Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Yuuki Nagao"'
Autor:
Maki Iwahashi, Shuichi Ohuchida, Michiyoshi Kobayashi, Yuuki Nagao, Masaaki Toda, Atsushi Naganawa, Masatoshi Koketsu, Hiromu Egashira, Tetsuji Saito, Kigen Kondo, Tohru Kambe, Hiroshi Yamamoto, Takayuki Maruyama, Hisao Nakai
Publikováno v:
Bioorganic & Medicinal Chemistry. 14:5562-5577
A series of 4-({2-[alkyl(phenylsulfonyl)amino]phenoxy}methyl)benzoic acids were identified as functional PGE 2 antagonists with selectivity for the EP1 receptor subtype starting from a chemical lead 1 , which was found while screening our in-house co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6afb5c5cb186828ec1438a7001512c32
https://doi.org/10.1016/j.bmc.2006.04.038
https://doi.org/10.1016/j.bmc.2006.04.038
Autor:
Masanori Kawamura, Kazuhiko Senokuchi, Yuuki Nagao, Hisao Nakai, Yasuhiro Sakai, Nobuo Katsube
Publikováno v:
Bioorganic & Medicinal Chemistry. 6:441-463
A series of (4 S )-4-[(2 S )-benzyl-3-mercaptopropionylamino]-4-( N -phenylcarbamoyl)-butyric acids has been identified as potent systemically active enkephalinase inhibitors. Structure–activity relationships (SAR) are discussed. Further chemical m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::144421cb1178e2a432104add6b346611
https://doi.org/10.1016/s0968-0896(97)10048-7
https://doi.org/10.1016/s0968-0896(97)10048-7
Autor:
Masanori Kawamura, Yoshisuke Nakayama, Okada Takanori, Katsuhiro Imaki, Takaaki Amino, Yasuhiro Sakai, Kaoru Kobayashi, Tetsuya Mohri, Hisao Nakai, Yuuki Nagao
Publikováno v:
Bioorganic & Medicinal Chemistry. 4:2115-2134
A novel series of pivaloyloxy benzene derivatives has been identified as potent and selective human neutrophil elastase (HNE) inhibitors. Convergent syntheses were developed in order to identify the inhibitors which are intravenously effective in an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0134614e78e51916a0b73a447fe37018
https://doi.org/10.1016/s0968-0896(96)00216-7
https://doi.org/10.1016/s0968-0896(96)00216-7
Autor:
Yuuki Nagao, Nobuyuki Hamanaka, Kanji Takahashi, Sumikazu Hamada, Kigen Kondo, Kazuhiko Torisu, Hitoshi Kato, Satoshi Shigeoka, Hidekado Tokumoto
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 5:1087-1090
By incorporation of a pyridine moiety into compounds shown to be PGI 2 agonists, we have synthesized a series of compounds which also show potent thromboxane synthase inhibitory activity. Agents 9 and 14 with the 3-substituted pyridine moiety show a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cbc1cccc20a2e8c0cb40751e24554aeb
https://doi.org/10.1016/0960-894x(95)00171-o
https://doi.org/10.1016/0960-894x(95)00171-o
Autor:
Nobuyuki Hamanaka, Kanji Takahashi, Yuuki Nagao, Kazuhiko Torisu, Hideo Takada, Hidekado Tokumoto, Kigen Kondo
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 5:1071-1076
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd2ebb7b8c0b90d3cbd9fcb12850ddd1
https://doi.org/10.1016/0960-894x(95)00168-s
https://doi.org/10.1016/0960-894x(95)00168-s
Autor:
Hidekado Tokumoto, Kigen Kondo, Nobuyuki Hamanaka, Kazuhiko Torisu, Kanji Takahashi, Yuuki Nagao
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 5:1065-1070
Syntheses of novel prostaglandin (PG) mimetics without PG skeleton are described, and the structure-activity relationships are discussed. Highly potent compounds could be obtained when the PG analog 3 was modified by removing and reconstructing the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89331e78373208a41fef7caf19aefa3f
https://doi.org/10.1016/0960-894x(95)00167-r
https://doi.org/10.1016/0960-894x(95)00167-r
Autor:
Naoya Matsumura, Hisao Nakai, Kensuke Kusumi, Tetsuo Obitsu, Akihiro Kishi, Takashi Kondo, Seishi Katsumata, Yoshifumi Kagamiishi, Yuuki Nagao, Toshiaki Matsui, Sonoko Ueno, Masaaki Toda, Tetsuji Saito
Publikováno v:
Bioorganicmedicinal chemistry. 19(18)
To identify an orally active corticotropin-releasing factor 1 receptor antagonist, a series of 6,7-dihydro-5H-cyclopenta[d]pyrazolo[1,5-a]pyrimidines and their derivatives were designed, synthesized and evaluated. An in vitro study followed by in viv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b2c1e0abce27bc668f2ff1105048a92
https://pubmed.ncbi.nlm.nih.gov/21865047
https://pubmed.ncbi.nlm.nih.gov/21865047
Publikováno v:
The proceedings of the JSME annual meeting. :49-50
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8bbb91d9ec06c773d6abe04b6d6b095
https://doi.org/10.1299/jsmemecjo.2000.1.0_49
https://doi.org/10.1299/jsmemecjo.2000.1.0_49
Publikováno v:
HETEROCYCLES. 42:517
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0113270b0698dcd84014accf0a1ad5b
https://doi.org/10.3987/com-95-s83
https://doi.org/10.3987/com-95-s83
Autor:
Yaowatat Boongla, Walaiporn Orakij, Yuuki Nagaoka, Ning Tang, Kazuichi Hayakawa, Akira Toriba
Publikováno v:
Asian Journal of Atmospheric Environment, Vol 11, Iss 4, Pp 283-299 (2017)
An analytical method using high-performance liquid chromatography (HPLC) with fluorescence (FL) detection was developed for simultaneously analyzing 10 polycyclic aromatic hydrocarbons (PAHs) and 18 nitro-derivatives of PAHs (NPAHs). The two-dimensio
Externí odkaz:
https://doaj.org/article/ae2f6f17427743e987203e1e4cb8869c