Zobrazeno 1 - 10
of 150
pro vyhledávání: '"Yves, Barral"'
Autor:
Mariana Borsa, Niculò Barandun, Fabienne Gräbnitz, Isabel Barnstorf, Nicolas S. Baumann, Katharina Pallmer, Samira Baumann, Dominique Stark, Miroslav Balaz, Nathalie Oetiker, Franziska Wagen, Christian Wolfrum, Anna Katharina Simon, Nicole Joller, Yves Barral, Roman Spörri, Annette Oxenius
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Asymmetrical cell division helps to maintain cellular heterogeneity in the T cell compartment. Here the authors examine the differential immune responses built by naive and virtual memory T cells from young and aged individuals, and explore the effec
Externí odkaz:
https://doaj.org/article/61aae8a737c543db8b183a3356289468
Autor:
Anne C Meinema, Anna Marzelliusardottir, Mihailo Mirkovic, Théo Aspert, Sung Sik Lee, Gilles Charvin, Yves Barral
Publikováno v:
eLife, Vol 11 (2022)
The nuclear pore complex (NPC) mediates nearly all exchanges between nucleus and cytoplasm, and in many species, it changes composition as the organism ages. However, how these changes arise and whether they contribute themselves to ageing is poorly
Externí odkaz:
https://doaj.org/article/02ad8641ee164d3fa34f8230d438244a
Publikováno v:
Mathematical Methods in the Applied Sciences. 46:8855-8876
We present a framework to model and provide numerical evidence for compartmentalization in the yeast endoplasmic reticulum. Measurement data is collected and an optimal control problem is formulated as a regularized inverse problem. To our knowledge,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76490432cf157539c4d190384867c9bc
https://doi.org/10.1002/mma.9021
https://doi.org/10.1002/mma.9021
Autor:
Xiuzhen Chen, Lukas A Widmer, Marcel M Stangier, Michel O Steinmetz, Jörg Stelling, Yves Barral
Publikováno v:
eLife, Vol 8 (2019)
In eukaryotes, the organization and function of the microtubule cytoskeleton depend on the allocation of different roles to individual microtubules. For example, many asymmetrically dividing cells differentially specify microtubule behavior at old an
Externí odkaz:
https://doaj.org/article/ef8119ea66ac4b69873265c7147b4eaf
Publikováno v:
Mathematical Methods in the Applied Sciences. 46
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::012034d633b2e57dbf01ba09897078f7
https://doi.org/10.1002/mma.9369
https://doi.org/10.1002/mma.9369
Autor:
Lucía Ramos-Alonso, Petter Holland, Stéphanie Le Gras, Xu Zhao, Bernard Jost, Magnar Bjørås, Yves Barral, Jorrit M. Enserink, Pierre Chymkowitch
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 120 (4)
Mitotic entry correlates with the condensation of the chromosomes, changes in histone modifications, exclusion of transcription factors from DNA, and the broad downregulation of transcription. However, whether mitotic condensation influences transcri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc6621db50fa293b424482f3cc8b98e0
https://hdl.handle.net/20.500.11850/597053
https://hdl.handle.net/20.500.11850/597053
Autor:
Jurgita Paukštytė, Rosa María López Cabezas, Yuehan Feng, Kai Tong, Daniela Schnyder, Ellinoora Elomaa, Pavlina Gregorova, Matteo Doudin, Meeri Särkkä, Jesse Sarameri, Alice Lippi, Helena Vihinen, Juhana Juutila, Anni Nieminen, Petri Törönen, Liisa Holm, Eija Jokitalo, Anita Krisko, Juha Huiskonen, L. Peter Sarin, Ville Hietakangas, Paola Picotti, Yves Barral, Juha Saarikangas
Aging is associated with progressive phenotypic changes over time. Virtually all cellular phenotypes are produced by proteins and structural alterations in proteins can lead to age-related diseases. Nonetheless, comprehensive knowledge of proteins un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2653e6bd3af38272d04ba4b577a00a2
https://doi.org/10.1101/2023.01.23.524173
https://doi.org/10.1101/2023.01.23.524173
Autor:
Sandro M. Meier, Ana-Maria Farcas, Anil Kumar, Mahdiye Ijavi, Robert T. Bill, Jörg Stelling, Eric R. Dufresne, Michel O. Steinmetz, Yves Barral
Publikováno v:
Nature Cell Biology, 25
Microtubule plus-end tracking proteins (+TIPs) control microtubule specialization and are as such essential for cell division and morphogenesis. Here we investigated interactions and functions of the budding yeast Kar9 network consisting of the core
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9dfb0e53a6eac2f665ea44a5cad9d21
Autor:
Xiuzhen Chen, Didier Portran, Lukas A. Widmer, Marcel M. Stangier, Mateusz P. Czub, Dimitris Liakopoulos, Jörg Stelling, Michel O. Steinmetz, Yves Barral
Publikováno v:
The Journal of Cell Biology, 222 (7)
Kinesins are microtubule-dependent motor proteins, some of which moonlight as microtubule polymerases, such as the yeast protein Kip2. Here, we show that the CLIP-170 ortholog Bik1 stabilizes Kip2 at microtubule ends where the motor domain of Kip2 pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2acc31dffa7ea1774a244bca167efce6
https://hdl.handle.net/20.500.11850/610531
https://hdl.handle.net/20.500.11850/610531
We present a framework to model and provide numerical evidence for compartmentalization in the yeast endoplasmic reticulum. Measurement data is collected and an optimal control problem is formulated as a regularized inverse problem. To our knowledge,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc4511494aaaedf01c18c7ab6a5c7d4d
https://doi.org/10.22541/au.166853399.95554372/v1
https://doi.org/10.22541/au.166853399.95554372/v1