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The Expression of Presenilin 1 mRNA in Skin Fibroblasts and Brains from Sporadic Alzheimer’s Disease
Autor:
Hiroyuki Arai, Kazuyuki Ikeda, Kenji Wada, Yoshiki Adachi, Kousaku Ohno, Yukihiro Ishikawa, Katsuya Urakami, Kenji Nakashima, Akitsugu Okada, Yuzuru Ohtsuka, Hidetada Sasaki, Hisanori Kowa, Y. Ji, Yosuke Wakutani
Publikováno v:
Dementia and Geriatric Cognitive Disorders. 11:245-250
We examined the expression of presenilin 1 (PS-1) mRNA in cultured skin fibroblasts taken from living patients with Alzheimer’s disease (AD) and human brains taken postmortem from AD patients by RT-PCR analysis. The donors of fibroblasts consisted