Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Yvan Verscheure"'
Autor:
C Culié, B Vacher, Christophe Pignier, Hugues Abriel, Jean-Sébastien Rougier, B Le Grand, Yvan Verscheure, Bruno Vié
Publikováno v:
British Journal of Pharmacology. 161:79-91
BACKGROUND AND PURPOSE Myocardial ischaemia is associated with perturbations of electrophysiological profile of cardiac myocytes. The persistent sodium current (INap) is one of the major contributors to ischaemic arrhythmias and appears as an attract
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e61e4e50e4eaf69e3e164363190b00a8
https://doi.org/10.1111/j.1476-5381.2010.00884.x
https://doi.org/10.1111/j.1476-5381.2010.00884.x
Donitriptan, a Unique High-Efficacy 5-HT1B/1D Agonist: Key Features and Acute Antimigraine Potential
Autor:
Francis Colpaert, Gareth W. John, Bruno Le Grand, Yvan Verscheure, Michel Perez, Petrus J. Pauwels
Publikováno v:
CNS Drug Reviews. 6:278-289
We hypothesized that the limited acute therapeutic effectiveness of tryptamine derivatives in alleviating migraine headache could be explained by the relatively low intrinsic activity of these agents at 5-HT1B/1D receptors. Donitriptan is a novel ary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb263e25d2d1da81cf184165500b89ab
https://doi.org/10.1111/j.1527-3458.2000.tb00153.x
https://doi.org/10.1111/j.1527-3458.2000.tb00153.x
Autor:
Michel Perez, Yvan Verscheure, Robert Létienne, Francis Colpaert, Bruno Le Grand, Gareth W. John
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 305:749-754
The effects of donitriptan on systemic arterial-jugular venous oxygen saturation difference were evaluated in pentobarbitone-anesthetized pigs. Oxygen and carbon dioxide partial pressures in systemic arterial and jugular venous blood as well as hemog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90cedcbeaccce2472c115549ea68ca09
https://doi.org/10.1124/jpet.102.047225
https://doi.org/10.1124/jpet.102.047225
Autor:
Christophe Pignier, Didier Junquero, Yvan Verscheure, Stéphane N. Hatem, Alain Latil, Robert Létienne, Nathalie Mougenot, Bruno Le Grand
Publikováno v:
The FASEB Journal. 28
Atrial fibrillation (AF) can be triggered by myocardial infarction (MI) or heart failure (HF). The blockade of the ultra-rapid outward rectifier potassium current IKur is an attractive goal to control the repolarization of cardiac atria. F17727 was e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4c7ae5f94c7fde4ddbdf8296595c586
https://doi.org/10.1096/fasebj.28.1_supplement.652.17
https://doi.org/10.1096/fasebj.28.1_supplement.652.17
Publikováno v:
Journal of Cardiovascular Pharmacology. 25:126-133
We investigated the antiischemic and antiarrhythmic effects of R 56865 in pentobarbital-anesthetized, open-chest rabbits subjected to 10 min regional myocardial ischemia and 20 min reperfusion, using two experimental protocols. In the first, R 56865
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9570a138af457d517ddf85145434087c
https://doi.org/10.1097/00005344-199501000-00020
https://doi.org/10.1097/00005344-199501000-00020
Publikováno v:
British journal of pharmacology. 156(2)
BACKGROUND AND PURPOSE: Activation of the persistent sodium current in ischaemic myocardium results in calcium overload which is toxic for the cardiomyocyte. Thus, the activity of 3-(R)-[3-(2-methoxyphenylthio-2-(S)-methylpropyl]amino-3,4-dihydro-2H-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef2adf026e82027f033f31368c02121e
https://pubmed.ncbi.nlm.nih.gov/19133984
https://pubmed.ncbi.nlm.nih.gov/19133984
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 307(1)
The effects of naratriptan, rizatriptan, and sumatriptan on arteriovenous oxygen saturation difference and carotid hemodynamics were compared in the anesthetized pig. Oxygen and carbon dioxide partial pressures in systemic arterial and jugular venous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86c61dc67d9d2045b5d692469894f5b1
https://pubmed.ncbi.nlm.nih.gov/12954804
https://pubmed.ncbi.nlm.nih.gov/12954804
Publikováno v:
Pharmacological Research. 31:246
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d96408bf4baf3a792391c5e3e56f24e4
https://doi.org/10.1016/1043-6618(95)87244-2
https://doi.org/10.1016/1043-6618(95)87244-2