Zobrazeno 1 - 10 of 92 pro vyhledávání: '"Yuto Sumida"'
1
Akademický článek
Reverse mutants of the catalytic 19 kDa mutant protein (nanoKAZ/nanoLuc) from Oplophorus luciferase with coelenterazine as preferred substrate
Autor: Satoshi Inouye, Jun-ichi Sato, Yuiko Sahara-Miura, Yuri Tomabechi, Yuto Sumida, Shun-ichi Sekine, Mikako Shirouzu, Takamitsu Hosoya
Publikováno v: PLoS ONE, Vol 17, Iss 9 (2022)
Native Oplophorus luciferase (OpLase) and its catalytic 19 kDa protein (wild KAZ) show highest luminescence activity with coelenterazine (CTZ) among CTZ analogs. Mutated wild KAZ with 16 amino acid substitutions (nanoKAZ/nanoLuc) utilizes bis-coelent
Externí odkaz: https://doaj.org/article/0ab9804ceac14a5fa5afb2bd5e36d483
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3
Akademický článek
Chiral deaza-coelenterazine analogs for probing a substrate-binding site in the Ca2+-binding photoprotein aequorin.
Autor: Satoshi Inouye, Yuto Sumida, Yuri Tomabechi, Jumpei Taguchi, Mikako Shirouzu, Takamitsu Hosoya
Publikováno v: PLoS ONE, Vol 16, Iss 6, p e0251743 (2021)
The Ca2+-binding photoprotein aequorin is a complex of apoAequorin (apoprotein) and (S)-2-peroxycoelenterazine. Aequorin can be regenerated by the incubation of apoAequorin with coelenterazine and molecular oxygen (O2). In this study, to investigate
Externí odkaz: https://doaj.org/article/3249aef8b5a3499cbe153a480cac8bb5
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6
meta-Selective Radical Acylation of Electron-rich Arenes
Autor: Yamato Goto, Masaki Sano, Yuto Sumida, Hirohisa Ohmiya
meta-Selective functionalisation of electron-rich arenes provides a non-traditional route to organic synthesis. In classical electrophilic aromatic substitution of electron-donating group-pendant arenes, functionalisation occurs according to ortho- a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f4d0a75485a7178773aa05f913b530d1
https://doi.org/10.26434/chemrxiv-2023-1p1kv
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7
Akademický článek
Selective inhibition of the kinase DYRK1A by targeting its folding process
Autor: Isao Kii, Yuto Sumida, Toshiyasu Goto, Rie Sonamoto, Yukiko Okuno, Suguru Yoshida, Tomoe Kato-Sumida, Yuka Koike, Minako Abe, Yosuke Nonaka, Teikichi Ikura, Nobutoshi Ito, Hiroshi Shibuya, Takamitsu Hosoya, Masatoshi Hagiwara
Publikováno v: Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
Kinase inhibitors are important drugs and usually target the ATP binding pocket of kinases. Here, Kii et al.report a completely new type of kinase inhibitor that specifically targets the protein folding intermediate state, but not the mature form, of
Externí odkaz: https://doaj.org/article/cc58fcf33b4145468837fef116260032
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9
Akademický článek
An Alternative Method for Generating Arynes from ortho-Silylaryl Triflates: Activation by Cesium Carbonate in the Presence of a Crown Ether
Autor: Suguru Yoshida, Yuki Hazama, Yuto Sumida, Takahisa Yano, Takamitsu Hosoya
Publikováno v: Molecules, Vol 20, Iss 6, Pp 10131-10140 (2015)
An alternative method for generating arynes from ortho-silylaryl triflates using cesium carbonate and 18-crown-6 is reported. The method was efficiently applied to a variety of reactions between several arynes and arynophiles. We also demonstrated th
Externí odkaz: https://doaj.org/article/3d33106e9e31471cb410c54b358c9922
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10
Aliphatic Oxaboroles Enabling Remarkable Recognition of Diols
Autor: Fuyuhiko Inagaki, Yuto Sumida, Kazunori Nagao, Hiroshi Arakawa, Nozomi Arakawa, Ryo Murakami, Hirohisa Ohmiya
Publikováno v: Bulletin of the Chemical Society of Japan. 93:576-580
5-Membered ring aliphatic oxaboroles revealed unique characteristics in their reactivity with diols. The aliphatic oxaborole derivatives exhibited a higher complexation activity for Alizarin Red S ...
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d38827ca07027081c013ee33c4d9ca43
https://doi.org/10.1246/bcsj.20200007
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