Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Yuxin Mu"'
Autor:
Jian Zhang, Yiqun Du, Yanchun Meng, Xiaojun Liu, Yuxin Mu, Yunpeng Liu, Yehui Shi, Jufeng Wang, Aimin Zang, Shanzhi Gu, Tianshu Liu, Huan Zhou, Hongqian Guo, Silong Xiang, Xialu Zhang, Suqiong Wu, Huanhuan Qi, Mengke Li, Xichun Hu
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-9 (2024)
Abstract DP303c is a HER2-targeted ADC with a cleavable linker-MMAE payload. Previous in vitro studies demonstrated that DP303c showed similar or better antitumor activity than T-DM1 in xenograft models. This was a multicenter, dose escalation and do
Externí odkaz:
https://doaj.org/article/e373209687f84f2f8062a4819767885a
Publikováno v:
Thoracic Cancer, Vol 14, Iss 34, Pp 3381-3388 (2023)
Abstract Background The clinical characteristics and efficacy of human epidermal growth factor receptor‐2 (HER‐2)‐directed agents against HER2 mutations and HER2 fusions in breast cancer are obscure due to their low frequency. Methods We conduc
Externí odkaz:
https://doaj.org/article/0282f3452f7049af81f1f6ea3e1c0308
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-12 (2023)
Abstract Background The mammalian target of rapamycin (mTOR) kinase, a central component of the PI3K/AKT/mTOR pathway, plays a critical role in tumor biology as an attractive therapeutic target. We conducted this first-in-human study to investigate t
Externí odkaz:
https://doaj.org/article/0116ecedf75541d9827069d3e5bddbc2
Autor:
Junmeng Yuan, Fan Zhao, Yu Liu, Huawei Liu, Kai Zhang, Xinyu Tian, Yuxin Mu, Jinshan Zhao, Yang Wang
Publikováno v:
Poultry Science, Vol 102, Iss 12, Pp 103128- (2023)
ABSTRACT: Poultry meat has a high polyunsaturated fatty acids content, making it vulnerable to oxidative stress. Mitophagy participates in the regulation of oxidative stress and the nucleotide-binding and oligomerization domain (NOD)-like receptor fa
Externí odkaz:
https://doaj.org/article/801a44b13b5948eb9a45b1d411958a54
Autor:
Yan Li, Ziyi Xu, Shouzheng Wang, Yixiang Zhu, Di Ma, Yuxin Mu, Jianming Ying, Junling Li, Puyuan Xing
Publikováno v:
Thoracic Cancer, Vol 13, Iss 15, Pp 2201-2209 (2022)
Abstract Objective Circulating tumor DNA (ctDNA) monitoring proves to be a promising approach to assess response and predict survival in epidermal growth factor receptor (EGFR)‐mutated non‐small‐cell lung cancer (NSCLC) patients treated with ty
Externí odkaz:
https://doaj.org/article/ad3eca3928f2480b8cffeb240e6b29ef
Autor:
Hongge Liang, Xia Song, Yuhui Zhang, Shucai Zhang, Fang Li, Jian Fang, Junling Li, Li Liang, Ligong Nie, Kewei Ma, Liangming Zhang, Xiaohong Wang, Junjun Xu, Yanxia Wei, Jinghui Wang, Qi Song, Guangming Tian, Yuxin Mu, Yangchun Gu, Lei Yang, Ping Sun, Wei Zhong, Jing Zhao, Yan Xu, Minjiang Chen, Mengzhao Wang
Publikováno v:
Thoracic Cancer, Vol 10, Iss 7, Pp 1521-1532 (2019)
Background Tyrosine kinase inhibitors (TKIs) can significantly prolong overall survival for patients with advanced non‐small cell lung cancer (NSCLC) harboring epidermal growth factor receptor (EGFR)‐mutation or anaplastic lymphoma kinase (ALK)
Externí odkaz:
https://doaj.org/article/ad60baa3f8544daa82949c57425b382c
Publikováno v:
Thoracic Cancer, Vol 10, Iss 6, Pp 1461-1468 (2019)
Background Afatinib is an irreversible ErbB family blocker that improves progression‐free survival (PFS) of advanced EGFR‐mutant lung adenocarcinoma compared to chemotherapy. However, afatinib leads to more adverse events than first‐generation
Externí odkaz:
https://doaj.org/article/58ac1678a51347ab9e776849e10ceb4e
Autor:
Yuxin Mu, Ke Yang, Xuezhi Hao, Yan Wang, Lin Wang, Yutao Liu, Lin Lin, Junling Li, Puyuan Xing
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
BRAF mutation is an oncogenic driver gene in non-small cell lung cancer (NSCLC) with low frequency. The data of patients with NSCLC harboring BRAF mutations is rare. We conducted a retrospective multicenter study in Chinese patients with NSCLC harbor
Externí odkaz:
https://doaj.org/article/d53aef1d62b345128dae1cf333cc05ca
Autor:
Hongqiang Li, Zhixuan An, Shasha Zuo, Wei Zhu, Zhen Zhang, Shanshan Zhang, Cheng Zhang, Wenchao Song, Quanhua Mao, Yuxin Mu, Enbang Li, Juan Daniel Prades García
Publikováno v:
Sensors, Vol 21, Iss 18, p 6043 (2021)
Heart disease is the leading cause of death for men and women globally. The residual network (ResNet) evolution of electrocardiogram (ECG) technology has contributed to our understanding of cardiac physiology. We propose an artificial intelligence-en
Externí odkaz:
https://doaj.org/article/439ca7b95f794f4a859e939594a8ebb4
Autor:
Yan Li, Ziyi Xu, Shouzheng Wang, Yixiang Zhu, Di Ma, Yuxin Mu, Jianming Ying, Junling Li, Puyuan Xing
Publikováno v:
Thoracic Cancer. 13:2201-2209
Circulating tumor DNA (ctDNA) monitoring proves to be a promising approach to assess response and predict survival in epidermal growth factor receptor (EGFR)-mutated non-small-cell lung cancer (NSCLC) patients treated with tyrosine kinase inhibitors