Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Yuzhen Qian"'
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract Background Colorectal cancer (CRC) is the third most prevalent cancer globally, and liver metastasis (CRLM) is the primary cause of death. Hence, it is essential to discover novel prognostic biomarkers and therapeutic drugs for CRLM. Methods
Externí odkaz:
https://doaj.org/article/65b1f28c4cbc4f1c9a0c5c5905e4656b
Autor:
Yuzhen Qian, Yixuan Sun, Peishang Shi, Xiuman Zhou, Qiongqiong Zhang, Qingyu Dong, Shengzhe Jin, Lu Qiu, Xiaoshuang Niu, Xiaowen Zhou, Wenshan Zhao, Yahong Wu, Wenjie Zhai, Yanfeng Gao
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 3, Pp 1150-1165 (2024)
Aside from antibodies, peptides show great potential as immune checkpoint inhibitors (ICIs) due to several advantages, such as better tumor penetration and lower cost. Lymphocyte-activation gene 3 (LAG-3) is an immune checkpoint which can induce T ce
Externí odkaz:
https://doaj.org/article/2ac2caa014eb4e9e8e214552da52bbd8
Autor:
Yixuan Sun, Yuzhen Qian, Chunxia Chen, Hongfei Wang, Xiuman Zhou, Wenjie Zhai, Lu Qiu, Xiaowen Zhou, Haoming Ning, Yumiao Zhao, Chao Shi, Lu Han, Yuanming Qi, Yahong Wu, Yanfeng Gao
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-22 (2022)
Abstract Background Metastasis is the leading cause of mortality in human cancers, including esophageal squamous cell carcinoma (ESCC). As a pro-inflammatory cytokine, IL-32 was reported to be a poor prognostic factor in many cancers. However, the ro
Externí odkaz:
https://doaj.org/article/46a3f121cd2b45838c425ad29e3bf0dd
Autor:
Xiuman Zhou, Ling Jiao, Yuzhen Qian, Qingyu Dong, Yixuan Sun, Wei V. Zheng, Wenshan Zhao, Wenjie Zhai, Lu Qiu, Yahong Wu, Hongfei Wang, Yanfeng Gao, Junhui Chen
Publikováno v:
Biomolecules, Vol 11, Iss 5, p 706 (2021)
Strategies boosting both innate and adaptive immunity have great application prospects in cancer immunotherapy. Antibodies dual blocking the innate checkpoint CD47 and adaptive checkpoint PD-L1 or TIGIT could achieve durable anti-tumor effects. Howev
Externí odkaz:
https://doaj.org/article/555e5a7e4aae446286a6241f38cec395
Publikováno v:
Journal of Colloid and Interface Science. 638:439-448
Publikováno v:
ACS Applied Polymer Materials. 5:2983-2994
Publikováno v:
Chemistry – A European Journal. 29
Publikováno v:
Chemistry – A European Journal. 29
Autor:
Yixuan Sun, Yuzhen Qian, Chunxia Chen, Hongfei Wang, Xiuman Zhou, Wenjie Zhai, Lu Qiu, Xiaowen Zhou, Haoming Ning, Yumiao Zhao, Chao Shi, Lu Han, Yuanming Qi, Yahong Wu, Yanfeng Gao
Publikováno v:
Journal of experimentalclinical cancer research : CR. 41(1)
Background Metastasis is the leading cause of mortality in human cancers, including esophageal squamous cell carcinoma (ESCC). As a pro-inflammatory cytokine, IL-32 was reported to be a poor prognostic factor in many cancers. However, the role of IL-
Autor:
Man, Zhang, Yining, Zhang, Xiaohong, Peng, Anshun, He, Yue, Wang, Ying, Deng, Cheng, Cui, Fangkai, Xue, Bing, Wei, Wancai, Xing, Yuzhen, Qian, Michelle, Mazuranic, Wei, Chen
Publikováno v:
European Journal of Pharmacology. 928:175107
GZR18 is a novel analog of glucagon-like peptide-1 (GLP-1). This study evaluates the pharmacology, pharmacokinetics, and efficacy of GZR18, and its potential for the treatment of Type 2 diabetes mellitus (T2DM). In vitro pharmacology and activity of