Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Yuya Ogata"'
Autor:
Kaho Arikawa, Seiken Tokura, Ryo Takahashi, Kosuke Kanuma, Tomoko Abe-Kumasaka, Hiroyuki Sugiyama, Toru Yamaguchi-Sasaki, Yutaka Sugaya, Yuya Ogata, Takanori Kawaguchi, Ippei Yoshida, Kanako Iwakiri
Publikováno v:
ACS Med Chem Lett
[Image: see text] A novel series of macrocyclic pyrazolo[1,5-a]pyrimidine derivatives as respiratory syncytial virus (RSV) fusion glycoprotein (F protein) inhibitors were designed and synthesized based on docking studies of acyclic inhibitors. This e
Autor:
Yuya Ogata, Jun Kurosaka, Ryo Takahashi, Yutaka Sugaya, Eiji Tanigawa, Hiroyuki Sugiyama, Kosuke Kanuma, Kanako Iwakiri, Toru Yamaguchi-Sasaki, Tomoko Abe-Kumasaka, Naoko Ueda-Yonemoto, Yunoshin Tamura, Takanori Kawaguchi, Tsuyoshi Busujima
Publikováno v:
Chemical and Pharmaceutical Bulletin. 68:345-362
Respiratory syncytial virus (RSV) is one of the most common causes of lower respiratory tract infections and a significant pathogen for both adults and children. Although two drugs have been approved for the treatment of RSV infections, the low thera
Autor:
Yuya Ogata, Harumi Kanazawa, Macias Alba, Norikazu Ohtake, Allan E. Surgenor, Iichiro Takata, Hajime Takashima, Walmsley David, Kiyoko Fujita, Hayley Angove, Kunihiko Iwamoto, Masashi Mima, Hiroyuki Sugiyama, Fumihito Ushiyama, Junya Yamagishi, Yousuke Yamada, Alan P. Robertson, Kosuke Hitaka, Koichiro Nakano, Hayato Watanabe, Atsushi Okada, Yohei Matsuda, Roderick E. Hubbard, Nozomi Tanaka-Yamamoto, Toru Yamaguchi-Sasaki, Risa Kurimoto-Tsuruta, Lisa Baker, Akihiro Tanaka, R. Harris
Publikováno v:
Journal of medicinal chemistry. 63(23)
UDP-3-O-acyl-N-acetylglucosamine deacetylase (LpxC) is a zinc metalloenzyme that catalyzes the first committed step in the biosynthesis of Lipid A, an essential component of the cell envelope of Gram-negative bacteria. The most advanced, disclosed Lp
Autor:
Yuya Ogata, Nozomi Tanaka-Yamamoto, Naoki Sasamoto, Iichiro Takata, Katsumasa Otake, Hajime Takashima, Yohei Matsuda, Haruhiro Yamashita, Mayumi Endo, Kiyoko Fujita, Kaori Ueki, Masashi Mima, Satoshi Tsuji, Hirotoshi Okumura, Hiroyuki Sugiyama, Fumihito Ushiyama, Risa Kurimoto-Tsuruta
Publikováno v:
Bioorganicmedicinal chemistry. 30
Infectious diseases caused by resistant Gram-negative bacteria have become a serious problem, and the development of therapeutic drugs with a novel mechanism of action and that do not exhibit cross-resistance with existing drugs has been earnestly de
Publikováno v:
Energies; Volume 13; Issue 1; Pages: 57
We propose a paper solar cell based on carbon nanotube (CNT)-composite papers. To fabricate this cell, we use dye-sensitized solar cells (DSCs) for generating power through the redox reaction of dyes in conjunction with CNT-composite papers, which ar
Autor:
Risa Kurimoto-Tsuruta, Seiken Tokura, Kosuke Kanuma, Yuya Ogata, Tamaoki Tomokazu, Hiroyuki Sugiyama, Takanori Kawaguchi, Kaho Arikawa, Takeuchi Tomoki, Nozomi Tanaka-Yamamoto, Toru Yamaguchi-Sasaki, Atsushi Okada, Ippei Yoshida, Tomoko Abe-Kumasaka, Yutaka Sugaya, Ryo Takahashi, Mitsukane Yoshinaga
Publikováno v:
Bioorganic & Medicinal Chemistry. 28:115818
The development of effective respiratory syncytial virus (RSV) fusion glycoprotein (F protein) inhibitors against both wild-type and the D486N-mutant F protein is urgently required. We recently reported a 15-membered macrocyclic pyrazolo[1,5-a]pyrimi
Publikováno v:
Diamond and Related Materials. 101:107602
Long-time chemical vapor deposition (CVD) with ethanol was carried out for the growth of graphene films on copper (Cu) foils. Multilayer graphene like graphite is formed on Cu surface. Interestingly, some pits with unique shapes are produced at defec
Autor:
Rei Sagawa, Kyosuke Woo, Miki Ikezawa, Yuya Ogata, Haruka Tohge, Haruna Okamoto, Rintaro Okada, Takahiro Chiba
Publikováno v:
AMA Summer Academic Conference Proceedings; 2019, Vol. 30, pAOP-16-AOP-21, 6p
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 22(20)
We have described in detail the total synthesis of both the proposed and correct structures of (−)-lyngbyaloside B, which facilitated the elucidation of the complete stereostructure of this natural product. Our study began with the total synthesis
Publikováno v:
Chemistry - A European Journal. 22:6701-6701