Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Yuzu Anazawa"'
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(32)
KIF1A is a kinesin superfamily motor protein that transports synaptic vesicle precursors in axons. Cargo binding stimulates the dimerization of KIF1A molecules to induce processive movement along microtubules. Mutations in human Kif1a lead to a group
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7de37a068b61747aa5bfed6ff2216fc7
https://pubmed.ncbi.nlm.nih.gov/35917346
https://pubmed.ncbi.nlm.nih.gov/35917346
Publikováno v:
Journal of Cell Science. 136
Neuronal function depends on axonal transport by kinesin superfamily proteins (KIFs). KIF1A is the molecular motor that transports synaptic vesicle precursors, synaptic vesicles, dense core vesicles and active zone precursors. KIF1A is regulated by a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8cbbbec2a62e934844a26d91f65174b8
https://doi.org/10.1242/jcs.260742
https://doi.org/10.1242/jcs.260742
Autor:
Yuzu, Anazawa, Shinsuke, Niwa
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2431
The development and functions of neurons are supported by axonal transport. Axonal transport is a complex process whose regulation involves multiple molecules, such as microtubules, microtubule-associated proteins, kinases, molecular motors, and moto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7343c8a75024965eadcc7d18329197f7
https://pubmed.ncbi.nlm.nih.gov/35412293
https://pubmed.ncbi.nlm.nih.gov/35412293
Autor:
Yuzu Anazawa, Shinsuke Niwa
Publikováno v:
Methods in Molecular Biology ISBN: 9781071619896
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ed0c52e3e503260a757a7197d3584d7
https://doi.org/10.1007/978-1-0716-1990-2_25
https://doi.org/10.1007/978-1-0716-1990-2_25
KIF1A is a kinesin superfamily molecular motor that transports synaptic vesicle precursors in axons. Mutations in Kif1a lead to a group of neuronal diseases called KIF1A-associated neuronal disorder (KAND). KIF1A forms a homodimer and KAND mutations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cbfd7bb9ad8d25b8c99ce0b5003b1567
https://doi.org/10.1101/2021.07.22.453457
https://doi.org/10.1101/2021.07.22.453457
Autor:
Aileen Lam, Shinsuke Niwa, Richard J. McKenney, Kyoko Chiba, Lu Rao, Kyoko Okada, Arne Gennerich, Yuzu Anazawa, Dan W. Nowakowski, Mariah Dacy
Publikováno v:
Science Advances. 7
KIF1A is a critical cargo transport motor within neurons. More than 100 known mutations result in KIF1A-associated neurological disorder (KAND), a degenerative condition for which there is no cure. A missense mutation, P305L, was identified in childr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d5313cb9810828572df9287558f38f6
https://doi.org/10.1126/sciadv.abf1002
https://doi.org/10.1126/sciadv.abf1002
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 8/9/2022, Vol. 119 Issue 32, p1-19, 30p
Autor:
Aileen J, Lam, Lu, Rao, Yuzu, Anazawa, Kyoko, Okada, Kyoko, Chiba, Mariah, Dacy, Shinsuke, Niwa, Arne, Gennerich, Dan W, Nowakowski, Richard J, McKenney
Publikováno v:
Science Advances
An uncharacterized structural element in the kinesin motor domain is shown to be critical for motor function and human health.
KIF1A is a critical cargo transport motor within neurons. More than 100 known mutations result in KIF1A-associated neu
KIF1A is a critical cargo transport motor within neurons. More than 100 known mutations result in KIF1A-associated neu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::826a361ef44e63cfa115891a96060b53
https://pubmed.ncbi.nlm.nih.gov/33931448
https://pubmed.ncbi.nlm.nih.gov/33931448
Autor:
Dan W. Nowakowski, Arne Gennerich, Kyoko Okada, Yuzu Anazawa, Aileen Lam, Shinsuke Niwa, Richard J. McKenney, Kyoko Chiba, Lu Rao
KIF1A, a kinesin-3 family member, plays critical roles as a long-distance cargo-transporter within neurons. Over 100 known KIF1A mutations in humans result in KIF1A Associated Neurological Disease (KAND), developmental and degenerative neurological c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ffccd4d33f6320979fb361252ae8912d
https://doi.org/10.1101/2020.09.22.308320
https://doi.org/10.1101/2020.09.22.308320
Autor:
Lam, Aileen J.1, Rao, Lu2, Yuzu Anazawa3,4, Kyoko Okada1, Kyoko Chiba1,4, Dacy, Mariah1, Shinsuke Niwa4, Gennerich, Arne2 arne.gennerich@einsteinmed.org, Nowakowski, Dan W.5 publications@nmolecularsystems.com, McKenney, Richard J.1 rjmckenney@ucdavis.edu
Publikováno v:
Science Advances. 4/28/2021, Vol. 7 Issue 18, p1-14. 14p.