Zobrazeno 1 - 10 of 135 pro vyhledávání: '"Yves, Blériot"'
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Akademický článek
Deciphering minimal antigenic epitopes associated with Burkholderia pseudomallei and Burkholderia mallei lipopolysaccharide O-antigens
Autor: Marielle Tamigney Kenfack, Marcelina Mazur, Teerapat Nualnoi, Teresa L. Shaffer, Abba Ngassimou, Yves Blériot, Jérôme Marrot, Roberta Marchetti, Kitisak Sintiprungrat, Narisara Chantratita, Alba Silipo, Antonio Molinaro, David P. AuCoin, Mary N. Burtnick, Paul J. Brett, Charles Gauthier
Publikováno v: Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Melioidosis and glanders are multifaceted infections caused by gram-negative bacteria. Here, the authors synthesize a series of oligosaccharides that mimic the lipopolysaccharides present on the pathogens’ surface and use them to develop novel glyc
Externí odkaz: https://doaj.org/article/0b53724e03a547438b21428813ffebbe
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4
Sugar-Derived Amidines and Congeners: Structures, Glycosidase Inhibition and Applications
Autor: Yves Blériot, Nicolas Auberger, Jérôme Désiré
Publikováno v: Current Medicinal Chemistry. 29:1271-1292
Abstract: Glycosidases, the enzymes responsible for the breakdown of glycoconjugates including di-, oligo- and polysaccharides are ubiquitous through all kingdoms of life. The extreme chemical stability of the glycosidic bond combined with the cataly
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::043ca04375623fcbc93749e8ee0e6f5e
https://doi.org/10.2174/0929867329666211222164545
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5
Contributing to the Study of Enzymatic and Chemical Glycosyl Transfer Through the Observation and Mimicry of Glycosyl Cations
Autor: Yves Blériot
Publikováno v: Synthesis. 53:904-924
This account describes our efforts dedicated to: 1) the design of glycomimetics aimed at targeting therapeutically relevant carbohydrate processing enzymes, and 2) the observation, characterization, and exploitation of glycosyl cations as a tool for
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::eef453a9586a9e58ba0d4f0ccca8ed14
https://doi.org/10.1055/s-0040-1706073
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Insight into the Ferrier Rearrangement by Combining Flash Chemistry and Superacids
Autor: Jérôme Désiré, Naresh Bhuma, Agnès Martin-Mingot, Jesús Jiménez-Barbero, Bastien Michelet, Yves Blériot, Zahra Abada, Aiichiro Nagaki, Sébastien Thibaudeau, Jérôme Marrot, Ludivine Lebedel, Ana Ardá, Masahiro Takumi, Hiroki Yamashita, Ali Abou-Hassan, Yutaka Shimizu
Publikováno v: Angewandte Chemie International Edition
Angewandte Chemie International Edition, Wiley-VCH Verlag, 2021, 60 (4), pp.2036-2041. ⟨10.1002/anie.202010175⟩
International audience; The transformation of glycals into 2,3-unsaturated glycosyl derivatives, reported by Ferrier in 1962, is supposed to involve an α,β unsaturated glycosyl cation, an elusive ionic species that has still to be observed experime
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00e3faebd507ea16cb5c14e2df33c14e
https://doi.org/10.1002/ange.202010175
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7
Iminosugar-C-glycosides work as pharmacological chaperones of NAGLU, a glycosidase involved in MPS IIIB rare disease
Autor: Jérôme Désiré, Yves Blériot, Atsushi Kato, Dominic S. Alonzi, Jesús Jiménez-Barbero, Anh Tuan Tran, Julie Charollais-Thoenig, Yongmin Zhang, Matthieu Sollogoub, Alisdair B. Boraston, Yerri Jagadeesh, Terry D. Butters, Shuki Imaeda, Stéphane Demotz, Sha Zhu, Ana Poveda
Publikováno v: Chemistry-A European Journal
Chemistry-A European Journal, Wiley-VCH Verlag, 2021, ⟨10.1002/chem.202101408⟩
International audience; Mucopolysaccharidosis type IIIB is a devastating neurological disease caused by a lack of the lysosomal enzyme, aN -acetylglucosaminidase (NAGLU), leading to a toxic accumulation of heparan sulfate. Herein we explored a pharma
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b694c5a59a20a51a00ba5d7cf1c19a23
https://hal.sorbonne-universite.fr/hal-03256952
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8
Glycosyl Oxocarbenium Ions: Structure, Conformation, Reactivity, and Interactions
Autor: Yves Blériot, Ana Ardá, Antonio Franconetti, Jesús Jiménez-Barbero, Sébastien Thibaudeau, Juan Luis Asensio
Publikováno v: Addi: Archivo Digital para la Docencia y la Investigación
Universidad del País Vasco
Addi. Archivo Digital para la Docencia y la Investigación
instname
Universidad de Cantabria (UC)
Digital.CSIC. Repositorio Institucional del CSIC
Accounts of Chemical Research
Carbohydrates (glycans, saccharides, and sugars) are essential molecules in all domains of life. Research on glycoscience spans from chemistry to biomedicine, including material science and biotechnology. Access to pure and well-defined complex glyca
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36146a5f98e4426f421103ec4d93ff73
http://hdl.handle.net/10810/51741
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9
Structural and Computational Analysis of 2‐Halogeno‐Glycosyl Cations in the Presence of a Superacid: An Expansive Platform
Autor: Yves Blériot, Agnès Mingot, Nuria Aiguabella font, Ryan Gilmour, Amélie Martin, Sébastien Thibaudeau, Ana Ardá, Jesús Jiménez-Barbero, Marialuisa Aufiero, Jérôme Désiré, Ludivine Lebedel
Publikováno v: Angewandte Chemie. 131:13896-13900
An expansive NMR-based structural analysis of elusive glycosyl cations derived from natural and non-natural monosaccharides in superacids is disclosed. For the first time, it has been possible to explore the consequence of deoxygenation and halogen s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::468af84553b0873fa32748764e247e1d
https://doi.org/10.1002/ange.201907001
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