Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Yutaro KUBO"'
Autor:
Shoji HIRAHARA, Yutaro KUBO, Takuma YOSHIDA, Takuya KOMORI, Jotaro CHIBA, Toshinari TAKAKURA, Takafumi KANEHAMA, Ryohei SEKIGUCHI, Kenta OCHI, Hiroyuki SUGIMOTO, Yukimasa ADACHI, Ichiro ISHIKAWA, Yosuke FUJII
Publikováno v:
Journal of the Meteorological Society of Japan. Ser. II. 101:149-169
Autor:
Manabu Shiozawa, Yu Sunakawa, Takanori Watanabe, Hirofumi Ota, Hisateru Yasui, Taichi Yabuno, Mitsuyoshi Tei, Mitsugu Kochi, Dai Manaka, Hisatsugu Ohori, Tatsuro Yamaguchi, Tamotsu Sagawa, Masahito Kotaka, Yutaro Kubota, Takashi Sekikawa, Masato Nakamura, Masahiro Takeuchi, Wataru Ichikawa, Masashi Fujii, Akihito Tsuji
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-9 (2024)
Abstract The clinical significance of FOLFOXIRI (5-FU, leucovorin, oxaliplatin, and irinotecan) plus anti-EGFR monoclonal antibody using cetuximab for metastatic colorectal cancer (mCRC) remains controversial. We report results from a randomized phas
Externí odkaz:
https://doaj.org/article/c5c30590bce046fe8b38d53091cad924
Autor:
Yuya Hirasawa, Yutaro Kubota, Emiko Mura, Risako Suzuki, Toshiaki Tsurui, Nana Iriguchi, Tomoyuki Ishiguro, Ryotaro Ohkuma, Masahiro Shimokawa, Hirotsugu Ariizumi, Atsushi Horiike, Satoshi Wada, Takeshi Yamashita, Tomotake Ariyoshi, Satoru Goto, Koji Otsuka, Masahiko Murakami, Yuji Kiuchi, Kiyoshi Yoshimura, Takuya Tsunoda
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionImmune checkpoint inhibitors (ICIs) have emerged as a promising treatment option for esophageal cancer (EC). Although ICIs enable long-term survival in some patients, the efficacy of ICIs varies widely among patients. Therefore, predictiv
Externí odkaz:
https://doaj.org/article/ec9c13c60c4d45eb834f44c57b5372fe
Autor:
Masakazu Murayama, Masahiro Hosonuma, Atsuo Kuramasu, Sei Kobayashi, Akiko Sasaki, Yuta Baba, Yoichiro Narikawa, Hitoshi Toyoda, Junya Isobe, Eiji Funayama, Kohei Tajima, Aya Sasaki, Yuki Maruyama, Yoshitaka Yamazaki, Midori Shida, Kazuyuki Hamada, Yuya Hirasawa, Toshiaki Tsurui, Hirotsugu Ariizumi, Tomoyuki Ishiguro, Risako Suzuki, Ryotaro Ohkuma, Yutaro Kubota, Atsushi Horiike, Takehiko Sambe, Mayumi Tsuji, Satoshi Wada, Shinichi Kobayashi, Toshikazu Shimane, Takuya Tsunoda, Hitome Kobayashi, Yuji Kiuchi, Kiyoshi Yoshimura
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract The low response rate of immune checkpoint inhibitors (ICIs) is a challenge. The efficacy of ICIs is influenced by the tumour microenvironment, which is controlled by the gut microbiota. In particular, intestinal bacteria and their metabolit
Externí odkaz:
https://doaj.org/article/7f87f822bfdf411aabf1cc2f6ca5007b
Publikováno v:
SOLA; 2023, Vol. 19, p282-288, 7p
Autor:
Ken‐ichi Fujita, Natsumi Matsumoto, Remi Murase, Kosuke Takeshima, Hiroo Ishida, Yutaro Kubota
Publikováno v:
Clinical and Translational Science, Vol 16, Iss 10, Pp 1741-1747 (2023)
Abstract Regorafenib improves the survival of patients with metastatic colorectal cancer (mCRC); however, it is also characterized by detrimental dermal side effects that may require treatment cessation or modified dosing. In our previous prospective
Externí odkaz:
https://doaj.org/article/d0852674197946e3aea5afc90a221a27
Publikováno v:
Atmospheric Science Letters. 18:330-335
We investigated mechanisms contributing to the quiescent tropical cyclone (TC) activity in the western North Pacific (WNP) during the early summer (May–July) of 2016 by conducting and analysing seasonal predictions and sensitivity experiments with
Autor:
Akihiko Shimpo, Hiroyuki Sugimoto, Satoko Matsueda, Shoji Hirahara, Chihiro Matsukawa, Tomoaki Ose, Yuhei Takaya, Takahiro Toyoda, Shuhei Maeda, Ryoji Nagasawa, Ichiro Ishikawa, Hirotoshi Mori, Yosuke Fujii, Goro Yamanaka, Yutaro Kubo, Noriyuki Adachi, Tsurane Kuragano, Tamaki Yasuda
Publikováno v:
Climate Dynamics. 50:751-765
This paper describes the Japan Meteorological Agency/Meteorological Research Institute-Coupled Prediction System version 2 (JMA/MRI-CPS2), which was put into operation in June 2015 for the purpose of performing seasonal predictions. JMA/MRI-CPS2 has
Publikováno v:
SOLA. 13:120-124
Autor:
Koya Obara, Jose Reynoso, Yuko Hamada, Yusuke Aoki, Yutaro Kubota, Noriyuki Masaki, Yasuyuki Amoh, Robert M. Hoffman
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Stimulation of hair growth in hair loss has been a difficult goal to achieve. Hair follicle-associated pluripotent (HAP) stem cells express nestin and have been shown to differentiate to multiple cell types including keratinocytes, neurons,
Externí odkaz:
https://doaj.org/article/99609dc74f7f42f284f939019321b60a