Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Yutao Xiu"'
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 39, Iss 1 (2024)
AbstractA series of cis-restricted 3-aryl-4-(3,4,5-trimethoxyphenyl)pyridines as novel tubulin polymerisation inhibitors was designed based on molecular docking. Compound 9p, exhibited potent antiproliferative activity against HeLa, MCF-7, and A549 c
Externí odkaz:
https://doaj.org/article/20346a9d73e8457f95d03cd1b57f851a
Publikováno v:
Frontiers in Chemistry, Vol 12 (2024)
In this work, a series of new diarylpyrimidine derivatives as microtubule destabilizers were designed, synthesized, and evaluated for anticancer activities. Based on restriction configuration strategy, we introduced the pyrimidine moiety containing t
Externí odkaz:
https://doaj.org/article/4ac1e4ba7c8f4174af36c6238eba83e3
Publikováno v:
Arabian Journal of Chemistry, Vol 16, Iss 10, Pp 105146- (2023)
Some novel 4-aryl-9H-carbazoles were designed as potential tubulin polymerization inhibitors through structural optimization and bioisosteric strategy. These compounds showed effective antiproliferative activities against a diverse set of cancer cell
Externí odkaz:
https://doaj.org/article/fef20283db844083b3465c663f87a13c