Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Yvan Boublik"'
Autor:
Emilie Le Goff, Camille Martinand-Mari, Marianne Martin, Jérôme Feuillard, Yvan Boublik, Nelly Godefroy, Paul Mangeat, Stephen Baghdiguian, Giacomo Cavalli
Publikováno v:
Biology Open, Vol 4, Iss 9, Pp 1109-1121 (2015)
The paradigm of developmental regulation by Polycomb group (PcG) proteins posits that they maintain silencing outside the spatial expression domains of their target genes, particularly of Hox genes, starting from mid embryogenesis. The Enhancer of ze
Externí odkaz:
https://doaj.org/article/cd243a1186a24c618477e4854e0f8c91
Autor:
Delphine Destoumieux-Garzón, Michel Brehelin, Philippe Bulet, Yvan Boublik, Pierre-Alain Girard, Stephen Baghdiguian, Robert Zumbihl, Jean-Michel Escoubas
Publikováno v:
PLoS ONE, Vol 4, Iss 8, p e6795 (2009)
BACKGROUND:X-tox proteins are a family of immune-related proteins only found in Lepidoptera and characterized by imperfectly conserved tandem repeats of several defensin-like motifs. Previous phylogenetic analysis of X-tox genes supported the hypothe
Externí odkaz:
https://doaj.org/article/7b71f8e1ea854c578ff0167616742778
Autor:
Irrem-Laareb Mohammad, Javier Carvajal, Alejandro Fernández, Marta Taulés, Elise Fourgous, Yvan Boublik, Anabel-Lise Le Roux, Serge Roche, Miquel Pons
The membrane-anchored c-Src tyrosine kinase mediates signaling from a wide range of cell surface receptors controlling cell growth, adhesion, and survival. c-Src deregulation is associated with cancer. Dimerization appears to be a novel layer of regu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::444151c48af76eafe062015b5f459f2d
https://doi.org/10.1101/2022.05.31.494233
https://doi.org/10.1101/2022.05.31.494233
Autor:
Youcef Ounoughene, Elise Fourgous, Yvan Boublik, Estelle Saland, Nathan Guiraud, Christian Recher, Serge Urbach, Philippe Fort, Jean-Emmanuel Sarry, Didier Fesquet, Serge Roche
Publikováno v:
Cancers; Volume 13; Issue 24; Pages: 6344
Cancers
Cancers, MDPI, 2021, 13 (24), pp.6344. ⟨10.3390/cancers13246344⟩
Cancers, Vol 13, Iss 6344, p 6344 (2021)
Cancers, 2021, 13 (24), pp.6344. ⟨10.3390/cancers13246344⟩
Cancers
Cancers, MDPI, 2021, 13 (24), pp.6344. ⟨10.3390/cancers13246344⟩
Cancers, Vol 13, Iss 6344, p 6344 (2021)
Cancers, 2021, 13 (24), pp.6344. ⟨10.3390/cancers13246344⟩
Simple Summary The human kinome is composed of about 50 pseudo-kinases with unclear function, because they are predicted to be catalytically inactive; however, they are shown to play an important role in cancer, similar to active kinases. Understandi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d316c19563527e597840a4384ce9653
Autor:
Serge Roche, Jean-Emmanuel Sarry, Serge Urbach, Estelle Saland, Nathan Guiraud, youcef Ounoughene, Elise fourgous, Philippe Fort, Yvan Boublik, Didier Fesquet, Christian Recher
The PEAK1 and pragmin/PEAK2 pseudo-kinases have emerged as important components of the protein tyrosine kinase pathway implicated in cancer progression. They can signal by a scaffolding mechanism that involves a conserved split helical dimerization (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eaf97ca7f173eb10f576aac4df28bed
https://doi.org/10.1101/2021.08.30.457780
https://doi.org/10.1101/2021.08.30.457780
Autor:
Céline Lecointre, Elise Fourgous, Ingrid Montarras, Clément Kerneur, Valérie Simon, Yvan Boublik, Débora Bonenfant, Bruno Robert, Pierre Martineau, Serge Roche
Publikováno v:
Cancers; Volume 14; Issue 12; Pages: 2981
The PEAK family pseudokinases are essential components of tyrosine kinase (TK) pathways that regulate cell growth and adhesion; however, their role in human cancer remains unclear. Here, we report an oncogenic activity of the pseudokinase PEAK2 in co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90ea89a1f75ce127a02877485e4fc8e9
https://doi.org/10.3390/cancers14122981
https://doi.org/10.3390/cancers14122981
Autor:
Emilie Aponte, Marie Lafitte, Audrey Sirvent, Valérie Simon, Maud Barbery, Elise Fourgous, Yvan Boublik, Mariano Maffei, Florence Armand, Romain Hamelin, Julie Pannequin, Philippe Fort, Miquel Pons, Serge Roche
Publikováno v:
Oncogene
Oncogene, 2022, 41 (7), pp.960-970. ⟨10.1038/s41388-021-02092-x⟩
Oncogene, 2022, 41 (7), pp.960-970. ⟨10.1038/s41388-021-02092-x⟩
The membrane-anchored Src tyrosine kinase is involved in numerous pathways and its deregulation is involved in human cancer. Our knowledge on Src regulation relies on crystallography, which revealed intramolecular interactions to control active Src c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f199559a6030e0e12bb43dde0ee93e9a
https://pubmed.ncbi.nlm.nih.gov/35190643
https://pubmed.ncbi.nlm.nih.gov/35190643
Autor:
Emilie Aponte, Marie Lafitte, Audrey Sirvent, Valérie Simon, Maud Barbery, Elise Fourgous, Yvan Boublik, Mariano Maffei, Florence Armand, Romain Hamelin, Julie Pannequin, Philippe Fort, Miquel Pons, Serge Roche
Publikováno v:
Oncogene. 41:2786-2786
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79e37422cb3d10bcebf9f00f9b764eef
https://doi.org/10.1038/s41388-022-02231-y
https://doi.org/10.1038/s41388-022-02231-y
Autor:
Nelly Godefroy, Camille Martinand-Mari, Paul Mangeat, Marianne Martin, Jérôme Feuillard, Emilie Le Goff, Stephen Baghdiguian, Giacomo Cavalli, Yvan Boublik
Publikováno v:
Biology Open, Vol 4, Iss 9, Pp 1109-1121 (2015)
Biology Open
Biology Open, 2015, 4 (9), pp.1109-1121. ⟨10.1242/bio.010835⟩
Biology Open, Royal Society, 2015, 4 (9), pp.1109-1121. ⟨10.1242/bio.010835⟩
Biology Open
Biology Open, 2015, 4 (9), pp.1109-1121. ⟨10.1242/bio.010835⟩
Biology Open, Royal Society, 2015, 4 (9), pp.1109-1121. ⟨10.1242/bio.010835⟩
The paradigm of developmental regulation by Polycomb group (PcG) proteins posits that they maintain silencing outside the spatial expression domains of their target genes, particularly of Hox genes, starting from mid embryogenesis. The Enhancer of ze
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61526dbbf36b729180e4f51079c713a5
http://bio.biologists.org/content/4/9/1109
http://bio.biologists.org/content/4/9/1109
Autor:
Yvan Boublik, Mehdi Chenik, Hechmi Louzir, Yosser Ben Achour-Chenik, Ahlem Aamouri, Inès Lakhal-Naouar, Abdellatif Fattoum, Mounira Meddeb
Publikováno v:
Biochemical and Biophysical Research Communications
Biochemical and Biophysical Research Communications, Elsevier, 2008, 375 (1), pp.54-8. ⟨10.1016/j.bbrc.2008.07.099⟩
Biochemical and Biophysical Research Communications, Elsevier, 2008, 375 (1), pp.54-8. ⟨10.1016/j.bbrc.2008.07.099⟩
International audience; We report the characterization of a new Leishmania major gene, lmaj3'nt/nu, encoding a 382 amino acids protein, Lmaj3'NT/NU, that belongs to the 3'nucleotidase/nuclease family. Interestingly, sequence and phylogenetic analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8e0627ed4351123d5f69a48e90eff24
https://doi.org/10.1016/j.bbrc.2008.07.099
https://doi.org/10.1016/j.bbrc.2008.07.099