Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Yuvraj Nikam"'
Autor:
Aarti A. Jagtap, Sanket M. Shah, Frank Steiniger, Dinesh T. Makhija, Mukul Ashtikar, Ankitkumar S. Jain, Mangal S. Nagarsenker, Yuvraj Nikam, Rajiv P. Gude, Alfred Fahr
Publikováno v:
International Journal of Pharmaceutics. 490:391-403
The present study compares three vesicular systems, cationic LeciPlex, invasomes, and conventional liposomes for their ability to deliver drugs deep into the skin. Skin penetration ability of the three vesicular systems was studied for two drugs name
Autor:
Amrita N. Bajaj, Peeyush N. Goel, Yuvraj Nikam, S. M. Patil, Shruti Shrikhande, Rajani B. Athawale, Darshana S. Jain, Preeti Raut, Rajiv P. Gude
Publikováno v:
Drug Delivery. 23:989-1006
Hydrophobicity of PLA nanoparticles makes them a good substrate for macrophageal and reticulo-endothelial system uptake. Long-circulating properties can be imparted to these particles by coating them with hydrophilic stabilizers. Surface-modified PLA
Autor:
Peeyush N. Goel, Mangal S. Nagarsenker, Ankitkumar S. Jain, Yuvraj Nikam, Sanket M. Shah, Vivek Dhawan, Rajiv P. Gude
Publikováno v:
Biomedicine & Pharmacotherapy. 68:429-438
Tamoxifen (TMX), an estrogen receptor (ER) antagonist, incorporated at surface of liposomes loaded with Doxorubicin (DOX), was hypothesized to serve as ligand for targeting overexpressed ERs on surface and cytosol of breast cancer cells, in addition
Poly lactic acid (PLA) nanoparticles sustain the cytotoxic action of temozolomide in C6 Glioma cells
Autor:
Rajani B. Athawale, Amrita N. Bajaj, Darshana S. Jain, Peeyush N. Goel, Rajiv P. Gude, Yuvraj Nikam, Shruti Shrikhande
Publikováno v:
Biomedicine & Aging Pathology. 3:201-208
Targeting brain tumor largely depends on the chemotherapeutic agent uptake by the cancerous cells. The uptake further depends on its dosage form, route of administration and surface modifications. In the present study, temozolomide (TMZ) loaded into
Autor:
Ankitkumar S. Jain, Frank Steiniger, Jana Thamm, Mangal S. Nagarsenker, Rajiv P. Gude, Sanket M. Shah, Alfred Fahr, Yuvraj Nikam
Publikováno v:
Journal of Biomedical Nanotechnology. 9:1230-1240
Novel lipid nanocarriers, GeluPearl (GP) comprising of Precirol ATO 5 lipid nanoparticles with (GPNLC) or without oil (GPSLN), loaded with Quercetin (QR), were successfully fabricated to improve therapeutic efficacy. QR loaded GP nanoparticles were o
Autor:
Rajashri Balasaheb Sumbe, Chandrashekhar Laxman Bhingare, Rohini Yuvraj Nikam, Prasad V. Kadam, Manohar J. Patil
Publikováno v:
Journal of Biological and Scientific Opinion. 1:21-24
Standardization is used in herbal medicine to try to make extracts of the same herbs as similar to each other. It is used to describe all measures which are tak en during the manufacturing process and quality control leading to a reproducible quality
Publikováno v:
Pharmaceutical Methods. 4:43-45
Introduction: Turmeric (Curcuma Longa Linn.) belongs to Zingiberaceae family, in which major constituents are curcuminoids (approx. 6%) of which curcumin constituents 50e60%. The standard Curcumin and isolated Curcumin creams were prepared by o/w emu
Autor:
Rajiv P. Gude, Yuvraj Nikam, Sanket M. Shah, Dinesh T. Makhija, Ankitkumar S. Jain, Mangal S. Nagarsenker, Aarti G. Jagtap, Peeyush N. Goel
Publikováno v:
Pharmaceutical development and technology. 21(1)
The usefulness of Docetaxel (DT) as an anti-cancer agent is limited to parenteral route owing to its very poor oral bioavailability. Thus, to improve its oral efficacy, DT was loaded in novel cationic lipid nanocapsules (DT CLNC). The DT CLNC possess
Autor:
Vivek Dhawan, Rajiv P. Gude, Ganesh Joshi, Yuvraj Nikam, Mangal S. Nagarsenker, Ankitkumar S. Jain, Rita Mulherkar
Publikováno v:
Cellular oncology (Dordrecht). 37(5)
Cationic agents have been reported to possess anti-neoplastic properties against various cancer cell types. However, their complexes with lipids appear to interact differently with different cancer cells. The purpose of this study was to (i) design a
Autor:
Mukesh Ukawala, Kesarla Rajesh, Yuvraj Nikam, R.S.R. Murthy, Arehalli S. Manjappa, Rajiv P. Gude, Kinjal Makwana, Peeyush N. Goel, Makam P. Vekataraju
Publikováno v:
Pharmaceutical research. 30(10)
The presence of 7-epidocetaxel in docetaxel injection and in vivo epimerisation has been reported to be the cause for development of tumor resistance to chemotherapy including docetaxel by inducing tumor cell protein cytochrome P450 1B1. The objectiv