Výsledky vyhledávání - "Yuxiao Barnes"

Low levels of ABCG2 expression in adult AML blast samples

Autor: Anne Marie Colapietro, Brian P. Sorrentino, Brian L. Abbott, Michael Andreeff, Frank C. Marini, Yuxiao Barnes

Publikováno v: Blood. 100:4594-4601

Previous reports have suggested that the adenosine triphosphate–binding cassette protein ABCG2 (breast cancer resistance protein [BCRP], mitoxantrone resistance [MXR]) is associated with drug resistance in acute myeloid leukemia (AML). The aims of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67fdd1cff6ad64f7255079d30d079091
https://doi.org/10.1182/blood-2002-01-0271

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Bcrp1 gene expression is required for normal numbers of side population stem cells in mice, and confers relative protection to mitoxantrone in hematopoietic cells in vivo

Autor: Brian P. Sorrentino, Yuxiao Barnes, Lu-Bin Lan, John J. Morris, Sheng Zhou, John D. Schuetz

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America. 99(19)

Hematopoietic stem cells (HSCs) can be identified by a “side population” (SP) phenotype. Previous studies have implicated the ATP binding cassette transporter genesMdr1a/1band/orBcrp1in the SP phenotype. To define the relative role of these trans

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a0175e31d81ae9cfd45773e4efaf02e
https://pubmed.ncbi.nlm.nih.gov/12218177

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