Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Yuval, Nov"'
Publikováno v:
Transactions of the Association for Computational Linguistics, Vol 11 (2023)
Externí odkaz:
https://doaj.org/article/feda351b415f432280ae2b036f13276a
Autor:
Daniel Melamed, Yuval Nov, Assaf Malik, Michael B. Yakass, Evgeni Bolotin, Revital Shemer, Edem K. Hiadzi, Karl L. Skorecki, Adi Livnat
Publikováno v:
Genome Research. 32:488-498
Although it is known that the mutation rate varies across the genome, previous estimates were based on averaging across various numbers of positions. Here, we describe a method to measure the origination rates of target mutations at target base posit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0886de8b2e778b3eabfb7a7b24b7029
https://doi.org/10.1101/gr.276103.121
https://doi.org/10.1101/gr.276103.121
Autor:
Yuval Nov
Publikováno v:
Biochemistry.
We present a novel statistical learning method for studying context-dependent error rates in error-prone polymerase chain reaction (PCR) experiments. We demonstrate the method by applying it to error-prone PCR sequencing data and show how it may be e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8580117dac2845f3961da25cabd6396e
https://pubmed.ncbi.nlm.nih.gov/36153985
https://pubmed.ncbi.nlm.nih.gov/36153985
Autor:
Daniel, Melamed, Yuval, Nov, Assaf, Malik, Michael B, Yakass, Evgeni, Bolotin, Revital, Shemer, Edem K, Hiadzi, Karl L, Skorecki, Adi, Livnat
Publikováno v:
Genome research. 32(3)
Although it is known that the mutation rate varies across the genome, previous estimates were based on averaging across various numbers of positions. Here, we describe a method to measure the origination rates of target mutations at target base posit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2db46cf82306f3cc0c3e8bb52dc2b0b6
https://pubmed.ncbi.nlm.nih.gov/35031571
https://pubmed.ncbi.nlm.nih.gov/35031571
Autor:
Riva Fineman, Dvora Sahar, Nivin Moustafa-Hawash, Shimrit Ringelstein-Harlev, Nuhad Haddad, Dana Yehudai-Ofir, Jacob M. Rowe, Yuval Nov, Ofrat Beyar-Katz, Noa Lavi, Yishai Ofran, Tsila Zuckerman, Israel Henig
Publikováno v:
Leukemia & Lymphoma. 60:2449-2456
Autologous stem cell transplantation (ASCT), intensifying anti-leukemic effects without significant treatment-related mortality (TRM), is particularly appealing in AML with favorable genetic/molecular profile. This study retrospectively evaluated the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c37d52a38b5d8ec750a0781443a23143
https://doi.org/10.1080/10428194.2019.1594214
https://doi.org/10.1080/10428194.2019.1594214
Autor:
Adi Livnat, Karl Skorecki, Daniel Melamed, Revital Shemer, Edem K. Hiadzi, Evgeni Bolotin, Yuval Nov, Michael Bright Yakass, Assaf Malik
While it is known that the mutation rate varies across the genome, previous estimates were based on averaging across various numbers of positions. Here we describe a method to measure the origination rates of target mutations at target base positions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c07176830337b3225db8f69ca4cca75f
https://doi.org/10.1101/2021.05.24.443729
https://doi.org/10.1101/2021.05.24.443729
Autor:
Yuval Nov
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68069 (2013)
Saturation mutagenesis is a widely used directed evolution technique, in which a large number of protein variants, each having random amino acids in certain predetermined positions, are screened in order to discover high-fitness variants among them.
Externí odkaz:
https://doaj.org/article/ee5415c3f6234980ad63df957e41f4fd
Autor:
Richard Lonsdale, Kirsty J. McLean, Charles G. Gamble, Yuval Nov, Christophe Farès, Aitao Li, Julia B. Lingnau, Adrian J. Mulholland, Manfred T. Reetz, David Leys, Heike Hinrichs, Alfred Deege, Sabrina Hoebenreich, Carlos G. Acevedo-Rocha, Nathalie Nett, Cornelia Wirtz, Andrew W. Munro
Publikováno v:
Acevedo-Rocha, C G, Gamble, C, Lonsdale, R, Li, A, Nett, N, Hoebenreich, S, Lingnau, J B, Wirtz, C, Fares, C, Hinrichs, H, Deege, A, Mulholland, A J, Nov, Y, Leys, D, Mclean, K, Munro, A & Reetz, M T 2018, ' P450-Catalyzed Regio-and Diastereoselective Steroid Hydroxylation: Efficient Directed Evolution Enabled by Mutability Landscaping ', ACS Catalysis, vol. 8, no. 4, pp. 3395-3410 . https://doi.org/10.1021/acscatal.8b00389
Cytochrome P450 monooxygenases play a crucial role in the biosynthesis of many natural products and in the human metabolism of numerous pharmaceuticals. This has inspired synthetic organic and medicinal chemists to exploit them as catalysts in regio-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::376c458d57db555de36b041a9eb1e1bb
https://www.research.manchester.ac.uk/portal/en/publications/p450catalyzed-regio-and-diastereoselective-steroid-hydroxylation-efficient-directed-evolution-enabled-by-mutability-landscaping(e831d47c-8f3f-42d1-b78c-5a2e390dc964).html
https://www.research.manchester.ac.uk/portal/en/publications/p450catalyzed-regio-and-diastereoselective-steroid-hydroxylation-efficient-directed-evolution-enabled-by-mutability-landscaping(e831d47c-8f3f-42d1-b78c-5a2e390dc964).html
Autor:
Yair Goldberg, Yuval Nov
Publikováno v:
Probability in the Engineering and Informational Sciences. 29:131-145
We study mathematically a method for discovering which gene is related to a cell characteristic (“phenotype”) of interest. The method is based on RNA interference – a molecular process for gene deactivation – and on coupling the phenotype wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d5b7f591221dd97f01d8c03c4dafe8b
https://doi.org/10.1017/s0269964814000254
https://doi.org/10.1017/s0269964814000254
Autor:
Katy Halasz, Zahava Vadasz, Tharwat Haj, Lisa Kaly, Yuval Nov, Itzhak Rosner, Rula Daood, Gleb Slobodin, Michael Rozenbaum, Doron Rimar, Nizar Jiries, Nina Boulman
Publikováno v:
Arthritis & Rheumatology. 66:726-730
Objective Fibrosis is a major cause of morbidity and mortality in systemic sclerosis (SSc). Levels of lysyl oxidase (LOX), an extracellular enzyme that stabilizes collagen fibrils, have been found to be elevated in the skin of SSc patients, but have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b14a49e2cf55ee5f01d4e2d57176b35c
https://doi.org/10.1002/art.38277
https://doi.org/10.1002/art.38277