Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Yuxiang, Fei"'
Autor:
Yuxiang Fei, Xiaojing Li, Zhongyang Lv, Zizheng Liu, Ya Xie, Jiaqi Chen, Weitong Li, Xiyu Liu, Hu Guo, Huan Liu, Zhaofeng Zhang, Xunhao Wang, Jingjing Fan, Chunqing Hu, Xiaoyu Jin, Ruiyang Jiang, Nuo Xu, Jiang Xia, Yang Li, Dongquan Shi
Publikováno v:
Bioactive Materials, Vol 40, Iss , Pp 624-633 (2024)
Osteoarthritis (OA) is a highly incident total joint degenerative disease with cartilage degeneration as the primary pathogenesis. The cartilage matrix is mainly composed of collagen, a matrix protein with a hallmark triple-helix structure, which unf
Externí odkaz:
https://doaj.org/article/506e57a6e7ca42e9907f89da7e69bbde
Autor:
Wei Sun, Zhongyang Lv, Weitong Li, Jun Lu, Ya Xie, Peng Wang, Ruiyang Jiang, Jian Dong, Hu Guo, Zizheng Liu, Yuxiang Fei, Guihua Tan, Maochun Wang, Kewei Ren, Jun Xu, Huiqing Sun, Xuefeng Jiang, Dongquan Shi
Publikováno v:
Journal of Orthopaedic Translation, Vol 44, Iss , Pp 114-124 (2024)
Background: Osteoarthritis (OA) is the most common age-related musculoskeletal disease. However, there is still a lack of therapy that can modify OA progression due to the complex pathogenic mechanisms. The aim of the study was to explore the role an
Externí odkaz:
https://doaj.org/article/b7256ec3c84148e99c525a46941f2edf
Autor:
Weitong Li, Zhongyang Lv, Peng Wang, Ya Xie, Wei Sun, Hu Guo, Xiaoyu Jin, Yuan Liu, Ruiyang Jiang, Yuxiang Fei, Guihua Tan, Huiming Jiang, Xucai Wang, Zizheng Liu, Zheng Wang, Nuo Xu, Wenli Gong, Rui Wu, Dongquan Shi
Publikováno v:
Advanced Science, Vol 11, Iss 16, Pp n/a-n/a (2024)
Abstract Osteoarthritis (OA) is the most common degenerative joint disease worldwide, with the main pathological manifestation of articular cartilage degeneration. It have been investigated that pharmacological activation of transient receptor potent
Externí odkaz:
https://doaj.org/article/60da3472d9c941309e776342bbf6c178
Autor:
Zhongyang Lv, Peng Wang, Weitong Li, Ya Xie, Wei Sun, Xiaoyu Jin, Ruiyang Jiang, Yuxiang Fei, Yuan Liu, Tianshu Shi, Hu Guo, Ziying Sun, Jintao Lin, Xucai Wang, Guihua Tan, Yizhang Wu, Nirong Bao, Dongquan Shi
Publikováno v:
Research, Vol 7 (2024)
Transient receptor potential vanilloid family member 1 (TRPV1) has been revealed as a therapeutic target of osteoarthritis (OA), the most common deteriorating whole joint disease, by impeding macrophagic inflammation and chondrocytes ferroptosis. How
Externí odkaz:
https://doaj.org/article/7a31ffa0faad49518eac3b94302526f7
Publikováno v:
BMC Neurology, Vol 22, Iss 1, Pp 1-6 (2022)
Abstract Background Even undergoing mechanical thrombectomy (MT), patients with acute vertebrobasilar artery occlusion (AVBAO) still have a high rate of mortality. Tirofiban is a novel antiplatelet agent which is now widely empirically used in acute
Externí odkaz:
https://doaj.org/article/1f6a631da66447799a6d3b0e29d2c6c8
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Cancer immunotherapy has opened a new landscape in cancer treatment, however, the poor specificity and resistance of most targeted therapeutics have limited their therapeutic efficacy. In recent years, the role of CAFs in immune regulation has been i
Externí odkaz:
https://doaj.org/article/f06842b067764652ba414d92866cc5d2
Autor:
Zhongyang Lv, Jie Han, Jiawei Li, Hu Guo, Yuxiang Fei, Ziying Sun, Jian Dong, Maochun Wang, Chunmei Fan, Weitong Li, Ya Xie, Wei Sun, Jiaqi Chen, Yuan Liu, Fufei Chen, Zizheng Liu, Anlong Liu, Rui Wu, Xingquan Xu, Wenjin Yan, Qing Jiang, Shiro Ikegawa, Xiao Chen, Dongquan Shi
Publikováno v:
EBioMedicine, Vol 84, Iss , Pp 104258- (2022)
Summary: Background: Osteoarthritis (OA) is the most common degenerative joint disease primarily characterized by cartilage destruction. The aim of this study was to investigate the role, molecular characteristics and potential therapeutic target of
Externí odkaz:
https://doaj.org/article/2ad496d0d4794e47b4c2c7faafebc493
Publikováno v:
BMC Neurology, Vol 22, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/9c68c060f356461ab4b5052a0bfece63
Autor:
Heng Sun, Ziying Sun, Xingquan Xu, Zhongyang Lv, Jiawei Li, Rui Wu, Yuxiang Fei, Guihua Tan, Zizheng Liu, Yuan Liu, Dongquan Shi
Publikováno v:
Antioxidants, Vol 11, Iss 12, p 2315 (2022)
Osteoarthritis (OA) is a low-level inflammatory disease in which synovial macrophage M1 polarization exacerbates the progression of synovitis and OA. Notedly, the ROS (reactive oxygen species) level in macrophages is intimately implicated in macropha
Externí odkaz:
https://doaj.org/article/b01c423058e549198aa4387dace408da
Autor:
Zhongyang Lv, Yannick Xiaofan Yang, Jiawei Li, Yuxiang Fei, Hu Guo, Ziying Sun, Jun Lu, Xingquan Xu, Qing Jiang, Shiro Ikegawa, Dongquan Shi
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Knee osteoarthritis (KOA) is the most common form of joint degeneration with increasing prevalence and incidence in recent decades. KOA is a molecular disorder characterized by the interplay of numerous molecules, a considerable number of which can b
Externí odkaz:
https://doaj.org/article/194b0df7cfc74343a0b30946802972d3