Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Yuya Horinouchi"'
Autor:
Fuka Aizawa, Hirofumi Hamano, Naoto Okada, Kenta Yagi, Mitsuhiro Goda, Hideki Nawa, Yuya Horinouchi, Toshimi Nakamura, Harumasa Hakuno, Kazuaki Shinomiya, Yoshito Zamami, Masahiko Azuma, Masashi Akaike, Keisuke Ishizawa
Publikováno v:
Journal of Pharmaceutical Health Care and Sciences, Vol 10, Iss 1, Pp 1-9 (2024)
Abstract Background Understanding the roles and competencies of professions outside of one’s specialty is essential for providing efficient healthcare. However, it is difficult for medical professionals to understand the roles and competencies of o
Externí odkaz:
https://doaj.org/article/1385a6b4656e49b9840569b013cf42bd
Autor:
Tatsuya Tsuda, Masaki Imanishi, Mizuho Oogoshi, Mitsuhiro Goda, Yoshitaka Kihira, Yuya Horinouchi, Yoshito Zamami, Keisuke Ishizawa, Yasumasa Ikeda, Ichiro Hashimoto, Toshiaki Tamaki, Yuki Izawa-Ishizawa
Publikováno v:
Journal of Pharmacological Sciences, Vol 142, Iss 3, Pp 109-115 (2020)
Arterial calcification, a risk factor of cardiovascular events, develops with differentiation of vascular smooth muscle cells (VSMCs) into osteoblast-like cells. Cyclophilin A (CypA) is a peptidyl-prolyl isomerase involved in cardiovascular diseases
Externí odkaz:
https://doaj.org/article/94345c65ddb44ed0b26ff8fc9aff9134
Autor:
Keisuke Ishizawa, Kunihisa Yamaguchi, Yuya Horinouchi, Yayoi Fukuhara, Soichiro Tajima, Shuichi Hamano, Shuhei Tomita, Koichiro Tsuchiya, Toshiaki Tamaki
Publikováno v:
Journal of Pharmacological Sciences, Vol 109, Iss 1, Pp 14-19 (2009)
Chronic kidney disease (CKD) is becoming a major public health problem worldwide. It is important to protect endothelial function in CKD treatment because injury of the endothelium is a critical event for the generation and progression of CKD. Recent
Externí odkaz:
https://doaj.org/article/fb4e0cfa7a6840d08a7e86a58ebfb60f
Autor:
Yasumasa Ikeda, Iori Ozono, Soichiro Tajima, Mizuki Imao, Yuya Horinouchi, Yuki Izawa-Ishizawa, Yoshitaka Kihira, Licht Miyamoto, Keisuke Ishizawa, Koichiro Tsuchiya, Toshiaki Tamaki
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89355 (2014)
Renal fibrosis plays an important role in the onset and progression of chronic kidney diseases (CKD). Although several mechanisms underlying renal fibrosis and candidate drugs for its treatment have been identified, the effect of iron chelator on ren
Externí odkaz:
https://doaj.org/article/e0b37a223a874e80ac041f20dfee1b51
Autor:
Takahiro Niimura, Mitsuhiro Goda, Michiko Yamashita, Koichiro Tsuchiya, Keisuke Ishizawa, Hiromichi Fujino, Yasumasa Ikeda, Seiji Kishi, Toshiaki Tamaki, Masaki Imanishi, Hirofumi Hamano, Yoshito Zamami, Yuki Izawa-Ishizawa, Kenshi Takechi, Ken-ichi Aihara, Licht Miyamoto, Yuya Horinouchi, Masayuki Chuma, Keijo Fukushima
Publikováno v:
Kidney International. 99:885-899
Cisplatin is widely used as an anti-tumor drug for the treatment of solid tumors. Unfortunately, it causes kidney toxicity as a critical side effect, limiting its use, given that no preventive drug against cisplatin-induced kidney toxicity is current
Autor:
Yuya Horinouchi, Yuka Murashima, Yuto Yamada, Shun Yoshioka, Keijo Fukushima, Takumi Kure, Naofumi Sasaki, Masaki Imanishi, Hiromichi Fujino, Koichiro Tsuchiya, Kazuaki Shinomiya, Yasumasa Ikeda
Publikováno v:
Life Sciences. 321:121590
Autor:
Takahiro Niimura, Masayuki Chuma, Keisuke Ishizawa, Yuya Horinouchi, Takahiro Shibata, Yuki Izawa-Ishizawa, Takumi Sakurada, Hirofumi Hamano, Shunsuke Ishida, Naoto Okada, Yasumasa Ikeda, Kimiko Fukunaga, Marin Mitstui, Hiroaki Yanagawa, Mitsuhiro Goda, Kenta Yagi, Yoshito Zamami
Publikováno v:
Cancer Medicine
Background In patients treated with bevacizumab, hypertension may be a biomarker of therapeutic efficacy. However, it is not clear whether drugs that control blood pressure influence bevacizumab's efficacy. In this study, we investigated drugs that m
Autor:
Tetsuya Shiuchi, Yasumasa Ikeda, Hiroaki Watanabe, Keisuke Ishizawa, Mitsuhiro Goda, Ken-ichi Aihara, Masaki Imanishi, Yoshito Zamami, Koichiro Tsuchiya, Toshiaki Tamaki, Licht Miyamoto, Kenshi Takechi, Hirofumi Hamano, Yuya Horinouchi, Yuki Izawa-Ishizawa
Publikováno v:
Diabetologia. 63:1588-1602
Iron accumulation affects obesity and diabetes, both of which are ameliorated by iron reduction. Ferritin, an iron-storage protein, plays a crucial role in iron metabolism. H-ferritin exerts its cytoprotective action by reducing toxicity via its ferr
Autor:
Yasumasa Ikeda, Masayuki Chuma, Yuki Izawa-Ishizawa, Masatoshi Kishuku, Keijo Fukushima, Raiki Ikuto, Kenshi Takechi, Yusuke Yamakawa, Koichi Tsuneyama, Masateru Kondo, Akiko Maegawa, Mitsuhiro Goda, Hiromichi Fujino, Yoshito Zamami, Keisuke Ishizawa, Masaki Imanishi, Yuya Horinouchi, Koichiro Tsuchiya
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 393:1239-1250
The roles of cancer-associated fibroblasts (CAFs) have been studied in the tumor progression, and CAFs are expected to become the new targets for cancer pharmacotherapies. CAFs contribute to tumor cell survival and proliferation, tumor angiogenesis,
Autor:
Yasumasa Ikeda, Yoshitaka Kihira, Toshiaki Tamaki, Tatsuya Tsuda, Yuki Izawa-Ishizawa, Mitsuhiro Goda, Keisuke Ishizawa, Mizuho Oogoshi, Masaki Imanishi, Yoshito Zamami, Ichiro Hashimoto, Yuya Horinouchi
Publikováno v:
Journal of Pharmacological Sciences, Vol 142, Iss 3, Pp 109-115 (2020)
Arterial calcification, a risk factor of cardiovascular events, develops with differentiation of vascular smooth muscle cells (VSMCs) into osteoblast-like cells. Cyclophilin A (CypA) is a peptidyl-prolyl isomerase involved in cardiovascular diseases