Zobrazeno 1 - 10
of 510
pro vyhledávání: '"Yuzhang Wu"'
Autor:
Zhiyuan Wei, Jian Zhou, Jie Shen, Dong Sun, Tianbao Gao, Qin Liu, Hongri Wu, Xiaohua Wang, Shulin Wang, Shiyu Xiao, Chao Han, Di Yang, Hui Dong, Yuzhang Wu, Yi Zhang, Shuai Xu, Xian Wang, Jie Luo, Qijie Dai, Jun Zhu, Sien Lin, Fei Luo, Yi Tian, Zhao Xie
Publikováno v:
Journal of Orthopaedic Translation, Vol 47, Iss , Pp 144-160 (2024)
Background: Osteomyelitis (OM) is an inflammatory condition of bone characterized by cortical bone devascularization and necrosis. Dysregulation of bone remodelling is triggered by OM. Bone remodelling is precisely coordinated by bone resorption and
Externí odkaz:
https://doaj.org/article/6c50044f2d444c0abdbd04ebaaf824da
Autor:
Lingxin Meng, Yue Pan, Yueping Liu, Rui He, Yuting Sun, Chenhui Wang, Lei Fei, Airu Zhu, Zhongfang Wang, Yunfei An, Yuzhang Wu, Bo Diao, Yongwen Chen
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundNatural infection or vaccination have provided robust immune defense against SARS-CoV-2 invasion, nevertheless, Omicron variants still successfully cause breakthrough infection, and the underlying mechanisms are poorly understood.MethodsSeq
Externí odkaz:
https://doaj.org/article/8a7a9809d5e4403695791c36fe3b9a96
Autor:
Ling Chang, Zihan Zheng, Yiwen Zhou, Kun Liu, Yinong Li, Bing Zhong, Zihua Zhao, Chengshun Chen, Can Qian, Qingshan Ni, Qinghua Zou, Yuzhang Wu, Jingyi Li, Liyun Zou
Publikováno v:
Arthritis Research & Therapy, Vol 26, Iss 1, Pp 1-11 (2024)
Abstract Background Primary Sjogren’s syndrome (pSS) is a complex autoimmune disease featuring damage to salivary and lacrimal glands, with the possibility of manifestations across multiple organs. Antibody-producing B cells have long been apprecia
Externí odkaz:
https://doaj.org/article/2f6739cb9d5e4580a6fc284c71aaa2d8
Autor:
Jie Zhao, Chen Yao, Yongqin Qin, Hanyong Zhu, Hui Guo, Binbin Ji, Xueqin Li, Na Sun, Rongqing Li, Yuzhang Wu, Kuiyang Zheng, Yuchen Pan, Tingting Zhao, Jing Yang
Publikováno v:
Cell Death and Disease, Vol 15, Iss 2, Pp 1-12 (2024)
Abstract Targeting C5aR1 modulates the function of infiltrated immune cells including tumor-associated macrophages (TAMs). The gut microbiome plays a pivotal role in colorectal cancer (CRC) tumorigenesis and development through TAM education. However
Externí odkaz:
https://doaj.org/article/d372a906775b4440b17e6178767adb6b
Autor:
Xian Wang, Chao Han, Di Yang, Jian Zhou, Hui Dong, Zhiyuan Wei, Shuai Xu, Chen Xu, Yiwei Zhang, Yi Sun, Bing Ni, Sheng Guo, Jingbo Zhang, Tingting Zhao, Xiangmei Chen, Jie Luo, Yuzhang Wu, Yi Tian
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-10 (2024)
Abstract Retinoid-related orphan receptor gamma t (RORγt) is the lineage-specific transcription factor for T helper 17 (Th17) cells. Our previous study demonstrated that STAT3 likely participates in the activation of RORCE2 (a novel enhancer of the
Externí odkaz:
https://doaj.org/article/cc89d00d7f124079800da8b82fff0065
Autor:
Peng Yu, Jingping Ran, Ruiqi Yang, Hang Zhu, Song Lu, Yuzhang Wu, Tingting Zhao, Tianchen Xiong
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionThe emergence of SARS-CoV-2 Omicron subvariants has presented a significant challenge to global health, as these variants show resistance to most antibodies developed early in the pandemic. Therapeutic antibodies with potent efficacy to t
Externí odkaz:
https://doaj.org/article/b3f51cc9375f432fa6f7accf1aa604f1
Autor:
Xiaojing Yang, Xichan Chen, Wei Wang, Siming Qu, Binbin Lai, Ji Zhang, Jian Chen, Chao Han, Yi Tian, Yingbin Xiao, Weiwu Gao, Yuzhang Wu
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Thymus is the main immune organ which is responsible for the production of self-tolerant and functional T cells, but it shrinks rapidly with age after birth. Although studies have researched thymus development and involution in mouse, the critical re
Externí odkaz:
https://doaj.org/article/ce8114d9e36f49e393475608d3e28b4d
Autor:
Jingxue Wang, Qian Liu, Yiwen Zhou, Chunhao Cao, Penghui Chen, Gang Meng, Ji Zhang, Xiaojuan Xin, Guangyu Huang, Yuzhang Wu
Publikováno v:
iScience, Vol 27, Iss 1, Pp 108723- (2024)
Summary: The NACHT, LRR, and PYD domains-containing protein 3 (NLRP3) inflammasome has been involved in the pathogenesis of various chronic liver diseases. However, its role in hepatitis B virus (HBV)-associated hepatitis remains unknown. Here we dem
Externí odkaz:
https://doaj.org/article/7be47dd04e224b339a0bbcfff220a7f5
Autor:
Jie Zhou, Guanming Chen, Jiuling Wang, Bo Zhou, Xuemin Sun, Jinsong Wang, Shu Tang, Xiangju Xing, Xiaofei Hu, Yang Zhao, Yu Peng, Wenjiong Shi, Tingting Zhao, Yuzhang Wu, Hanbing Zhong, Ni Hong, Zhihua Ruan, Yi Zhang, Wenfei Jin
Publikováno v:
Oncogenesis, Vol 12, Iss 1, Pp 1-9 (2023)
Abstract Anti-PD-1 therapy has shown promising outcomes in the treatment of different types of cancer. It is of fundamental interest to analyze the efficacy of anti-PD-1 therapy in cancer patients infected with hepatitis B virus (HBV) since the comor
Externí odkaz:
https://doaj.org/article/a85e1700f48d4b7490586b6f4c42becf
Autor:
Jinsong Wang, Debao Li, Bo Tang, Xuemin Sun, Wenjiong Shi, Hao Li, Zhenhua Zhang, Yuzhang Wu, Yi Zhang, Qinghua Qiao
Publikováno v:
Immunity, Inflammation and Disease, Vol 11, Iss 9, Pp n/a-n/a (2023)
Abstract Background The outbreak of coronavirus disease 2019 (COVID‐19) caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) has posed a great threat to human health. Some severe COVID‐19 patients still carried detectable le
Externí odkaz:
https://doaj.org/article/6852511798404a6dbd5e9908b4263e02