Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Yuzhuo Chu"'
Publikováno v:
Molecules, Vol 20, Iss 6, Pp 10032-10046 (2015)
Protein arginine methyltransferases (PRMTs) catalyze the transfer of the methyl group from S-adenosyl-l-methionine (AdoMet) to arginine residues. There are three types of PRMTs (I, II and III) that produce different methylation products, including as
Externí odkaz:
https://doaj.org/article/79c1d62fd886443e92e372977cf93f30
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e37674 (2012)
Certain lysine residues on histone tails could be methylated by protein lysine methyltransferases (PKMTs) using S-adenosyl-L-methionine (AdoMet) as the methyl donor. Since the methylation states of the target lysines play a fundamental role in the re
Externí odkaz:
https://doaj.org/article/4fc494fa9d7544d0a44e092d30f5b64a
Autor:
Susan Krueger, Yuzhuo Chu, Cynthia B. Peterson, Vladimir N. Uversky, Christopher B. Stanley, Joseph E. Curtis, Letitia O Puster
Publikováno v:
Biochemistry
Small-angle neutron scattering (SANS) measurements were pursued to study human vitronectin, a protein found in tissues and the circulation that regulates cell adhesion/migration and proteolytic cascades that govern hemostasis and pericellular proteol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68437bd301401987b0451b3c505deeb4
https://doi.org/10.1021/acs.biochem.9b00605
https://doi.org/10.1021/acs.biochem.9b00605
Publikováno v:
Protein Sci
The serine protease inhibitor, plasminogen activator inhibitor Type‐1 (PAI‐1) is a metastable protein that undergoes an unusual transition to an inactive conformation with a short half‐life of only 1–2 hr. Circulating PAI‐1 is bound to a co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7280981b72529c03f1cc8a6e43ac758a
https://doi.org/10.1002/pro.3770
https://doi.org/10.1002/pro.3770
Publikováno v:
Protein Sci
Plasminogen activator inhibitor-1 (PAI-1) is the primary inhibitor for plasminogen activators, tissue-type plasminogen activator (tPA) and urokinase-type plasminogen activator (uPA). As a unique member in the serine protease inhibitor (serpin) family
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5aec0bf73131e9da99d52ec8a0ba28b0
https://pubmed.ncbi.nlm.nih.gov/33345392
https://pubmed.ncbi.nlm.nih.gov/33345392
Autor:
Cynthia B. Peterson, Yuzhuo Chu, Gregory L. Ware, Carlee S. McClintock, Joseph P. Emerson, Kayla D. McConnell, Joel C. Bucci
Publikováno v:
Journal of Biological Inorganic Chemistry
Components of the fibrinolytic system are subjected to stringent control to maintain proper hemostasis. Central to this regulation is the serpin plasminogen activator inhibitor-1 (PAI-1), which is responsible for specific and rapid inhibition of fibr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eee8bb773c7a0f89278d23551fbd29a2
https://doi.org/10.1007/s00775-017-1489-5
https://doi.org/10.1007/s00775-017-1489-5
Autor:
Hong Guo, Yuzhuo Chu
Publikováno v:
Interdisciplinary Sciences: Computational Life Sciences. 7:309-318
Methyl transfer processes catalyzed by protein lysine methyltransferases (PKMTs) and protein arginine methyltransferases (PRMTs) control important biological events including transcriptional regulation and cell signaling. One important property of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::715eb96b6cd5474bbfea5fe0ee9c63b8
https://doi.org/10.1007/s12539-015-0280-y
https://doi.org/10.1007/s12539-015-0280-y
Publikováno v:
Canadian Journal of Chemistry. 91:605-612
Protein arginine N-methyltransferases (PRMTs) catalyze the transfer of methyl group(s) from S-adenosyl-l-methionine (AdoMet) to the guanidine group of arginine residue in abundant eukaryotic proteins. Two major types of PRMTs have been identified in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c27b2c3d7c0d070a93cd509e2195d31c
https://doi.org/10.1139/cjc-2012-0483
https://doi.org/10.1139/cjc-2012-0483
Publikováno v:
Journal of Chemical Information and Modeling. 52:449-456
The results of hybrid quantum mechanical/molecular mechanical (QM/MM) free energy (potential of mean force) simulations for methyl-transfer processes in SET7/9 and its Y245A mutant are compared to address the question concerning the change of the pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48811ad29afbdefecd5421b5bf3454ac
https://doi.org/10.1021/ci200364m
https://doi.org/10.1021/ci200364m
Publikováno v:
Chemico-Biological Interactions. 193:50-56
A descriptor based computational model was developed for cytochrome P450 2E1 (CYP2E1) based on inhibition constants determined for inhibition of chlorzoxazone, or 4-nitrophenol, metabolism. An empirical descriptor for type II binding was developed an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15545ae4c53c64c2912a250d031f5c61
https://doi.org/10.1016/j.cbi.2011.05.001
https://doi.org/10.1016/j.cbi.2011.05.001