Zobrazeno 1 - 10
of 502
pro vyhledávání: '"Yuzuru Kanakura"'
Autor:
Aya Nakaya, Hirohiko Shibayama, Eiji Nakatani, Yuji Shimura, Satoru Kosugi, Hirokazu Tanaka, Shin‐Ichi Fuchida, Junya Kanda, Nobuhiko Uoshima, Hitomi Kaneko, Kazunori Imada, Kensuke Ohta, Tomoki Ito, Hideo Yagi, Satoshi Yoshihara, Masayuki Hino, Chihiro Shimazaki, Akifumi Takaori‐Kondo, Junya Kuroda, Itaru Matsumura, Yuzuru Kanakura, Shosaku Nomura
Publikováno v:
eJHaem, Vol 2, Iss 4, Pp 765-773 (2021)
Abstract A total of 129 symptomatic patients with multiple myeloma (MM) who underwent high‐dose chemotherapy with autologous stem cell transplantation (HDT/ASCT) were analyzed. The 4‐year overall survival (OS) of patients with maintenance (n = 82
Externí odkaz:
https://doaj.org/article/fca8d9086da64417a2e3ae2412495e6f
Autor:
Yoshiyuki Onda, Junya Kanda, Hitomi Kaneko, Yuji Shimura, Shin-ichi Fuchida, Aya Nakaya, Tomoki Itou, Ryosuke Yamamura, Hirokazu Tanaka, Hirohiko Shibayama, Yutaka Shimazu, Hitoji Uchiyama, Satoshi Yoshihara, Yoko Adachi, Mitsuhiro Matsuda, Hitoshi Hanamoto, Nobuhiko Uoshima, Satoru Kosugi, Kensuke Ohta, Hideo Yagi, Yuzuru Kanakura, Itaru Matsumura, Masayuki Hino, Shosaku Nomura, Chihiro Shimazaki, Akifumi Takaori-Kondo, Junya Kuroda
Publikováno v:
Therapeutic Advances in Hematology, Vol 13 (2022)
Background: Little is known about the real-world survival benefits and safety profiles of carfilzomib–lenalidomide–dexamethasone (KRd) and carfilzomib–dexamethasone (Kd). Methods: We performed a retrospective analysis to evaluate their efficacy
Externí odkaz:
https://doaj.org/article/c8a169335f1a487791719eaf9c1c6082
Autor:
Jun-ichi Nishimura, Kiyoshi Ando, Masayoshi Masuko, Hideyoshi Noji, Yoshikazu Ito, Jiri Mayer, Laimonas Griskevicius, Christoph Bucher, Florian Müllershausen, Peter Gergely, Izabela Rozenberg, Anna Schubart, Raghav Chawla, Jean-Michel Rondeau, Michael Roguska, Igor Splawski, Mark T. Keating, Leslie Johnson, Rambabu Danekula, Morten Bagger, Yoko Watanabe, Börje Haraldsson, Yuzuru Kanakura
Publikováno v:
Haematologica, Vol 107, Iss 6 (2022)
Externí odkaz:
https://doaj.org/article/c663a2a787414f439fa282c457416a6b
Autor:
Kenji Nozaki, Takafumi Yokota, Eri Itotagawa, Kazuhito Tsutsumi, Shinsuke Kusakabe, Yoichiro Morikawa, Jiro Fujita, Kentaro Fukushima, Tetsuo Maeda, Hirohiko Shibayama, Naoki Hosen, Atsushi Kumanogo, Yuzuru Kanakura
Publikováno v:
Clinical Case Reports, Vol 8, Iss 11, Pp 2251-2254 (2020)
Abstract We believe that our report and further case reports on T‐cell chronic lymphocytic leukemia with genetic profile will contribute to the molecular classification of this rare but distinct disease.
Externí odkaz:
https://doaj.org/article/678bcedaa85843b4bef2e145f2e30e25
Autor:
Shinya Rai, Hirokazu Tanaka, Mai Suzuki, J. Luis Espinoza, Takahiro Kumode, Akira Tanimura, Takafumi Yokota, Kenji Oritani, Toshio Watanabe, Yuzuru Kanakura, Itaru Matsumura
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Receptor tyrosine kinase mutations are frequent and associated with poor prognosis in acute myeloid leukemia (AML). Here the authors show that the antipsychotic drug chlorpromazine reduces AML cells viability by perturbing the intracellular localizat
Externí odkaz:
https://doaj.org/article/8d959de3d6524e5897ad361f125459c1
Autor:
Tomoaki Ueda, Takafumi Yokota, Daisuke Okuzaki, Yoshihiro Uno, Tomoji Mashimo, Yoshiaki Kubota, Takao Sudo, Tomohiko Ishibashi, Yasuhiro Shingai, Yukiko Doi, Takayuki Ozawa, Ritsuko Nakai, Akira Tanimura, Michiko Ichii, Sachiko Ezoe, Hirohiko Shibayama, Kenji Oritani, Yuzuru Kanakura
Publikováno v:
Stem Cell Reports, Vol 13, Iss 6, Pp 992-1005 (2019)
Summary: Endothelial cell-selective adhesion molecule (ESAM) is a lifelong marker of hematopoietic stem cells (HSCs). Although we previously elucidated the functional importance of ESAM in HSCs in stress-induced hematopoiesis in adults, it is unclear
Externí odkaz:
https://doaj.org/article/2f1cc39118884a53a41bfddd7f92b5a0
Autor:
Michiko Ichii, Kenji Oritani, Jun Toda, Hideaki Saito, Henyun Shi, Hirohiko Shibayama, Daisuke Motooka, Yuichi Kitai, Ryuta Muromoto, Jun-ichi Kashiwakura, Kodai Saitoh, Daisuke Okuzaki, Tadashi Matsuda, Yuzuru Kanakura
Publikováno v:
Haematologica, Vol 106, Iss 2 (2020)
Signal-transducing adaptor protein-2 (STAP-2) was discovered as a C-FMS/M-CSFR interacting protein and subsequently found to function as an adaptor of signaling or transcription factors. These include STAT5, MyD88 and IκB kinase in macrophages, mast
Externí odkaz:
https://doaj.org/article/138b5f117e5347b9aa4e85806685e47d
Autor:
Yukiko Doi, Takafumi Yokota, Yusuke Satoh, Daisuke Okuzaki, Masahiro Tokunaga, Tomohiko Ishibashi, Takao Sudo, Tomoaki Ueda, Yasuhiro Shingai, Michiko Ichii, Akira Tanimura, Sachiko Ezoe, Hirohiko Shibayama, Terumi Kohwi-Shigematsu, Junji Takeda, Kenji Oritani, Yuzuru Kanakura
Publikováno v:
Cell Reports, Vol 23, Iss 11, Pp 3223-3235 (2018)
Summary: Hematopoietic stem cells (HSCs) comprise a heterogeneous population exhibiting self-renewal and differentiation capabilities; however, the mechanisms involved in maintaining this heterogeneity remain unclear. Here, we show that SATB1 is invo
Externí odkaz:
https://doaj.org/article/ee6c510eeb5b4d29ad6a2a3651c1dd7a
Autor:
Takahiro Matsui, Tetsuo Maeda, Shinsuke Kusakabe, Hideyuki Arita, Kenji Yagita, Eiichi Morii, Yuzuru Kanakura
Publikováno v:
Diagnostic Pathology, Vol 13, Iss 1, Pp 1-6 (2018)
Abstract Background The diagnosis of granulomatous amoebic encephalitis is challenging for clinicians because it is a rare and lethal disease. Previous reports have indicated that Acanthamoeba with some specific genotypes tend to cause the majority o
Externí odkaz:
https://doaj.org/article/9a4728c3cf34442dafcfd01f2f5a79e9
Autor:
Aya Nakaya, Hideo Yagi, Hitomi Kaneko, Satoru Kosugi, Toru Kida, Yoko Adachi, Hirohiko Shibayama, Takae Kohara, Yuri Kamitsuji, Shin-ichi Fuchida, Nobuhiko Uoshima, Eri Kawata, Hitoji Uchiyama, Yuji Shimura, Takayuki Takahashi, Fumiaki Urase, Kensuke Ohta, Tsuneyoshi Hamada, Kazue Miyamoto, Masayuki Kobayashi, Maki Shindo, Hirokazu Tanaka, Chihiro Shimazaki, Masayuki Hino, Junya Kuroda, Yuzuru Kanakura, Akifumi Takaoari-Kondo, Shosaku Nomura, Itaru Matsumura
Publikováno v:
Leukemia Research Reports, Vol 10, Iss , Pp 7-10 (2018)
We retrospectively analyzed twenty-six patients with primary plasma cell leukemia (pPCL) registered from May 2005 until April 2015 by the Kansai Myeloma Forum. Twenty patients received novel agents (bortezomib or lenalidomide), and their median survi
Externí odkaz:
https://doaj.org/article/60725e003e734cd185128c760bbe013a