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Integrated Screening of Effective Anti-Insomnia Fractions of Zhi-Zi-Hou-Po Decoction via Drosophila melanogaster and Network Pharmacology Analysis of the Underlying Pharmacodynamic Material and Mechanism

Autor: Yijia Cao, Tiange Yang, Yu Sun, Chenning Zhang, Yuxia Qu, Yikun Sun, Shiting Ni, Tianyi Li, Hao Wu, Renyun Zhao, Runhua Liu

Publikováno v: ACS Omega, Vol 6, Iss 13, Pp 9176-9187 (2021)

Insomnia is an anabatic epidemiology, while the mechanism is extremely complicated; it remains one of the major scientific challenges in life sciences. Because of the advantage of having a similar genetic background and circadian rhythm as those of h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d648d43aeeef00e9a0f26d77d793ebb
https://doi.org/10.1021/acsomega.1c00445

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Integrating UPLC-QE-Orbitrap-MS technology and network pharmacological method to reveal the mechanism of Bailemian capsule to relieve insomnia

Autor: Hao Wu, Jiaqi Wang, Tianyi Li, Yuxia Qu, Yijia Cao, Yuwei Yang, Yikun Sun, Chenning Zhang

Publikováno v: Natural Product Research. 36:2554-2558

Bailemian capsule (BLMC) is a Chinese patent drug for treating insomnia with excellent curative effects. But there are few researches on it. In this research, a rapid separation and identification method using UPLC-QE-Orbitrap-MS was established, and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21fd5a652b4edaaf06414b728cea337a
https://doi.org/10.1080/14786419.2021.1900176

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LC–MS-Based Qualitative Analysis and Pharmacokinetic Integration Network Pharmacology Strategy Reveals the Mechanism of Phlomis brevidentata H.W.Li Treatment of Pneumonia

Autor: Yikun Sun, Tsring Nyima, Yu Sun, Yuxia Qu, Chuanxin Liu, Runhua Liu, Shuofeng Zhang, Yijia Cao, Chenning Zhang

Publikováno v: ACS Omega, Vol 6, Iss 6, Pp 4495-4505 (2021)
ACS Omega

Phlomis brevidentata H.W.Li Radix (PbR) is a rare traditional Tibetan medicine, and it is widely used in the Chinese Tibetan region for the treatment of pharyngitis, pneumonia, and so forth. Nevertheless, there is very little research on its modern p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d510ce192451df9eade23d58fcbba930
https://doi.org/10.1021/acsomega.0c06201

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Rapid characterization the chemical constituents of Bergenia purpurascens and explore potential mechanism in treating osteoarthritis by ultra high performance liquid chromatography coupled with quadrupole time‐of‐flight mass spectrometry combined with network pharmacology

Autor: Na Zhang, Yikun Sun, Yuxia Qu, Ciren Nima, Yu Sun, Chenning Zhang, Runhua Liu, Hao Wu, Shuofeng Zhang, Quzeng Danpei

Publikováno v: Journal of Separation Science. 43:3333-3348

In recent years, direct and indirect evidence has been found of the efficacy of the traditional Chinese medicine Bergenia purpurascens in treating arthritis and osteoarthritis. Several major components, such as bergenin and 11-O-galloylbergenin, have

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a58895e52fa0927d7590e7c6a820d4c1
https://doi.org/10.1002/jssc.201901284

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Bidirectional regulation of i-type lysozyme on cutaneous wound healing

Autor: Yuwei Yang, Yuxia Qu, Tianyi Li, Di Geng, Yikun Sun, Chenning Zhang, Yijia Cao, Tiange Yang

Publikováno v: Biomedicine & Pharmacotherapy, Vol 131, Iss, Pp 110700-(2020)

Objective This study aimed to assess the effect and mechanism of i-type lysozyme on cutaneous wound healing animal model and Multiple cell models both in vivo and in vitro. Methods Therefore, to evaluate its regenerative efficacy on wound healing pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60ed2ae92ef775e48ab5dae5e1fa9293
http://www.sciencedirect.com/science/article/pii/S0753332220308933

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Rapid characterization the chemical constituents of Bergenia purpurascens and explore potential mechanism in treating osteoarthritis by ultra high performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry combined with network pharmacology

Autor: Yuxia, Qu, Chenning, Zhang, Runhua, Liu, Hao, Wu, Yu, Sun, Na, Zhang, Ciren, Nima, Quzeng, Danpei, Shuofeng, Zhang, Yikun, Sun

Publikováno v: Journal of separation scienceREFERENCES. 43(16)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8abf6a549fbb935ed465fc92bd1b6843
https://pubmed.ncbi.nlm.nih.gov/32496008

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