Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Yuwen, Ke"'
Publikováno v:
Cell Reports, Vol 42, Iss 3, Pp 112210- (2023)
Summary: Cis-regulatory elements regulate gene expression and lineage specification. However, the potential regulation of cis-elements on mammalian embryogenesis remains largely unexplored. To address this question, we perform single-cell assay for t
Externí odkaz:
https://doaj.org/article/67836124731a48d792ef7723452af29c
Autor:
Jingwen Zhang, Wenzhe Xia, Jiaqi Zhou, Shaogang Qin, Lin Lin, Ting Zhao, Huarong Wang, Chen Mi, Yifan Hu, Zixuan Chen, Tianhua Zhu, Xinyu Yang, Tuo Zhang, Guoliang Xia, Yuwen Ke, Chao Wang
Publikováno v:
International Journal of Biological Sciences; 2024, Vol. 21 Issue 10, p3863-3880, 18p
Autor:
Hao Yu, Na Ai, Ping Peng, Yuwen Ke, Xuepeng Chen, Yun Li, Ting Zhao, Shan Jiang, Jiang Liu, Lan Jiang
The regulatory programs driving early organogenesis in human is complex and still poorly understood. We performed parallel profiling of gene expression and chromatin accessibility to 28 human fetal tissue samples representing 14 organs in the first t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0c4b799fb525a394e6dcaaf5317840a
https://doi.org/10.1101/2021.11.02.466852
https://doi.org/10.1101/2021.11.02.466852
Publikováno v:
SCIENTIA SINICA Vitae. 51:556-566
In the early development of animals, both the organism morphology and the genes expression undergo dramatic changes, and epigenetic information plays an important role in this process. In recent years, benefit from the development of genome and other
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd86965d7c2b5593672902fa1356ea5f
https://doi.org/10.1360/ssv-2019-0229
https://doi.org/10.1360/ssv-2019-0229
Autor:
Hui Liu, Wenrong Tao, Zhenzhen Hou, Yaoyu Sun, Zi-Jiang Chen, Keliang Wu, Zhenbo Liu, Han Zhao, Jingye Zhang, Yuwen Ke, Xuepeng Chen, Lei Gao, Jiang Liu
Publikováno v:
Nature. 576:306-310
In the interphase of the cell cycle, chromatin is arranged in a hierarchical structure within the nucleus1,2, which has an important role in regulating gene expression3-6. However, the dynamics of 3D chromatin structure during human embryogenesis rem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab4574e291f622e3bdcde6c8c8198a1c
https://doi.org/10.1038/s41586-019-1812-0
https://doi.org/10.1038/s41586-019-1812-0
Autor:
Xuepeng, Chen, Yuwen, Ke, Keliang, Wu, Han, Zhao, Yaoyu, Sun, Lei, Gao, Zhenbo, Liu, Jingye, Zhang, Wenrong, Tao, Zhenzhen, Hou, Hui, Liu, Jiang, Liu, Zi-Jiang, Chen
Publikováno v:
Nature. 576(7786)
In the interphase of the cell cycle, chromatin is arranged in a hierarchical structure within the nucleus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::00925ca646c6f9e77c0096563fee63c8
https://pubmed.ncbi.nlm.nih.gov/31801998
https://pubmed.ncbi.nlm.nih.gov/31801998
Autor:
Guoqiang Li, Likun Gong, Jiang Liu, Fulin Lian, Tong Zheng, Baoen Chen, Luming Zhou, Cai-Guang Yang, Naixia Zhang, Shouzhe Gong, Zhongqiang Guo, Li Li, Ke Chen, Yi Wen, Hualiang Jiang, Jiafei Li, Yong Yang, Yuwen Ke, Liqun Zhou, Sisheng Ouyang, Dafang Zhong, Zhiwei Gao, Ran Zhou, Jing Lu, Yue Huang, Xiao-Bo Qiu, Shang-Dong Yang, Jingqiu Liu, Cheng Luo, Hong Ding, Bidong Zhang, Liu-Liang Mao, Jin Ren
Publikováno v:
Cancer Cell. 30:474-484
In the cytoplasm of virtually all clear-cell renal cell carcinoma (ccRCC), speckle-type POZ protein (SPOP) is overexpressed and misallocated, which may induce proliferation and promote kidney tumorigenesis. In normal cells, however, SPOP is located i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a98e8e2d401da735f4fa1fc0eecc966
https://doi.org/10.1016/j.ccell.2016.08.003
https://doi.org/10.1016/j.ccell.2016.08.003
Autor:
Xiangjin Kang, Ping Liu, Jie Yan, Rong Li, Guoqiang Li, Congru Li, Xiaocui Xu, Jialei Duan, Yue Zhao, Jiang Liu, Hongcui Zhao, Xin Ma, Ying Lian, Yaoyong Chen, Yong Fan, Yang Yu, Xuepeng Chen, Yuwen Ke
Publikováno v:
Cell Discovery, Vol 4, Iss 1, Pp 1-12 (2018)
Cell Discovery
Cell Discovery
DNA methylation plays important roles during development. However, the DNA methylation reprogramming of functional elements has not been fully investigated during mammalian embryonic development. Herein, using our modified MethylC-Seq library generat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca2853f30f1e0b43c8174c0bde0a0650
https://doi.org/10.1038/s41421-018-0039-9
https://doi.org/10.1038/s41421-018-0039-9
Autor:
Chuan He, Zhengzheng Xu, Zhongwu Li, Zhongqiang Guo, Zhiying Xu, Bi-Feng Yuan, Xiongjun Ye, Liqun Zhou, Yuwen Ke, Qin Ma, Ke Chen, Weimin Ci, Yuanyuan Zhou, Yiqiang Liu, Xuesong Li, Jing Zhang, Jiang Liu
Publikováno v:
Cell Research. 26:103-118
Both 5-methylcytosine (5mC) and its oxidized form 5-hydroxymethylcytosine (5hmC) have been proposed to be involved in tumorigenesis. Because the readout of the broadly used 5mC mapping method, bisulfite sequencing (BS-seq), is the sum of 5mC and 5hmC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5c7761bee23dc2bed2f76ba9f6c9341
https://doi.org/10.1038/cr.2015.150
https://doi.org/10.1038/cr.2015.150
Autor:
Xiangjin Kang, Jiang Liu, Guoqiang Li, Ping Liu, Yuwen Ke, Rong Li, Yong Fan, Xiaofang Sun, Xiaocui Xu, Ying Lian, Jie Yan, Jie Qiao, Yaoyong Chen, Jialei Duan, Yang Yu, Xin Ma, Hongcui Zhao, Xuepeng Chen, Yue Zhao, Congru Li, Jianqiao Liu
Publikováno v:
Journal of genetics and genomics = Yi chuan xue bao. 44(10)
Proper reprogramming of parental DNA methylomes is essential for mammalian embryonic development. However, it is unknown whether abnormal methylome reprogramming occurs and is associated with the failure of embryonic development. Here we analyzed the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3f5dc4de3084dd604db9bc1a81b7f5f
https://pubmed.ncbi.nlm.nih.gov/29037989
https://pubmed.ncbi.nlm.nih.gov/29037989