Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Yuuki Shichi"'
Autor:
Yuuki Shichi, Fujiya Gomi, Yasuko Hasegawa, Keisuke Nonaka, Seiichi Shinji, Kimimasa Takahashi, Toshiyuki Ishiwata
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Background: Most pancreatic cancers are pancreatic ductal adenocarcinomas (PDAC). Spherical morphology formed in three-dimensional (3D) cultures and the effects of anticancer drugs differ between epithelial and mesenchymal PDAC cell lines. In the hum
Externí odkaz:
https://doaj.org/article/f820c6f219084e938730943ae997de86
Autor:
Keisuke Nonaka, Kaiyo Takubo, Junko Aida, Yoriko Watai, Akiko Komatsu, Fujiya Gomi, Yuuki Shichi, Yuto Yamazaki, Toshiyuki Ishiwata, Hironobu Sasano, Tomio Arai
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
BackgroundThe number of patients with prolonged critical illness (PCI) has been increasing in many countries, and the adrenal gland plays an important role in maintaining homeostasis during PCI. Chronic disease burden is reportedly associated with sh
Externí odkaz:
https://doaj.org/article/8d3eff5b9ee346f5ba26e11f15240004
Autor:
Yuuki Shichi, Fujiya Gomi, Yoshibumi Ueda, Keisuke Nonaka, Fumio Hasegawa, Yasuko Hasegawa, Nae Hinata, Hisashi Yoshimura, Masami Yamamoto, Kimimasa Takahashi, Tomio Arai, Toshiyuki Ishiwata
Publikováno v:
Biochemistry and Biophysics Reports, Vol 32, Iss , Pp 101339- (2022)
Three-dimensional (3D) culture of cancer cells mimics the in vivo environment. Recently, we reported that pancreatic ductal adenocarcinoma (PDAC) cell lines with epithelial and mesenchymal features formed differently shaped spheres in 3D culture. How
Externí odkaz:
https://doaj.org/article/5c005926cb2e4ad599fae0a0727a0d91
Autor:
Norihiko Sasaki, Kazumi Hirano, Yuuki Shichi, Yoko Itakura, Toshiyuki Ishiwata, Masashi Toyoda
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Phenotypic switching between contractile (differentiated state) and proliferative (dedifferentiated state) vascular smooth muscle cells (VSMCs) is a hallmark of vascular remodeling that contributes to atherosclerotic diseases. Gangliosides, a group o
Externí odkaz:
https://doaj.org/article/6855753eb97e46daaa44c2f9e1904133
Autor:
Norihiko Sasaki, Seiichi Shinji, Yuuki Shichi, Toshiyuki Ishiwata, Tomio Arai, Takeshi Yamada, Goro Takahashi, Ryo Ohta, Hiromichi Sonoda, Akihisa Matsuda, Takuma Iwai, Kohki Takeda, Kazuhide Yonaga, Koji Ueda, Sho Kuriyama, Toshimitsu Miyasaka, Hiroshi Yoshida
Publikováno v:
Biochemistry and Biophysics Reports, Vol 30, Iss , Pp 101239- (2022)
Epithelial–mesenchymal transition (EMT) plays a pivotal role in cancer progression and metastasis in many types of malignancies, including colorectal cancer. Although the importance of EMT is also considered in colorectal neuroendocrine carcinoma (
Externí odkaz:
https://doaj.org/article/67c15dce15f04150a384a2098a33d490
Autor:
Fuuka Minami, Norihiko Sasaki, Yuuki Shichi, Fujiya Gomi, Masaki Michishita, Kozo Ohkusu-Tsukada, Masashi Toyoda, Kimimasa Takahashi, Toshiyuki Ishiwata
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Genetic, transcriptional, and morphological differences have been reported in pancreatic ductal adenocarcinoma (PDAC) cases. We recently found that epithelial or mesenchymal features were enhanced in three-dimensional (3D) cultures compared
Externí odkaz:
https://doaj.org/article/98c8eef5297c4fc69d1fbd8dca4302e7
Autor:
Fujiya Gomi, Norihiko Sasaki, Yuuki Shichi, Fuuka Minami, Seiichi Shinji, Masashi Toyoda, Toshiyuki Ishiwata
Publikováno v:
Heliyon, Vol 7, Iss 2, Pp e06182- (2021)
Polyvinyl alcohol (PVA) is a water-soluble synthetic polymer used in eye drops, embolization particles, and artificial cartilage. It has also been shown to cause expansion of functional multipotent self-renewing hematopoietic stem cells under serum-f
Externí odkaz:
https://doaj.org/article/10621cca69144a078c8f802ec162b1e6
Autor:
Seiichi Shinji1 s-shinji@nms.ac.jp, Yuuki Shichi2, Takeshi Yamada1, Goro Takahashi1, Ryo Ohta1, Hiromichi Sonoda1, Akihisa Matsuda1, Kazuhide Yonaga1, Takuma Iwai1, Kohki Takeda1, Koji Ueda1, Sho Kuriyama1, Toshimitsu Miyasaka1, Yoshibumi Ueda3, Norihiko Sasaki4, Kimimasa Takahashi5, Ryuji Ohashi6, Toshiyuki Ishiwata2, Tomio Arai7, Hiroshi Yoshida1
Publikováno v:
Journal of Nippon Medical School. 2022, Vol. 89 Issue 4, p368-376. 9p.
Autor:
Keisuke Nonaka, Morito Kurata, Moriaki Tachibana, Akiko Komatsu, Yuuki Shichi, Fujiya Gomi, Toshiyuki Ishiwata, Kou Miyamoto, Tomio Arai
Publikováno v:
Pathology international.
Autor:
Norihiko, Sasaki, Kazumi, Hirano, Yuuki, Shichi, Fujiya, Gomi, Hisashi, Yoshimura, Akira, Matsushita, Masashi, Toyoda, Toshiyuki, Ishiwata
Publikováno v:
Cancers. 14(9)
Signaling pathways involving signal transducer and activator of transcription 3 (STAT3) play key roles in the aggressiveness of pancreatic ductal adenocarcinoma (PDAC), including their tumorigenesis, invasion, and metastasis. Cancer stem cells (CSCs)