Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Yuzhou, Gui"'
Autor:
Hongjie Qian, Jie Cheng, Yuzhou Gui, Wei Wang, Liyu Liang, Huijuan Zhu, Qingqing Wu, Meixian Ou, Qian Chen, Chen Yu, Jingying Jia
Publikováno v:
Clinical and Translational Science, Vol 16, Iss 9, Pp 1704-1712 (2023)
Abstract This study aimed to evaluate the pharmacokinetic (PK) similarity of the proposed biosimilar HS628 compared with the reference tocilizumab (Actemra®) and also to demonstrate similar safety and immunogenicity profiles in healthy Chinese male
Externí odkaz:
https://doaj.org/article/3a81076c66c0476f8ed34e304c4e3c9d
Autor:
Yun Liu, Wei Wang, Hongjie Qian, Yuzhou Gui, Yating Wang, Rong Song, Qian Chen, Eric Rowinsky, Sheng Wang, Xiaoguang Liang, Kaicun Gu, Bo Zhou, Weiwei Zhang, Liqin Zhang, Chen Yu, Jingying Jia
Publikováno v:
Clinical and Translational Science, Vol 17, Iss 3, Pp n/a-n/a (2024)
Abstract This study evaluated the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), and food effects (FE) of SC0062, a highly active endothelin‐A (ETA) receptor antagonist, in healthy subjects. The primary objectives of this first
Externí odkaz:
https://doaj.org/article/f1f117802baf44e7857f348d41657239
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Foam cells play a vital role in the initiation and development of atherosclerosis. This review aims to summarize the novel insights into the origins, consequences, and molecular mechanisms of foam cells in atherosclerotic plaques. Foam cells are orig
Externí odkaz:
https://doaj.org/article/953aed7192a247bc8488d585887d7479
Autor:
Yuzhou Gui, Youli Lu, Shuijun Li, Mengqi Zhang, Xiaokun Duan, Charles C. Liu, Jingying Jia, Gangyi Liu
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Abstract Therapeutic drug monitoring (TDM) is necessary for the optimal administration of anti-arrhythmic drugs in the treatment of heart arrhythmia. The present study aimed to develop and validate a direct analysis in real time tandem mass spectrome
Externí odkaz:
https://doaj.org/article/385224b5c9f14bb1bbfb7fe826e73ea5
Autor:
Yuzhou Gui, Ye Cao, Jiajin He, Chunyang Zhao, Wei Zheng, Ling Qian, Jie Cheng, Chengyin Yu, Chen Yu, Kun Lou, Gangyi Liu, Jingying Jia
Publikováno v:
Life Metabolism. 2
The continuous emergence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants led to a rapid decline in protection efficacy and neutralizing titers even after three doses of COVID-19 vaccines. Here, we report an open-labeled P
Autor:
Gangyi Liu, Chunxia Dong, Weiwei Shen, Xiaopei Lu, Mengqi Zhang, Yuzhou Gui, Qinyi Zhou, Chen Yu
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 6, Iss 1, Pp 55-63 (2016)
A quantitative method for clopidogrel using online-SPE tandem LC–MS/MS was developed and fully validated according to the well-established FDA guidelines. The method achieves adequate sensitivity for pharmacokinetic studies, with lower limit of qua
Externí odkaz:
https://doaj.org/article/f3255afaf62047539bb3c67c9cd44b67
Publikováno v:
Frontiers in cardiovascular medicine. 9
Foam cells play a vital role in the initiation and development of atherosclerosis. This review aims to summarize the novel insights into the origins, consequences, and molecular mechanisms of foam cells in atherosclerotic plaques. Foam cells are orig
Autor:
Yuzhou, Gui, Chengyin, Yu, Jiaye, Zhou, Liang, Xin, Ze, Chen, Tiejiong, Fan, Shuang, Lu, Jingying, Jia, Gangyi, Liu
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 212
Daboia russelii siamensis accounts for most of snakebite mortalities in China, yet, specific treatment against the venom toxins is absent in clinical practice. The F(ab')
Autor:
Yuzhou Gui, Chengyin Yu, Jiaye Zhou, Liang Xin, Ze Chen, Tiejiong Fan, Shuang Lu, Jingying Jia, Gangyi Liu
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 212:114645
Autor:
Yuzhou Gui, Meng-qi Zhang, Jingying Jia, Gangyi Liu, Jingshan Shen, Hongjie Qian, Jiajin He, Haiming Liu, Chen Yu, Zhen Wang
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 191
A simple, rapid and accurate method for quantitative analysis of a highly selective phosphodiesterase-5 inhibitor (PDE5), TPN171 by high performance liquid chromatography and tandem mass spectrometry in human plasma was proposed and validated success