Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Yuwaraj, Kadariya"'
Autor:
Ralph A. Pietrofesa, Shampa Chatterjee, Yuwaraj Kadariya, Joseph R. Testa, Steven M. Albelda, Melpo Christofidou-Solomidou
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 17, p 10085 (2022)
Although alveolar macrophages play a critical role in malignant transformation of mesothelial cells following asbestos exposure, inflammatory and oxidative processes continue to occur in the mesothelial cells lining the pleura that may contribute to
Externí odkaz:
https://doaj.org/article/4f773da28553445c99bf56a6aab37cf7
Autor:
Yuwaraj Kadariya, Eleonora Sementino, Ujjawal Shrestha, Greg Gorman, Jonathan M White, Eric A Ross, Margie L Clapper, Nouri Neamati, Mark Steven Miller, Joseph R Testa
Publikováno v:
Carcinogenesis. 43:1137-1148
Malignant mesothelioma (MM) is an incurable cancer of the serosal lining that is often caused by exposure to asbestos. Therefore, novel agents for the prevention and treatment of this disease are urgently needed. Asbestos induces the release of pro-i
Autor:
Joseph R. Testa, Arti Shukla, Brooke T. Mossman, Mitchell Cheung, Melpo Christofidou-Solomidou, Ralph A. Pietrofesa, Andres J. Klein-Szanto, Kathy Q. Cai, Jacqueline Talarchek, Craig W. Menges, Yuwaraj Kadariya
Conflict of Interest Form from Inflammation-Related IL1β/IL1R Signaling Promotes the Development of Asbestos-Induced Malignant Mesothelioma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d3f636251d4c0eafdf96045430ea928
https://doi.org/10.1158/1940-6207.22534228
https://doi.org/10.1158/1940-6207.22534228
Autor:
Joseph R. Testa, Arti Shukla, Brooke T. Mossman, Mitchell Cheung, Melpo Christofidou-Solomidou, Ralph A. Pietrofesa, Andres J. Klein-Szanto, Kathy Q. Cai, Jacqueline Talarchek, Craig W. Menges, Yuwaraj Kadariya
Top, Scatter plot showing difference in MM incidence between asbestos-exposed wild-type (WT, Asc +/+), Asc+/-, and Asc-/- mice. Bottom, summary showing statistically significant difference in MM incidence between WT mice and Asc-/- mice (p < 0.05), b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f2064f24d155b6b796c032b99704cf9
https://doi.org/10.1158/1940-6207.22534222
https://doi.org/10.1158/1940-6207.22534222
Autor:
Joseph R. Testa, Jonathan Chernoff, James S. Duncan, Suraj Peri, Kathy Q. Cai, Sofiia Karchugina, Ujjawal Shrestha, Anna-Mariya Kukuyan, Yinfei Tan, Craig W. Menges, Mitchell Cheung, Yuwaraj Kadariya, Eleonora Sementino
Supplementary Data from Inactivation of p21-Activated Kinase 2 (Pak2) Inhibits the Development of Nf2-Deficient Tumors by Restricting Downstream Hedgehog and Wnt Signaling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04688cac9745b552483384c204e965d3
https://doi.org/10.1158/1541-7786.22527542.v1
https://doi.org/10.1158/1541-7786.22527542.v1
Autor:
Joseph R. Testa, Arti Shukla, Brooke T. Mossman, Mitchell Cheung, Melpo Christofidou-Solomidou, Ralph A. Pietrofesa, Andres J. Klein-Szanto, Kathy Q. Cai, Jacqueline Talarchek, Craig W. Menges, Yuwaraj Kadariya
Exposure to asbestos is causally associated with the development of malignant mesothelioma, a cancer of cells lining the internal body cavities. Malignant mesothelioma is an aggressive cancer resistant to all current therapies. Once inhaled or ingest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4cb1ba65900258934f30ef98ead6d41
https://doi.org/10.1158/1940-6207.c.6547414.v1
https://doi.org/10.1158/1940-6207.c.6547414.v1
Autor:
Joseph R. Testa, Frank J. Rauscher, Andres J. Klein-Szanto, Suraj Peri, Michael J. Slifker, Kathy Q. Cai, Yinfei Tan, Mitchell Cheung, Craig W. Menges, Yuwaraj Kadariya, Eleonora Sementino, Anna-Mariya Kukuyan
Analysis of The Cancer Genome Atlas (TCGA) mesothelioma cases.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::929da7fee491780d867e1f790e2f3f4a
https://doi.org/10.1158/0008-5472.22420947
https://doi.org/10.1158/0008-5472.22420947
Autor:
Joseph R. Testa, Frank J. Rauscher, Andres J. Klein-Szanto, Suraj Peri, Michael J. Slifker, Kathy Q. Cai, Yinfei Tan, Mitchell Cheung, Craig W. Menges, Yuwaraj Kadariya, Eleonora Sementino, Anna-Mariya Kukuyan
Assay IDs for quantitative RT-PCR analysis to validate genes differentially expressed between malignant mesotheliomas (MMs) derived from triple-CKO mice versus those from double-CKO mice.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::970d9decee3a9317212e5ec30f8058d9
https://doi.org/10.1158/0008-5472.22420944.v1
https://doi.org/10.1158/0008-5472.22420944.v1
Autor:
Joseph R. Testa, Frank J. Rauscher, Andres J. Klein-Szanto, Suraj Peri, Michael J. Slifker, Kathy Q. Cai, Yinfei Tan, Mitchell Cheung, Craig W. Menges, Yuwaraj Kadariya, Eleonora Sementino, Anna-Mariya Kukuyan
Characterization of malignant mesothelioma (MM) from Bap1f/f mouse, which was detected 45 weeks after intrathoracic injection of Adeno-Cre virus. A, Immunoblot confirming loss of Bap1 expression in MM from Bap1 conditional knockout mouse 526, with tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::149c16ee0de35107e953c3e20081b198
https://doi.org/10.1158/0008-5472.22420956.v1
https://doi.org/10.1158/0008-5472.22420956.v1
Autor:
Joseph R. Testa, Frank J. Rauscher, Andres J. Klein-Szanto, Suraj Peri, Michael J. Slifker, Kathy Q. Cai, Yinfei Tan, Mitchell Cheung, Craig W. Menges, Yuwaraj Kadariya, Eleonora Sementino, Anna-Mariya Kukuyan
100 of the top gene sets differentially affected (FDR < 0.25) in MMs from triple-CKOa versus those from double-CKO mice by using GSEA applied to MSigDB gene sets.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b3fca8f1499ac364e0f5ae24d7f6446
https://doi.org/10.1158/0008-5472.22420938.v1
https://doi.org/10.1158/0008-5472.22420938.v1