Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Yuwei Cong"'
Autor:
Zhongxiao Li, Yuwei Cong, Xin Chen, Jiping Qi, Jingxian Sun, Tao Yan, He Yang, Junsi Liu, Enzhou Lu, Lixiang Wang, Jiafeng Li, Hong Hu, Cheng Zhang, Quan Yang, Jiawei Yao, Penglei Yao, Qiuyi Jiang, Wenwu Liu, Jiangning Song, Lawrence Carin, Yupeng Chen, Shiguang Zhao, Xin Gao
Publikováno v:
iScience, Vol 26, Iss 1, Pp 105872- (2023)
Summary: Diagnosis of primary brain tumors relies heavily on histopathology. Although various computational pathology methods have been developed for automated diagnosis of primary brain tumors, they usually require neuropathologists’ annotation of
Externí odkaz:
https://doaj.org/article/b29bcda62de84d608bd7c769491d33c9
Publikováno v:
Remote Sensing, Vol 15, Iss 17, p 4217 (2023)
With the comprehensive promotion of digital construction in China, cameras scattered throughout the country are of great significance in obtaining first-hand data. However, their potential role is limited due to the lack of georeference information o
Externí odkaz:
https://doaj.org/article/276f24d95e514a3ab8570b08a646fedc
Publikováno v:
Journal of materials chemistry. B. 3(24)
Combination therapy based on polymer–drug conjugates is one of the exciting developments in polymeric drug delivery systems. A single polymer carrier with two or more drugs attached is advantageous because it provides a platform for synergistic age
Autor:
Yubin Huang, Zhigang Xie, Dongfang Zhou, Xiabin Jing, Yuwei Cong, Shasha He, Zigui Wang, Jizhen Li, Xuesi Chen
Publikováno v:
RSC Advances. 6:20366-20373
Platinum(II) complexes are used for treating over half of cancers in the clinic. However, their application is accompanied with acquired resistance and severe toxic side effects. To address these challenges, a multifunctional single drug constructed
Analysis of germline mutations in Chinese colorectal cancer patients with next-generation sequencing
Publikováno v:
Web of Science
e13651 Background: Colorectal cancer (CRC) remains one of the leading causes of morbidity and mortality around the world. Familial cancer syndromes are common in CRC, inherited syndromes including Lynch syndrome (LS), familial adenomatous polyposis (
Autor:
Jianxun Ding, Xing-Jie Liang, Yubin Huang, Zigui Wang, Haihua Xiao, Hejian Xiong, Xuesi Chen, Dongfang Zhou, Yuwei Cong, Chan Li
Publikováno v:
Advanced materials (Deerfield Beach, Fla.). 30(11)
Most of the current nanoparticle-based therapeutics worldwide failing in clinical trials face three major challenges: (i) lack of an optimum drug delivery platform with precise composition, (ii) lack of a method of directly monitoring the fate of a s
Autor:
Xiabin Jing, Yubin Huang, Jizhen Li, Shasha He, Zhigang Xie, Xuesi Chen, Dongfang Zhou, Yuwei Cong
Publikováno v:
Journal of Materials Chemistry B. 3:8203-8211
Reduction-responsive nano-carriers have been confirmed to be promising for intracellular drug delivery. To develop multifunctional polymer-based drug delivery system, a novel dextran-Pt(iv) conjugate was synthesized by conjugating Pt(iv) to the side
Autor:
Yanxin Qi, Yuwei Cong, Xuesi Chen, Hejian Xiong, Dongfang Zhou, Shasha He, Yanjuan Wu, Xiabin Jing, Zhigang Xie, Yubin Huang
Publikováno v:
Biomaterials Science. 3:182-191
The main obstacles to cancer therapy are the inability to target cancer cells and the acquired drug resistance after a period of chemotherapy. Reduced drug uptake and DNA repair are the two main mechanisms involved in cisplatin resistance. In the pre
Publikováno v:
ACS medicinal chemistry letters. 7(10)
Self-repair of nuclear DNA damage is the most known reason that leads to drug resistance of cancer tissue and limited therapeutic efficacy of anticancer drugs. Inhibition of protein phosphatase 2A (PP2A) would block DNA damage-induced defense of canc
Autor:
Xiang Ban, Yunhe Gu, Tao Liu, Jiping Qi, Qi Huang, Ruibo Zhao, Yuwei Cong, He Wu, Dandan Wang
Publikováno v:
Journal of the Neurological Sciences. 270:172-183
Brain edema is one of the most frequent and serious complications of intracerebral hemorrhage (ICH), but how the ICH cause brain edema is unknown. Our studies were designed to investigate the regulation and distribution of protease nexin-1 (PN-1), th