Zobrazeno 1 - 10
of 187
pro vyhledávání: '"Yuxin, Liang"'
Autor:
Ashley Byrne, Daniel Le, Kostianna Sereti, Hari Menon, Samir Vaidya, Neha Patel, Jessica Lund, Ana Xavier-Magalhães, Minyi Shi, Yuxin Liang, Timothy Sterne-Weiler, Zora Modrusan, William Stephenson
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Single-cell RNA sequencing predominantly employs short-read sequencing to characterize cell types, states and dynamics; however, it is inadequate for comprehensive characterization of RNA isoforms. Long-read sequencing technologies enable si
Externí odkaz:
https://doaj.org/article/ea2115afd9f64a1e84e08c68a787dbc9
Autor:
Yingchao Tian, Xiu Chen, Jie Pu, Yuxin Liang, Weixi Li, Xiaotong Xu, Xinshui Tan, Shuntai Yu, Tianyu Shao, Yan Ma, Bingwei Wang, Yongjie Chen, Yushan Li
Publikováno v:
PLoS Genetics, Vol 20, Iss 7, p e1011357 (2024)
Hexokinase (HK) catalyzes the first irreversible rate-limiting step in glycolysis that converts glucose to glucose-6-phosphate. HK1 is ubiquitously expressed in the brain, erythrocytes, and other tissues where glycolysis serves as the major source of
Externí odkaz:
https://doaj.org/article/04de8b5ef5dd44c6948bed1378841c50
Autor:
Qiting Zeng, Jun He, Xiguang Chen, Qiong Yuan, Liyang Yin, Yuxin Liang, Xuyu Zu, Yingying Shen
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 176, Iss , Pp 116932- (2024)
Hematopoietic cell kinase (Hck), a non-receptor tyrosine kinase belonging to the Src kinase family, is intricately linked to the pathogenesis of numerous human diseases, with a particularly pronounced association with cancer. Hck not only directly im
Externí odkaz:
https://doaj.org/article/e92b13b877b441f3b5043e5fe3d97113
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract Asparagine, an important amino acid in mammals, is produced in several organs and is widely used for the production of other nutrients such as glucose, proteins, lipids, and nucleotides. Asparagine has also been reported to play a vital role
Externí odkaz:
https://doaj.org/article/1522c69b1ea14b5a88ec982d92c8e3e6
Autor:
Yuxin Liang, Deyuan Zhong, Zilong Zhang, Yuhao Su, Su Yan, Chunyou Lai, Yutong Yao, Ying Shi, Xiaolun Huang, Jin Shang
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract Background For chronic hepatitis B virus (HBV) infection patients, increasing evidence has demonstrated the effectiveness of expanding the indications and applicable population for antiviral therapy. However, the expanded indication of antiv
Externí odkaz:
https://doaj.org/article/3b7474b594724e7da090317db78b1c36
Single‐cell profiling reveals the metastasis‐associated immune signature of hepatocellular carcinoma
Autor:
Deyuan Zhong, Ying Shi, Wenzhe Ma, Yuxin Liang, Hanjie Liu, Yingying Qin, Lu Zhang, Qinyan Yang, Xiaolun Huang, Yuanjun Lu, Jin Shang
Publikováno v:
Immunity, Inflammation and Disease, Vol 12, Iss 5, Pp n/a-n/a (2024)
Abstract Aim Metastasis is the leading cause of mortality in hepatocellular carcinoma (HCC). The metastasis‐associated immune signature in HCC is worth exploring. Methods Bioinformatic analysis was conducted based on the single‐cell transcriptome
Externí odkaz:
https://doaj.org/article/74fb52403d144e5eb211aa1a49fd591c
Publikováno v:
PhotoniX, Vol 4, Iss 1, Pp 1-16 (2023)
Abstract There has been a rapidly growing demand for low-cost, integrated single-shot spectrometers to be embedded in portable intelligent devices. Even though significant progress has been made in this area, two major problems are still remaining, n
Externí odkaz:
https://doaj.org/article/ceab757d49044c9191843ff1a9d89fc3
Autor:
Wei Zhou, Wenxi Wang, Yuxin Liang, Ruibin Jiang, Fensheng Qiu, Xiying Shao, Yang Liu, Le Fang, Maowei Ni, Chenhuan Yu, Yue Zhao, Weijia Huang, Jiong Li, Michael J. Donovan, Lina Wang, Juan Ni, Dachi Wang, Ting Fu, Jianguo Feng, Xiaojia Wang, Weihong Tan, Xiaohong Fang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Kinase inhibitors against Cyclin Dependent Kinase 4 and 6 (CDK4/6i) are promising cancer therapeutic drugs. However, their effects are limited by primary or acquired resistance in virtually all tumor types. Here, we demonstrate that Leucine
Externí odkaz:
https://doaj.org/article/ebd32f1f746f477cb690bf30ad467f9b
Publikováno v:
Land, Vol 13, Iss 6, p 766 (2024)
Inhalable particulate matter (PM10) is a major air pollutant that has significant impacts on environmental climate and human health. Land-cover change is also a key factor influencing changes in atmospheric pollution. Changes in land-cover types can
Externí odkaz:
https://doaj.org/article/619577eb047e4ae293db454abf3097b1
Autor:
Riccardo Guidi, Christopher Wedeles, Daqi Xu, Krzysztof Kolmus, Sarah E. Headland, Grace Teng, Joseph Guillory, Yi Jimmy Zeng, Tommy K. Cheung, Subhra Chaudhuri, Zora Modrusan, Yuxin Liang, Stuart Horswell, Benjamin Haley, Sascha Rutz, Christopher Rose, Yvonne Franke, Donald S. Kirkpatrick, Jason A. Hackney, Mark S. Wilson
Publikováno v:
Cell Reports, Vol 42, Iss 12, Pp 113515- (2023)
Summary: Argonaute (AGO) proteins execute microRNA (miRNA)-mediated gene silencing. However, it is unclear whether all 4 mammalian AGO proteins (AGO1, AGO2, AGO3, and AGO4) are required for miRNA activity. We generate Ago1, Ago3, and Ago4-deficient m
Externí odkaz:
https://doaj.org/article/25462c6054024fa48c41ad2cf5a0b832