Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Yuxiu C. Xia"'
Autor:
Qianyu Chen, Shenna Langenbach, Meina Li, Yuxiu C. Xia, Xumei Gao, Matthew J. Gartner, Elizabeth A. Pharo, Sinéad M. Williams, Shawn Todd, Nadeene Clarke, Sarath Ranganathan, Michelle L. Baker, Kanta Subbarao, Alastair G. Stewart
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Coronavirus disease 2019 (COVID-19) caused by infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an acute respiratory disease with systemic complications. Therapeutic strategies for COVID-19, including repurposing (par
Externí odkaz:
https://doaj.org/article/15b090cdb2724c8b98fce5382addcb78
Autor:
Meina Li, Christine R. Keenan, Guillermo Lopez-Campos, Jonathan E. Mangum, Qianyu Chen, Danica Prodanovic, Yuxiu C. Xia, Shenna Y. Langenbach, Trudi Harris, Vinzenz Hofferek, Gavin E. Reid, Alastair G. Stewart
Publikováno v:
iScience, Vol 12, Iss , Pp 232-246 (2019)
Summary: Impaired therapeutic responses to anti-inflammatory glucocorticoids (GC) in chronic respiratory diseases are partly attributable to interleukins and transforming growth factor β1 (TGF-β1). However, previous efforts to prevent induction of
Externí odkaz:
https://doaj.org/article/e7525d099b3949b8b7a1119709301e77
Autor:
Yuxiu C Xia, Asmaa Radwan, Christine R Keenan, Shenna Y Langenbach, Meina Li, Danica Radojicic, Sarah L Londrigan, Rosa C Gualano, Alastair G Stewart
Publikováno v:
PLoS Pathogens, Vol 13, Iss 1, p e1006138 (2017)
Asthma and chronic obstructive pulmonary disease (COPD) exacerbations are commonly associated with respiratory syncytial virus (RSV), rhinovirus (RV) and influenza A virus (IAV) infection. The ensuing airway inflammation is resistant to the anti-infl
Externí odkaz:
https://doaj.org/article/b9cd46f04e5549d29c4c18cf4aa78b16
Autor:
Yuxiu C. Xia, Shenna Y. Langenbach, Gavin E. Reid, Danica Prodanovic, Christine R. Keenan, Alastair G. Stewart, Trudi Harris, Guillermo Lopez-Campos, Meina Li, Qianyu Chen, Vinzenz Hofferek, Jonathan E. Mangum
Publikováno v:
iScience, Vol 12, Iss, Pp 232-246 (2019)
iScience
Li, M, Keenan, C R, Lopez Campos, G, Mangum, J E, Chen, Q, Prodanovic, D, Xia, Y C, Langenbach, S Y, Harris, T, Hofferek, V, Reid, G E & Stewart, A G 2019, ' A Non-canonical Pathway with Potential for Safer Modulation of Transforming Growth Factor-β1 in Steroid-Resistant Airway Diseases. ', iScience, vol. 12, pp. 232-246 . https://doi.org/10.1016/j.isci.2019.01.023
iScience
Li, M, Keenan, C R, Lopez Campos, G, Mangum, J E, Chen, Q, Prodanovic, D, Xia, Y C, Langenbach, S Y, Harris, T, Hofferek, V, Reid, G E & Stewart, A G 2019, ' A Non-canonical Pathway with Potential for Safer Modulation of Transforming Growth Factor-β1 in Steroid-Resistant Airway Diseases. ', iScience, vol. 12, pp. 232-246 . https://doi.org/10.1016/j.isci.2019.01.023
Summary Impaired therapeutic responses to anti-inflammatory glucocorticoids (GC) in chronic respiratory diseases are partly attributable to interleukins and transforming growth factor β1 (TGF-β1). However, previous efforts to prevent induction of G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9124f59c59b68c709d6bfade601eac93
https://doi.org/10.1016/j.isci.2019.01.023
https://doi.org/10.1016/j.isci.2019.01.023
Autor:
C. Boardman, L. Chachi, Mark M. Perry, A. Gavrila, Herman Meurs, Pawan K. Sharma, Christine R. Keenan, Yuxiu C. Xia
Publikováno v:
Pulmonary Pharmacology & Therapeutics, 29(2), 129-143. ACADEMIC PRESS LTD-ELSEVIER SCIENCE LTD
Glucocorticoids are the mainstay for the treatment of chronic inflammatory diseases including asthma and chronic obstructive pulmonary disease (COPD). However, it has been recognized that glucocorticoids do not work well in certain patient population
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4893242d7e9ce2e468f20e86acc4c75a
https://hdl.handle.net/11370/32c415f2-0996-4202-8367-dd3a6d3f8d5f
https://hdl.handle.net/11370/32c415f2-0996-4202-8367-dd3a6d3f8d5f
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. :PO4-5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e98ff7d5b0e3c5d96c6e79e9e7ce7574
https://doi.org/10.1254/jpssuppl.wcp2018.0_po4-5-11
https://doi.org/10.1254/jpssuppl.wcp2018.0_po4-5-11
Autor:
Yuxiu C. Xia, Michael Schuliga, Simon G. Royce, Trudi Harris, Alastair G. Stewart, John A. Hamilton
Publikováno v:
British Journal of Pharmacology. 170:1421-1435
Background and Purpose The conversion of plasminogen into plasmin by interstitial urokinase plasminogen activator (uPA) is potentially important in asthma pathophysiology. In this study, the effect of uPA-mediated plasminogen activation on airway smo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::030d626af0945b2945711d11ba80ffb4
https://doi.org/10.1111/bph.12422
https://doi.org/10.1111/bph.12422
Publikováno v:
Current Opinion in Pharmacology. 13:386-393
The plasminogen activation system (PAS) and the plasmin it forms have dual roles in chronic respiratory diseases including asthma, chronic obstructive pulmonary disease and interstitial lung disease. Whilst plasmin-mediated airspace fibrinolysis is b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abd3536b5633873e0b7407568349591e
https://doi.org/10.1016/j.coph.2013.05.014
https://doi.org/10.1016/j.coph.2013.05.014
Autor:
Chengxue Qin, Alastair G. Stewart, Trudi Harris, Blanca Camoretti-Mercado, Michael Schuliga, Xuehua Zhang, Yuxiu C. Xia, Zhexing Wang, Peter Vee Sin Lee, Aqeel Javeed
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 48:346-353
In asthma, basic fibroblast growth factor (FGF-2) plays an important (patho)physiological role. This study examines the effects of FGF-2 on the transforming growth factor–β (TGF-β)–stimulated differentiation of airway smooth muscle (ASM) cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05a0c4faaa19afb6daa92b2fde0aa8e9
https://doi.org/10.1165/rcmb.2012-0151oc
https://doi.org/10.1165/rcmb.2012-0151oc
Autor:
Alastair G. Stewart, Shenna Y. Langenbach, Meina Li, Yuxiu C. Xia, Danica Radojicic, Christine R. Keenan, Asmaa Radwan, Rosa C. Gualano, Sarah L. Londrigan
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 13, Iss 1, p e1006138 (2017)
PLoS Pathogens, Vol 13, Iss 1, p e1006138 (2017)
Asthma and chronic obstructive pulmonary disease (COPD) exacerbations are commonly associated with respiratory syncytial virus (RSV), rhinovirus (RV) and influenza A virus (IAV) infection. The ensuing airway inflammation is resistant to the anti-infl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ff702b4ea8ce77fbe73790e809b6b4d
https://pubmed.ncbi.nlm.nih.gov/28046097
https://pubmed.ncbi.nlm.nih.gov/28046097