Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Yutaro Yamaoka"'
Autor:
Mayuko Nishi, Kensuke Tateishi, Jeremiah Stanleyraj Sundararaj, Yoko Ino, Yusuke Nakai, Yasuyoshi Hatayama, Yutaro Yamaoka, Yusaku Mihana, Kei Miyakawa, Hirokazu Kimura, Yayoi Kimura, Tetsuya Yamamoto, Akihide Ryo
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Primary central nervous system lymphoma (PCNSL) is a malignant neoplasm of the central nervous system that is refractory to treatment and has extremely poor prognosis. One factor hindering the development of therapeutic options for PCNSL is its molec
Externí odkaz:
https://doaj.org/article/ffce3162537d44a9adbbf36038cf9924
Autor:
Kayoko Nagata, Daichi Utsumi, Masamitsu N. Asaka, Ryota Maeda, Kotaro Shirakawa, Yasuhiro Kazuma, Ryosuke Nomura, Yoshihito Horisawa, Yohei Yanagida, Yugo Kawai, Kei Sato, Yutaro Yamaoka, Kei Miyakawa, Akihide Ryo, Yasuhiro Yasutomi, Akihiro Imura, Akifumi Takaori-Kondo
Publikováno v:
Communications Medicine, Vol 2, Iss 1, Pp 1-6 (2022)
Nagata, Utsumi, Asaka, Maeda et al. describe a nanobody, TP86, that potently neutralizes both BA.1 and BA.2 Omicron SARS-CoV-2 variants, and, when combined with the TP17 nanobody, broadly neutralizes all SARS-CoV-2 variants. This nanobody cocktail al
Externí odkaz:
https://doaj.org/article/10418e3e410846ef990c3a56f313ff36
Autor:
Ryota Maeda, Junso Fujita, Yoshinobu Konishi, Yasuhiro Kazuma, Hiroyuki Yamazaki, Itsuki Anzai, Tokiko Watanabe, Keishi Yamaguchi, Kazuki Kasai, Kayoko Nagata, Yutaro Yamaoka, Kei Miyakawa, Akihide Ryo, Kotaro Shirakawa, Kei Sato, Fumiaki Makino, Yoshiharu Matsuura, Tsuyoshi Inoue, Akihiro Imura, Keiichi Namba, Akifumi Takaori-Kondo
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-16 (2022)
A panel of nanobodies are presented that can detect the spike proteins of five SARS-CoV-2 variants of concern and structural analyses show that one clone targets conserved epitopes on the receptor-binding domain and contacts the N-terminal domain.
Externí odkaz:
https://doaj.org/article/ebff1ac040bc4897b219b41bbbf0ca49
Autor:
Shigeta Miyake, Takuma Higurashi, Hideaki Kato, Yutaro Yamaoka, Takaomi Kessoku, Shingo Kato, Fumihiro Ogawa, Yasufumi Oi, Atsushi Nakajima, Tetsuya Yamamoto, Ichiro Takeuchi, Akihide Ryo, Shin Maeda
Publikováno v:
Journal of Infection and Public Health, Vol 14, Iss 9, Pp 1212-1217 (2021)
Background: Many health care workers around the world tackled with COVID-19, however sadly, the infection of many medical care workers were reported. To reduce the risk of infection, we launched selected team (Team COVID) of non-specialists and broug
Externí odkaz:
https://doaj.org/article/8062b9e265434af79839163a5bba08dc
Autor:
Kei Miyakawa, Sundararaj Stanleyraj Jeremiah, Yutaro Yamaoka, Takahiko Koyama, Reitaro Tokumasu, Michiharu Kudo, Hideaki Kato, Akihide Ryo
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
The successive emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants has presented a major challenge in the management of the coronavirus disease (COVID-19) pandemic. There are growing concerns regarding the emerging vari
Externí odkaz:
https://doaj.org/article/10b65debf1594836beb7e7424df7a29d
Autor:
Yusuke Nakai, Kei Miyakawa, Yutaro Yamaoka, Yasuyoshi Hatayama, Mayuko Nishi, Hidefumi Suzuki, Hirokazu Kimura, Hidehisa Takahashi, Yayoi Kimura, Akihide Ryo
Publikováno v:
Microorganisms, Vol 10, Iss 12, p 2381 (2022)
Hepatitis B virus (HBV) core antigen (HBc) is a structural protein that forms the viral nucleocapsid and is involved in various steps of the viral replication cycle, but its role in the pathogenesis of HBV infection is still elusive. In this study, w
Externí odkaz:
https://doaj.org/article/3c7b1c3dd4f649a7bcadb10f8174259f
Autor:
Yasuyoshi Hatayama, Yutaro Yamaoka, Takeshi Morita, Sundararaj Stanleyraj Jeremiah, Kei Miyakawa, Mayuko Nishi, Yayoi Kimura, Makoto Mitsunaga, Tadayuki Iwase, Hirokazu Kimura, Naoki Yamamoto, Akifumi Takaori-Kondo, Hideki Hasegawa, Akihide Ryo
Publikováno v:
Viruses, Vol 14, Iss 10, p 2153 (2022)
Human T-cell leukemia virus type 1 (HTLV-1), a retrovirus, causes adult T-cell leukemia-lymphoma, HTLV-1 associated myelopathy/tropical spastic paraparesis, and HTLV-1 uveitis. Currently, no antiretroviral therapies or vaccines are available for HTLV
Externí odkaz:
https://doaj.org/article/eed65c7af9ef4378ad9b368b590f0c2e
Autor:
Yutaro Yamaoka, Kei Miyakawa, Sundararaj Stanleyraj Jeremiah, Rikako Funabashi, Koji Okudela, Sayaka Kikuchi, Junichi Katada, Atsuhiko Wada, Toshiki Takei, Mayuko Nishi, Kohei Shimizu, Hiroki Ozawa, Shuzo Usuku, Chiharu Kawakami, Nobuko Tanaka, Takeshi Morita, Hiroyuki Hayashi, Hideaki Mitsui, Keita Suzuki, Daisuke Aizawa, Yukihiro Yoshimura, Tomoyuki Miyazaki, Etsuko Yamazaki, Tadaki Suzuki, Hirokazu Kimura, Hideaki Shimizu, Nobuhiko Okabe, Hideki Hasegawa, Akihide Ryo
Publikováno v:
Cell Reports Medicine, Vol 2, Iss 6, Pp 100311- (2021)
Summary: The ongoing coronavirus disease 2019 (COVID-19) pandemic is a major global public health concern. Although rapid point-of-care testing for detecting viral antigen is important for management of the outbreak, the current antigen tests are les
Externí odkaz:
https://doaj.org/article/fb0452d89f3141f5bf9c15493667baf5
Autor:
Yoji Ikuta, Kunihiro Oba, Emina Nai, Tatsuo Katori, Masanori Hashino, Yuba Inamine, Satoko Matsunaga, Yutaro Yamaoka, Tsuyoshi Sekizuka, Akihide Ryo, Makoto Kuroda
Publikováno v:
Journal of Medical Case Reports, Vol 13, Iss 1, Pp 1-4 (2019)
Abstract Background Torque teno virus-induced aseptic meningitis has not been documented, although torque teno virus infections still remain under consideration for etiological agents. This study identified a torque teno virus sequence using next gen
Externí odkaz:
https://doaj.org/article/51edf4c5c94a4805a786dc4fdb1c24c9
Autor:
Yutaro Yamaoka, Sundararaj Stanleyraj Jeremiah, Rikako Funabashi, Kei Miyakawa, Takeshi Morita, Yusaku Mihana, Hideaki Kato, Akihide Ryo
Publikováno v:
Viruses, Vol 14, Iss 7, p 1461 (2022)
The spike protein (SP) of SARS-CoV-2 is an important target for COVID-19 therapeutics and vaccines as it binds to the ACE2 receptor and enables viral infection. Rapid production and functional characterization of properly folded SP is of the utmost i
Externí odkaz:
https://doaj.org/article/7c4003c4cf0c41999e91569d20958d5e