Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Yuzo Matsuoka"'
Publikováno v:
In Japanese Journal of Pharmacology 1999 79(3):313-317
Autor:
Yukitsuka Kudo, Hitoshi Endou, Hiroshi Iwata, Tsutomu Kobayashi, Yoshikatsu Kanai, Atsushi Nishida, Yuzo Matsuoka
Publikováno v:
Biological and Pharmaceutical Bulletin. 27:817-820
To elucidate the mechanisms of neuroprotective action of nicergoline, we examined its effect on glutamate transport in rat cortical synaptosomes and cloned glutamate transporters. In synaptosomes, nicergoline enhanced the glutamate uptake at 1-10 mic
Publikováno v:
Japanese Journal of Pharmacology. 83:119-124
Publikováno v:
CNS Drug Reviews. 4:25-41
Publikováno v:
European Journal of Pharmacology. 343:129-133
The effects of thyrotropin-releasing hormone (TRH) receptor agonists were examined on 3-acetylpyridine-induced cerebellar ataxia in rats. 3-acetylpyridine markedly decreased the maximal height of vertical jump, accompanied by motor incoordination. Bo
Autor:
Yumiko Kawashima, Michio Yamamura, Kiyoshi Kinoshita, Yuzo Matsuoka, Kazutaka Kawashima, Isao Fukuchi
Publikováno v:
Japanese Journal of Pharmacology. 71:139-145
To examine the action of a novel thyrotropin-releasing hormone (TRH) analog, TA-0910 ((—)-N-[(S)-hexahydro-1-methyl-2,6-dioxo-4-pyrimidinylcarbonyl]- L -histidyl- L -prolinamide tetrahydrate), on the cerebral cholinergic systems, the release of ace
Autor:
Michio Yamamura, Matsuko Moriyasu, Yuzo Matsuoka, Tamami Sakamoto, Hideo Honda, Masahiro Nasu
Publikováno v:
Folia Pharmacologica Japonica. 107:285-297
The stimulatory effect of TA-0910 on the secretions of thyroid-stimulating hormone (TSH) and thyroid hormones was investigated in male and female rats. Single intravenous administration of TA-0910 at 8.3 nmol/body acutely elevated the plasma TSH leve
Publikováno v:
European Journal of Pharmacology. 274:65-72
The effects of TA-0910 (1-methyl-(S)-4,5-dihydroorotyl- l -histidyl- l -prolinamide), a new thyrotropin-releasing hormone (TRH: l -pyroglutamyl- l -histidyl- l -prolinamide) analog, on ataxia were compared with those of TRH given by oral administrati
Autor:
Mamoru Suzuki, Mamoru Matsumoto, Masafumi Yamagishi, Masaaki Asao, Ryo Shimizu, Yuzo Matsuoka, Yoshihisa Yamada, Kenichi Ozaki, Kazuo Matsumoto
Publikováno v:
Journal of Medicinal Chemistry. 35:2085-2094
A series of spiro[imidazolidine-4,4'(1'H)-quinazoline]- 2,2'5(3'H)-triones were prepared and tested for aldose reductase inhibitory activity. The 6'-halogenated derivatives were found to be highly potent in vitro inhibitors of male rabbit lens aldose
Autor:
Yukitsuka Kudo, Yuzo Matsuoka, Tsutomu Kobayashi, Atsushi Nishida, Hiroshi Iwata, Yoshikatsu Kanai, Hitoshi Endou
Publikováno v:
Biologicalpharmaceutical bulletin. 27(6)
To establish an assay system for evaluation of the uptake and reversed transport of glutamate, we examined the effects of Na(+)-concentration and pharmacological agents on the extracellular glutamate concentration ([Glu](o)) in rat cortical synaptoso