Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Yuzuru Akamatsu"'
Autor:
Hideki Hashizume, Chisato Nosaka, Sehei Hirosawa, Masayuki Igarashi, Yoshio Nishimura, Yuzuru Akamatsu
Publikováno v:
ARKIVOC, Vol 2007, Iss 7, Pp 241-253 (2006)
Externí odkaz:
https://doaj.org/article/65dd030009f9454da435e5c14c3fd0f9
Autor:
Kazushige Sasaki, Yuzuru Akamatsu, Yohei Yamashita, Yoshihiko Kobayashi, Yoshiaki Takahashi, Takashi Kurihara, Toshiaki Miyake
Publikováno v:
The Journal of Antibiotics. 68:741-747
Arbekacin, an aminoglycoside antibiotic, is an important drug because it shows a potent efficacy against methicillin-resistant Staphylococcus aureus. However, resistance to arbekacin, which is caused mainly by the bifunctional aminoglycoside-modifyin
Autor:
Yuzuru Akamatsu, Toshiaki Miyake, Atsushi Seki, Kouji Sasaki, Yoshiaki Takahashi, Toshihiro Mori
Publikováno v:
MedChemComm. 6:581-585
The synthesis of 17-membered azalides was achieved using the following key steps: (i) Beckmann rearrangement of 16-membered oxime derivatives obtained from 3,4′-dideoxymycaminosyltylonolide (DDMT), (ii) amide-selective silane reduction of the corre
Autor:
Masayuki Igarashi, Hideki Hashizume, Yoshio Nishimura, Yuzuru Akamatsu, Ryuichi Sawa, Hayamitsu Adachi
Publikováno v:
The Journal of antibiotics. 69(12)
Correction to: The Journal of Antibiotics (2008) 61, 577–582; doi:10.1038/ja.2008.78 The authors of the above article misjudged the stereochemistry of constituent serine residue that was determined by Marfey’s method using HPLC, which was the sam
Autor:
Masayuki Igarashi, Seiko Hattori, Yoshiaki Takahashi, Norio Doi, Yuzuru Akamatsu, Naoko Nakagawa, Yoshiko Koyama, Toshiaki Miyake, Kanae Ishikawa, Kunio Inoue, Yasuhiro Komatsuki, Hiromi Soutome
Publikováno v:
The Journal of Antibiotics. 66:171-178
Acidic treatment of a mixture of caprazamycins (CPZs) A-G isolated from a screen of novel antimycobacterial agents gave caprazene, a core structure of CPZs, in high yield. Chemical modification of the resulting caprazene was performed to give its var
Autor:
Yuzuru Akamatsu
Publikováno v:
Proceedings of the Japan Academy. Series B, Physical and Biological Sciences
By using "our devised up-to-the-second technique" over 30 years ago, we succeeded in the first isolation in the world of the three different kinds of mammalian cell mutants defective in the biosynthesis on each of phosphatidylserine (PS), cardiolipin
Autor:
Takumi Watanabe, Yoshikazu Takahashi, Daishiro Ikeda, Isao Momose, Hikaru Abe, Yuzuru Akamatsu
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 20:5839-5842
The structure-activity relationship of the boronic acid derivatives of tyropeptin, a proteasome inhibitor, was studied. Based on the structure of a previously reported boronate analog of tyropeptin (2), 41 derivatives, which have varying substructure
Autor:
Ryuichi Sawa, Naoko Kinoshita, Yoshio Nishimura, Fukiko Kojima, Koichi Nakae, Yuzuru Akamatsu, Masayuki Igarashi, Hayamitu Adachi, Yumiko Kubota
Publikováno v:
The Journal of Antibiotics. 63:41-44
Antipain Y, a new antipain analog that inhibits neurotransmitter release from rat dorsal root ganglion neurons
Autor:
Masayuki Igarashi, Hayamitsu Adachi, Yoshio Nishimura, Ryuichi Sawa, Yuzuru Akamatsu, Hideki Hashizume
Publikováno v:
The Journal of Antibiotics. 61:577-582
Branched chain amino acids are often utilized as the precursors of many lipid-containing bacterial secondary metabolites. The effect of isoleucine on the composition of the mixture of cyclic lipopeptide antibiotics, tripropeptins from Lysobacter sp.
Autor:
Hotta Kunimoto, Yuzuru Akamatsu, Ken-ichiro Kondo, Yoshio Nishimura, Fukiko Kojima, Hayamitsu Adachi, Yoji Umezawa, Keiko Ishino
Publikováno v:
Letters in Drug Design & Discovery. 5:336-339