Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Yuyao Yuan"'
Autor:
Zhe Zhou, Di Dong, Yuyao Yuan, Juan Luo, Xiao-Ding Liu, Long-Yun Chen, Guangxi Wang, Yuxin Yin
Publikováno v:
EBioMedicine, Vol 109, Iss , Pp 105389- (2024)
Summary: Background: Metabolic reprogramming plays a pivotal role in cancer progression, contributing to substantial intratumour heterogeneity and influencing tumour behaviour. However, a systematic characterization of metabolic heterogeneity across
Externí odkaz:
https://doaj.org/article/82db8245e59a4b12b9025be6a05f2489
Autor:
Huajie Song, Xiaowei Tang, Miao Liu, Guangxi Wang, Yuyao Yuan, Ruifang Pang, Chenyi Wang, Juntuo Zhou, Yang Yang, Mengmeng Zhang, Yan Jin, Kewei Jiang, Shu Wang, Yuxin Yin
Publikováno v:
iScience, Vol 27, Iss 9, Pp 110682- (2024)
Summary: Reliable blood-based tests for identifying early-stage breast cancer remain elusive. Employing single-cell transcriptomic sequencing analysis, we illustrate a close correlation between nucleotide metabolism in the breast cancer and activatio
Externí odkaz:
https://doaj.org/article/7fcbde94248a4e3c808ac810dc650001
Publikováno v:
Foods, Vol 13, Iss 21, p 3494 (2024)
Postharvest grapes exhibit a limited shelf life due to susceptibility to rot and deterioration, significantly reducing their nutritional and economic value. Sulfur dioxide (SO2) is a widely recognized preservative for extending grape storage life. Th
Externí odkaz:
https://doaj.org/article/931606a210d243d5b605ab0d7b7f62aa
Autor:
Zhenyu Zhu, Zeliang Yang, Chuanda Zhu, Zixi Hu, Zhongyu Jiang, Jingjing Gong, Yuyao Yuan, Xi Chen, Yan Jin, Yuxin Yin
Publikováno v:
iScience, Vol 26, Iss 8, Pp 107367- (2023)
Summary: Immune checkpoint blockade has become an effective approach to reverse the immune tolerance of tumor cells. Indoleamine 2,3-dioxygenase 1 (IDO1) is frequently upregulated in many types of cancers and contributes to the establishment of an im
Externí odkaz:
https://doaj.org/article/1da277ec74c94f9b96593c8abbe9cf8e
Autor:
Juntuo Zhou, Nan Ji, Guangxi Wang, Yang Zhang, Huajie Song, Yuyao Yuan, Chunyuan Yang, Yan Jin, Zhe Zhang, Liwei Zhang, Yuxin Yin
Publikováno v:
EBioMedicine, Vol 81, Iss , Pp 104097- (2022)
Summary: Background: Most malignant brain gliomas (MBGs) are associated with dismal outcomes, mainly due to their late diagnosis. Current diagnostic methods for MBGs are based on imaging and histological examination, which limits their early detectio
Externí odkaz:
https://doaj.org/article/c888254d669f45f4b55343d3010490cb
Autor:
Xianling, Ning, Hailong, Qi, Yuyao, Yuan, Ridong, Li, Yuanyuan, Wang, Zhiqiang, Lin, Yuxin, Yin
Publikováno v:
European journal of pharmacology. 934
Ferroptosis is a non-apoptotic cell death characterized by iron-mediated ROS accumulation and increasing lipid peroxidation. The activation of ferroptosis results in the destruction of cancer cells and overcoming the drug resistance associated with e
Autor:
Yuyao Yuan, Juntuo Zhou, Guangxi Wang, Jianyuan Luo, Yongmei Song, Huajie Song, Zitong Zhao, Liyan Xue, Yuxin Yin, Pang Ruifang
Publikováno v:
Br J Cancer
Background Oesophageal cancer (EC) ranks high in both morbidity and mortality. A non-invasive and high-sensitivity diagnostic approach is necessary to improve the prognosis of EC patients. Methods A total of 525 serum samples were subjected to lipido
Autor:
Guangxi Wang, Hantao Yao, Yan Gong, Zipeng Lu, Ruifang Pang, Yang Li, Yuyao Yuan, Huajie Song, Jia Liu, Yan Jin, Yongsu Ma, Yinmo Yang, Honggang Nie, Guangze Zhang, Zhu Meng, Zhe Zhou, Xuyang Zhao, Mantang Qiu, Zhicheng Zhao, Kuirong Jiang, Qiang Zeng, Limei Guo, Yuxin Yin
Publikováno v:
Science Advances
Description
The machine learning–aided serum lipidomics approach could be used to help early diagnosis of patients with PDAC.
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers, characterized by rapid progression, m
The machine learning–aided serum lipidomics approach could be used to help early diagnosis of patients with PDAC.
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers, characterized by rapid progression, m
Autor:
Fan Mei, Jiapan Hu, Zhongyan Wu, Guangze Zhang, Anhang Liu, Xiang Li, Minglu Zhu, Yangyang Gan, Ling Liang, Xuyang Zhao, Yuyao Yuan, Xiangyan Meng, Yang Li, Yan Jin, Jianping Jia, Yuxin Yin
Publikováno v:
Cell reports. 40(3)
Synapse loss and memory decline are the primary features of neurodegenerative dementia. However, the molecular underpinnings that drive memory loss remain largely unknown. Here, we report that FAM69C is a kinase critically involved in neurodegenerati
Publikováno v:
The FASEB Journal. 35
Neural cells are continuously subjected to oxidative stress arising from electrochemical activity, and cellular protection systems can turn on the oxidative stress response to detect and alleviate adverse conditions. However, the function and mechani