Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Yuzhe Yuan"'
Publikováno v:
Engineering Reports, Vol 6, Iss 1, Pp n/a-n/a (2024)
Abstract The recombinant adeno‐associated viral (rAAV) vector is one of the most effective viral vectors in gene therapy because of its low immunogenicity, high transduction efficiency, broad tissue specificity, and long‐term transgene expression
Externí odkaz:
https://doaj.org/article/db1b1ec849d8404b9db6069dd55e036b
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)
Abstract Several xenogenic cell-based therapeutic products are currently under development around the world for the treatment of human diseases. Porcine islet cell products for treating human diabetes are a typical example. Since porcine cells posses
Externí odkaz:
https://doaj.org/article/b4ce8d8a941048a3b91f1d31adb3cd5c
Autor:
Yuzhe Yuan, Masaru Yokoyama, Yosuke Maeda, Hiromi Terasawa, Shinji Harada, Hironori Sato, Keisuke Yusa
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65115 (2013)
Maraviroc, an (HIV-1) entry inhibitor, binds to CCR5 and efficiently prevents R5 human immunodeficiency virus type 1 (HIV-1) from using CCR5 as a coreceptor for entry into CD4(+) cells. However, HIV-1 can elude maraviroc by using the drug-bound form
Externí odkaz:
https://doaj.org/article/602ef43c6b39478c9676f5b0a53592dc
Akademický článek
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Autor:
Kiyoko Higashiyama, Yuzhe Yuan, Noriko Hashiba, Kyoko Masumi-Koizumi, Keisuke Yusa, Kazuhisa Uchida
Publikováno v:
Human Gene Therapy. 34(11-12):578-585
Recombinant adeno-associated virus (rAAV) is a viral vector commonly used in gene therapy. Residual host cell DNA is an impurity that has been associated with the risk of infection and oncogenicity. Thus, it needs to be monitored for quality control.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75119ee4adf3c03b30042396915e1f75
https://hdl.handle.net/20.500.14094/0100482541
https://hdl.handle.net/20.500.14094/0100482541
Publikováno v:
Food Chemistry. 424:136457
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::974b5d1e15ca3d9c861ac54234fbd5ea
https://doi.org/10.1016/j.foodchem.2023.136457
https://doi.org/10.1016/j.foodchem.2023.136457
Publikováno v:
Biologicals : journal of the International Association of Biological Standardization. 71
Xenogenic cell-based therapeutic products are expected to alleviate the chronic shortage of human donor organs. For example, porcine islet cell products are currently under development for the treatment of human diabetes. As porcine cells possess end
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eb7e9709985617f75383408361e84e2
https://pubmed.ncbi.nlm.nih.gov/34039532
https://pubmed.ncbi.nlm.nih.gov/34039532
Publikováno v:
Academic Journal of Medicine & Health Sciences. 2
In order to improve the targeting of doxorubicin and prolong the action time of the drug, we synthesized a pH-responsive PEG-Schiff-DOX polymer prodrug loaded with nanoparticles. The nanoparticles were prepared by synthesis of PEG-CHO and condensatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b7fca52c32abfc2a1dcc180eb651488
https://doi.org/10.25236/ajmhs.2021.020113
https://doi.org/10.25236/ajmhs.2021.020113
Autor:
Yu Liu, Julin Li, Zhongqiao Yun, Peibin Zeng, Hua Shan, Simone A. Glynn, Xiaoming Guo, Paul M. Ness, Jane Schulmann, Jingxing Wang, Guoxin Wen, Tonghan Yang, Yi Huang, J. Brooks Jackson, Yuzhe Yuan, Miao He
Publikováno v:
Transfusion. 52:1041-1049
BACKGROUND: The global human immunodeficiency virus (HIV)-1 epidemic is becoming increasingly diverse and complex. Molecular epidemiologic characteristics were studied for HIV-1–infected blood donors from five Chinese regions to determine genotype
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3158a49dd8b901992f527fc3a0346d4f
https://doi.org/10.1111/j.1537-2995.2011.03415.x
https://doi.org/10.1111/j.1537-2995.2011.03415.x
Autor:
Yuzhe Yuan, Hiromi Terasawa, Kazuaki Monde, Yosuke Maeda, Yusuke Nakano, Keisuke Yusa, Shinji Harada
Publikováno v:
Virology.
Bimolecular fluorescence complementation (BiFC) and western blot analysis demonstrated that CCR5 exists as constitutive homo-oligomers, which was further enhanced by its antagonists such as maraviroc (MVC) and TAK-779. Staining by monoclonal antibodi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bc1dd0f4cef8a2b2d2e0fb8691142ef
https://pubmed.ncbi.nlm.nih.gov/24606688
https://pubmed.ncbi.nlm.nih.gov/24606688