Zobrazeno 1 - 10
of 238
pro vyhledávání: '"Yuya Kondo"'
Autor:
Yuki Ishikawa, Nao Tanaka, Yoshihide Asano, Masanari Kodera, Yuichiro Shirai, Mitsuteru Akahoshi, Minoru Hasegawa, Takashi Matsushita, Kazuyoshi Saito, Sei-ichiro Motegi, Hajime Yoshifuji, Ayumi Yoshizaki, Tomohiro Kohmoto, Kae Takagi, Akira Oka, Miho Kanda, Yoshihito Tanaka, Yumi Ito, Kazuhisa Nakano, Hiroshi Kasamatsu, Akira Utsunomiya, Akiko Sekiguchi, Hiroaki Niiro, Masatoshi Jinnin, Katsunari Makino, Takamitsu Makino, Hironobu Ihn, Motohisa Yamamoto, Chisako Suzuki, Hiroki Takahashi, Emi Nishida, Akimichi Morita, Toshiyuki Yamamoto, Manabu Fujimoto, Yuya Kondo, Daisuke Goto, Takayuki Sumida, Naho Ayuzawa, Hidetoshi Yanagida, Tetsuya Horita, Tatsuya Atsumi, Hirahito Endo, Yoshihito Shima, Atsushi Kumanogoh, Jun Hirata, Nao Otomo, Hiroyuki Suetsugu, Yoshinao Koike, Kohei Tomizuka, Soichiro Yoshino, Xiaoxi Liu, Shuji Ito, Keiko Hikino, Akari Suzuki, Yukihide Momozawa, Shiro Ikegawa, Yoshiya Tanaka, Osamu Ishikawa, Kazuhiko Takehara, Takeshi Torii, Shinichi Sato, Yukinori Okada, Tsuneyo Mimori, Fumihiko Matsuda, Koichi Matsuda, Tiffany Amariuta, Issei Imoto, Keitaro Matsuo, Masataka Kuwana, Yasushi Kawaguchi, Koichiro Ohmura, Chikashi Terao
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Here we report the largest Asian genome-wide association study (GWAS) for systemic sclerosis performed to date, based on data from Japanese subjects and comprising of 1428 cases and 112,599 controls. The lead SNP is in the FCGR/FCRL region,
Externí odkaz:
https://doaj.org/article/2821292baef747248e9e487cef06ad07
Autor:
Yuya Kondo, Saori Abe, Hirofumi Toko, Tomoya Hirota, Hiroyuki Takahashi, Masaru Shimizu, Hisashi Noma, Hiroto Tsuboi, Isao Matsumoto, Toshiro Inaba, Takayuki Sumida
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract The aim of this study was to clarify the effect of climatic environment on the immunological features of rheumatoid arthritis (RA). Blood samples were collected from patients with RA and healthy controls (HCs), matched by age and sex, living
Externí odkaz:
https://doaj.org/article/c7f40c82d42a4963b2581f4fedf289ca
Autor:
Mizuki Yagishita, Hiroto Tsuboi, Yuki Kuroda, Tomonori Sawabe, Akira Kawashima, Fumina Kawashima, Nana Uematsu, Ryota Sato, Taihei Nishiyama, Mayu Terasaki, Hirofumi Toko, Fumika Honda, Ayako Ohyama, Saori Abe, Ayako Kitada, Haruka Miki, Shinya Hagiwara, Yuya Kondo, Takayuki Sumida, Isao Matsumoto
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract Recent studies have suggested that the clinical features of elderly-onset adult-onset Still’s disease (AOSD) differ from those of young and middle-aged-onset patients, whereas the details remain unclear, and cytokine profiles of elderly-on
Externí odkaz:
https://doaj.org/article/595b3e9840a24690a52cdd696d0745d9
Autor:
Takayuki Sumida, Aya Kawasaki, Hiroshi Hashimoto, Naoyuki Tsuchiya, Isao Matsumoto, Yuya Kondo, Hirofumi Amano, Naoto Tamura, Premita Ari Kusumawati, Yuka Kawamura, Makio Kusaoi, Yasuyoshi Kusanagi, Kenji Itoh, Takashi Fujimoto
Publikováno v:
RMD Open, Vol 9, Iss 2 (2023)
Objective Major histocompatibility complex strongly contributes to susceptibility to systemic lupus erythematosus (SLE). In the European populations, HLA-DRB1*03:01 and DRB1*15:01 are susceptibility alleles, but C4 locus was reported to account for t
Externí odkaz:
https://doaj.org/article/7da6d1da06454ed482299aaf0e3ef8dd
Autor:
Fumika Honda, Hiroto Tsuboi, Yuko Ono, Saori Abe, Hiroyuki Takahashi, Kiyoaki Ito, Kazunori Yamada, Mitsuhiro Kawano, Yuya Kondo, Kenichi Asano, Masato Tanaka, Marie Malissen, Bernard Malissen, Isao Matsumoto, Takayuki Sumida
Publikováno v:
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-12 (2021)
Abstract Background Our previous studies reveal that CCL18-CCR8 chemokine axis is upregulated in patients of immunoglobulin G4-related disease (IgG4-RD), suggesting that the CCL18–CCR8 axis is implicated in the etiology of IgG4-RD, although whether
Externí odkaz:
https://doaj.org/article/c11881d6588845c0bb000ce1e7a6f232
Autor:
Masaru Shimizu, Yuya Kondo, Reona Tanimura, Kotona Furuyama, Masahiro Yokosawa, Hiromitsu Asashima, Hiroto Tsuboi, Isao Matsumoto, Takayuki Sumida
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract T-bet is a key transcription factor for the T helper 1 lineage and its expression level is negatively correlated to inflammation in patients with rheumatoid arthritis (RA). Our previous study using T-bet transgenic mice revealed over-express
Externí odkaz:
https://doaj.org/article/56b7d7675fa54ce8b1d120d5097ca7c5
Autor:
Hiroto Tsuboi, Seiji Segawa, Mizuki Yagishita, Hirofumi Toko, Fumika Honda, Ayako Kitada, Haruka Miki, Ayako Ohyama, Shinya Hagiwara, Yuya Kondo, Isao Matsumoto, Takayuki Sumida
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Adult onset Still disease (AOSD) is a systemic inflammatory disorder characterized by skin rash, spiking fever, arthritis, sore throat, lymphadenopathy, and hepatosplenomegaly. Although the etiology of this disease has not been fully clarified, both
Externí odkaz:
https://doaj.org/article/5012c71139a745769f0cae9037c1946a
Autor:
Tsukasa Sasoh, Hirona Kugo, Yuya Kondo, Kento Miyamoto, Momoka Minami, Mayo Higashihara, Hirokazu Kawamoto, Fumiaki Takeshita, Tatsuya Moriyama, Nobuhiro Zaima
Publikováno v:
Adipocyte, Vol 10, Iss 1, Pp 412-423 (2021)
Vascular diseases such as atherosclerosis and aneurysms are associated with diet. Perivascular adipose tissue (PVAT) was reportedly involved in the regulation of vascular functions. It is suggested that imbalanced diets can cause PVAT inflammation an
Externí odkaz:
https://doaj.org/article/fdd12bc9d8b34487a51d10226c1f6232
Autor:
Fumio Matsuda, Kousuke Maeda, Takeo Taniguchi, Yuya Kondo, Futa Yatabe, Nobuyuki Okahashi, Hiroshi Shimizu
Publikováno v:
Metabolic Engineering Communications, Vol 13, Iss , Pp e00177- (2021)
13C-based metabolic flux analysis (13C-MFA) is an essential tool for estimating intracellular metabolic flux levels in metabolic engineering and biology. In 13C-MFA, a metabolic flux distribution that explains the observed isotope labeling data was c
Externí odkaz:
https://doaj.org/article/7b89c38c628645b7977410b088a13e6e
Autor:
Hoshimi Kawaguchi, Isao Matsumoto, Atsumu Osada, Izumi Kurata, Hiroshi Ebe, Yuki Tanaka, Asuka Inoue, Naoto Umeda, Yuya Kondo, Hiroto Tsuboi, Yasuhiro Shinkai, Yoshito Kumagai, Akihito Ishigami, Takayuki Sumida
Publikováno v:
Arthritis Research & Therapy, Vol 20, Iss 1, Pp 1-13 (2018)
Abstract Background Anticitrullinated protein antibodies (ACPA) and citrullinated proteins play key roles in the pathogenesis of rheumatoid arthritis (RA). Many candidate citrullinated antigens have been identified in joints, but citrullinated protei
Externí odkaz:
https://doaj.org/article/20feb786dc80465183bc98285a82a06e