Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Yuval Mulla"'
Dynamic properties of allosteric complexes are crucial for cellular information processing. However, direct observations of allosteric switches have been limited to compact molecular assemblies. Here, we reportin vivoFRET measurements of spontaneous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::993d37a7dac9bffc729c17c22353e538
https://doi.org/10.1101/2022.12.04.518992
https://doi.org/10.1101/2022.12.04.518992
Publikováno v:
Phage (New Rochelle)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be46e5f5dcf20468292570856cf38558
https://doi.org/10.1089/phage.2021.29019.eve
https://doi.org/10.1089/phage.2021.29019.eve
Publikováno v:
Nature Reviews Physics. 1:249-263
The cells and tissues that make up our body manage contradictory mechanical demands. It is crucial for their survival to be able to withstand large mechanical loads, but it is equally crucial for them to produce forces and actively change shape durin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54066ef595c068c3cbd0b642e24c4d5d
https://doi.org/10.1038/s42254-019-0036-4
https://doi.org/10.1038/s42254-019-0036-4
Autor:
Yuval Mulla, Mario J Avellaneda, Antoine Roland, Lucia Baldauf, Wonyeong Jung, Taeyoon Kim, Sander J Tans, Gijsje H Koenderink
Molecular catch bonds are ubiquitous in biology and well-studied in the context of leukocyte extravasion1, cellular mechanosensing2,3, and urinary tract infection4. Unlike normal (slip) bonds, catch bonds strengthen under tension. The current paradig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da93613b9b4ef17fbaa4b1f629978869
https://doi.org/10.1101/2020.07.27.219618
https://doi.org/10.1101/2020.07.27.219618
Publikováno v:
Current Opinion in Systems Biology. 28:100365
Antibiotic resistance is a growing public health problem. To gain a fundamental understanding of resistance evolution, a combination of systematic experimental and theoretical approaches is required. Evolution experiments combined with next-generatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6b8f63eaac03a4ab145ce06ace84521
https://doi.org/10.1016/j.coisb.2021.100365
https://doi.org/10.1016/j.coisb.2021.100365
Publikováno v:
Physical Review Letters, 122(21):218102. American Physical Society
Mulla, Y, Mackintosh, F C & Koenderink, G H 2019, ' Origin of Slow Stress Relaxation in the Cytoskeleton ', Physical Review Letters, vol. 122, no. 21, 218102 . https://doi.org/10.1103/PhysRevLett.122.218102
Mulla, Y, Mackintosh, F C & Koenderink, G H 2019, ' Origin of Slow Stress Relaxation in the Cytoskeleton ', Physical Review Letters, vol. 122, no. 21, 218102 . https://doi.org/10.1103/PhysRevLett.122.218102
Dynamically crosslinked semiflexible biopolymers such as the actin cytoskeleton govern the mechanical behavior of living cells. Semiflexible biopolymers nonlinearly stiffen in response to mechanical loads, whereas the crosslinker dynamics allow for s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea94127a50dc2f1f21940d1dd2b827b4
https://hdl.handle.net/1871.1/6d10c898-6f91-44a3-937e-54a4da6e49a9
https://hdl.handle.net/1871.1/6d10c898-6f91-44a3-937e-54a4da6e49a9
Publikováno v:
Soft matter. 15(14)
Transiently crosslinked actin filament networks allow cells to combine elastic rigidity with the ability to deform viscoelastically. Theoretical models of semiflexible polymer networks predict that the crosslinker unbinding rate governs the timescale
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::049da515c4234465be402822b3964869
https://pubmed.ncbi.nlm.nih.gov/30900710
https://pubmed.ncbi.nlm.nih.gov/30900710
Autor:
Afshin Vahid, Pouyan E. Boukany, Aswin Muralidharan, Vaishnavi Kathavi, Lotte Stam, Lea Rems, Gijsje H. Koenderink, Michiel T. Kreutzer, Yuval Mulla, Dayinta L. Perrier
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports
Scientific Reports, 9(1)
Scientific Reports
Scientific Reports, 9(1)
We study the role of a biomimetic actin network during the application of electric pulses that induce electroporation or electropermeabilization, using giant unilamellar vesicles (GUVs) as a model system. The actin cortex, a subjacently attached inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f38b04a2a2a6965878a3c94fef381873
https://doi.org/10.1038/s41598-019-44613-5
https://doi.org/10.1038/s41598-019-44613-5
Publikováno v:
Physical Review Letters. 120
In viscoelastic materials, individually short-lived bonds collectively result in a mechanical resistance which is long-lived but finite, as ultimately cracks appear. Here we provide a microscopic mechanism by which cracks emerge from the nonlinear lo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3efdc7bbd3b62b0d5f4eff9c65bfc8d
https://doi.org/10.1103/physrevlett.120.268002
https://doi.org/10.1103/physrevlett.120.268002
Autor:
Yuval Mulla, Vaishnavi Kathavi, Gijsje H. Koenderink, Afshin Vahid, Aswin Muralidharan, Lotte Stam, Dayinta L. Perrier, Lea Rems, Pouyan E. Boukany, Michiel T. Kreutzer
We study the role of a biomimetic actin cortex during the application of electric pulses that induce electroporation or electropermeabilization, using giant unilamellar vesicles (GUVs) as a model system. The actin cortex, a subjacently attached inter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6068a0346b99dc85d669d4bd129e61b8
https://doi.org/10.1101/338566
https://doi.org/10.1101/338566