Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Yveline Rival"'
Publikováno v:
Chemical and Pharmaceutical Bulletin. 50:636-639
Obesity is a common disorder in the industrialized world. The major environmental factor associated with the rising prevalence of obesity is an increasingly sedentary lifestyle, compounded by greater levels of caloric intake. Recent studies 1—12) h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2abbaf47d0d44e806ec2d342df158a71
https://doi.org/10.1248/cpb.50.636
https://doi.org/10.1248/cpb.50.636
Publikováno v:
Synthetic Communications. 32:1715-1719
A selective Y5 receptor antagonist, the hydrochloride of 2-methyl-4-pyrrolidinyl-6-[(E)-2-(3-trifluoromethylphenyl)vinyl]pyridine, can be prepared in a 7-step synthesis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::762d17d0138560ddd7c24bf5dd7fd9ac
https://doi.org/10.1081/scc-120004266
https://doi.org/10.1081/scc-120004266
Publikováno v:
Journal of Computer-Aided Molecular Design. 15:395-410
The paper describes the construction, validation and application of a structure-based 3D QSAR model of novel acetylcholinesterase (AChE) inhibitors. Initial use was made of four X-ray structures of AChE complexed with small, non-specific inhibitors t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2921b308375ea4689d91f030530b1e97
https://doi.org/10.1023/a:1011150215288
https://doi.org/10.1023/a:1011150215288
Autor:
Yveline Rival, Camille G. Wermuth
Publikováno v:
Synthetic Communications. 30:1587-1591
The hydrochloride of the tetrazolyl bioisostere of the neurotransmitter GABA can be easily prepared by means of three simple steps: a Gabriel-type substitution on 4-bromobutyronitrile with Boc2NH, a tetrazole formation by action of azidotributyltin o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8964f839e414cca51bad5b79b4448a2
https://doi.org/10.1080/00397910008087193
https://doi.org/10.1080/00397910008087193
Publikováno v:
Synthesis. 1999:1163-1168
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46bc013cf858264152e965a9c2054675
https://doi.org/10.1055/s-1999-3528
https://doi.org/10.1055/s-1999-3528
Publikováno v:
Tetrahedron Letters. 42:2115-2117
Starting from the commercially available 3-amino-6-chloropyridazine, 3-amino-6-arylpyridazines were prepared in good yields by means of a Suzuki cross-coupling reaction avoiding the somewhat lengthy four-step classic synthesis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c36b97e748122446053a4e7818a22ce6
https://doi.org/10.1016/s0040-4039(01)00134-4
https://doi.org/10.1016/s0040-4039(01)00134-4
Publikováno v:
Synthesis. 2001:0699-0701
Starting from the commercially available 1,4-dichlorophthalazine, a series of 4-aryl-1-(4-methylpiperazin-1-yl)phthalazines was prepared with good yields and under mild conditions by means of a nucleophilic aromatic substitution and a palladium-catal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51d96058af67a107cb17bf7805e286c3
https://doi.org/10.1055/s-2001-12774
https://doi.org/10.1055/s-2001-12774
Publikováno v:
ChemInform. 23
A series of 75 imidazo[1,2-a]pyrimidine derivatives were synthesized. The "in vitro" antibacterial activity of these compounds and their corresponding alpha-bromoketones against a variety of gram (+), gram (-) bacteria and Mycobacterium species is re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a47dc3265ce67a111b2ec08816e4f00f
https://doi.org/10.1002/chin.199249182
https://doi.org/10.1002/chin.199249182
Publikováno v:
ChemInform. 30
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee246ff95f74bd3ae1ae7090edcd340f
https://doi.org/10.1002/chin.199942160
https://doi.org/10.1002/chin.199942160
Autor:
Yveline Rival, Camille G. Wermuth
Publikováno v:
ChemInform. 31
The hydrochloride of the tetrazolyl bioisostere of the neurotransmitter GABA can be easily prepared by means of three simple steps: a Gabriel-type substitution on 4-bromobutyronitrile with Boc2NH, a tetrazole formation by action of azidotributyltin o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03ab957faa9086569968c71509c0352b
https://doi.org/10.1002/chin.200033130
https://doi.org/10.1002/chin.200033130