural basis of this imbalance rema
Externí odkaz:
https://doaj.org/article/274b550e51794c1489c6341b96573125
Autor:
Calvin Wong, Omer Barkai, Feng Wang, Carolina Thörn Perez, Shaya Lev, Weihua Cai, Shannon Tansley, Noosha Yousefpour, Mehdi Hooshmandi, Kevin C. Lister, Mariam Latif, A. Claudio Cuello, Masha Prager-Khoutorsky, Jeffrey S. Mogil, Philippe Séguéla, Yves De Koninck, Alfredo Ribeiro-da-Silva, Alexander M. Binshtok, Arkady Khoutorsky
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 15 (2022)
The encoding of noxious stimuli into action potential firing is largely mediated by nociceptive free nerve endings. Tissue inflammation, by changing the intrinsic properties of the nociceptive endings, leads to nociceptive hyperexcitability and thus
Externí odkaz:
https://doaj.org/article/486d93f8afa440fda061b38bd05ee999
Publikováno v:
Frontiers in Neural Circuits, Vol 16 (2022)
Externí odkaz:
https://doaj.org/article/f03973a8439b47959148b6b52af3b8f0
Autor:
Chantal Mérette, Holly Witteman, Marie-Pierre Gagnon, Annie Leblanc, Patrick Archambault, Richard Fleet, Émilie Dionne, Jean-Pierre Després, Matthew Menear, Michel Gilbert, Antoine Groulx, Marie-Christine Ouellet, Lily Lessard, Annie Vallieres, Marc-André Roy, Catherine Mercier, Caroline Cellard, Marie Baron, Patrick Blouin, George Tarabulsy, Francois Routhier, Marc Hébert, Yves De Koninck, Delphine Collin-Vézina, Nancy Côté, Marie-Hélène Gagné, Maripier Isabelle, Marie-Christine Saint-Jacques, Claudia Savard, Marie-Pier Déry, Éric Gagnon Geneviève Roch, Danielle Nadeau, Julie Tremblay, Marie-Claude Simard Geneviève Dionne, Martin Provencher, Marie-France Demers, Pierre Marquet, Simon Beaulieu-Bonneau Marie-Ève Lamontagne, Normand Boucher, Édith St-Hilaire, Marie-Hélène Morin, Annie Bérubé, Denis Lafortune, Luc Vigneault, Guy Poulin
Publikováno v:
BMJ Open, Vol 12, Iss 4 (2022)
Introduction The COVID-19 pandemic and associated restrictive measures have caused important disruptions in economies and labour markets, changed the way we work and socialise, forced schools to close and healthcare and social services to reorganise.
Externí odkaz:
https://doaj.org/article/83666b09c51e482ab2dbc2783dcc6480
Autor:
Francesco Ferrini, Jimena Perez-Sanchez, Samuel Ferland, Louis-Etienne Lorenzo, Antoine G. Godin, Isabel Plasencia-Fernandez, Martin Cottet, Annie Castonguay, Feng Wang, Chiara Salio, Nicolas Doyon, Adalberto Merighi, Yves De Koninck
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Inhibition in spinal nociceptive pathways is weaker and more labile in lamina I —where thermal input is primarily processed— than in lamina II that encodes predominantly high threshold mechanical input. This explains why noxious thermal input mak
Externí odkaz:
https://doaj.org/article/4ac2ed6526874748a22aff64150835ea
Autor:
Louis-Etienne Lorenzo, Antoine G. Godin, Francesco Ferrini, Karine Bachand, Isabel Plasencia-Fernandez, Simon Labrecque, Alexandre A. Girard, Dominic Boudreau, Irenej Kianicka, Martin Gagnon, Nicolas Doyon, Alfredo Ribeiro-da-Silva, Yves De Koninck
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-23 (2020)
Disinhibition in the dorsal horn of the spinal cord may contribute to chronic pain. Here the authors show that, despite a paradoxical increase in α2/α3 subunits of the GABAA receptor in a neuropathic pain model, inhibition eventually fails due to K
Externí odkaz:
https://doaj.org/article/7e8316d0d5b2495c8bdcf34c648c6da7
Autor:
Guillaume Bilodeau, Gabriel Gagnon-Turcotte, Léonard L. Gagnon, Iason Keramidis, Igor Timofeev, Yves De Koninck, Christian Ethier, Benoit Gosselin
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
This paper presents the design and the utilization of a wireless electro-optic platform to perform simultaneous multimodal electrophysiological recordings and optogenetic stimulation in freely moving rodents. The developed system can capture neural a
Externí odkaz:
https://doaj.org/article/770cccf77d8e48888f8c560f4fff598e
Autor:
Marco Battaglia, Cornelius B Groenewald, Fiona Campbell, Simona Scaini, Yves De Koninck, Jennifer Stinson, Patrick D Quinn
Publikováno v:
Journal of Psychopharmacology. 37:437-448
The opioid crisis’ pathways from first exposure onwards to eventual illnesses and fatalities are multiple, intertwined and difficult to dissect. Here, we offer a multidisciplinary appraisal of the relationships among mental health, chronic pain, pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4c8340cdf278f848e845aee99afabd4
https://doi.org/10.1177/02698811221144635
https://doi.org/10.1177/02698811221144635