Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Yutaka Kokubo"'
Autor:
Yuji Minegishi, Yutaka Kokubo, Masahiro Seike, Tetsuya Okano, Masahiko Shibuya, Rintaro Noro, Akihiko Gemma, Shouji Kudoh, Akinobu Yoshimura, Kiyoko Kataoka, Kuniko Matsuda
Publikováno v:
British Journal of Cancer
Gefitinib (IRESSA), an epidermal growth factor receptor (EGFR) tyrosine kinase (TK) inhibitor, has antitumour activity in the advanced non-small-cell lung cancer (NSCLC) setting. However, in chemotherapy-naïve patients with advanced NSCLC, the addit
Autor:
Michiya Nara, Rintaro Noro, Masahiro Seike, Kiyoko Kataoka, Yutaka Kokubo, Akihiko Miyanaga, Akinobu Yoshimura, Yuji Minegishi, Akihiko Gemma, Tetsuya Okano, Shoji Kudoh, Kuniko Matsuda, Seiji Kosaihira
Publikováno v:
International Journal of Oncology.
To understand the mechanisms of PTEN inactivation, which is reported to be involved in tumor progression and drug resistance in lung cancer, we analyzed the expression levels of PTEN at mRNA and protein levels, along with the genetic and epigenetic s
Autor:
Akihiko, Gemma, Masahiro, Seike, Seiji, Kosaihira, Yuji, Minegishi, Rintaro, Noro, Michiya, Nara, Yukio, Hosomi, Tetsuya, Okano, Yutaka, Kokubo, Akinobu, Yoshimura, Masahiko, Shibuya, Shoji, Kudoh
Publikováno v:
Anticancer research. 26(4B)
A gene-drug correlation analysis was previously performed in lung cancer cell lines using the NC160 program. On the basis of this work, a phase I/II pilot study of weekly paclitaxel and carboplatin (CBDCA) was subsequently planned for refractory or r
Autor:
Akinobu Yoshimura, Yutaka Kokubo, Yukio Hosomi, Makoto Nagashima, Yoko Hosoya, Michiya Nara, Tetsuya Okano, Shoji Kudoh, Curtis C. Harris, Masahiko Shibuya, Akihiko Gemma
Publikováno v:
Oncology Reports.
The ING1 gene is involved in the regulation of the cell cycle, senescence, and apoptosis and is a novel candidate tumor suppressor gene. ING2, another gene in the ING family, was identified and cloned. The functions of ING1 and ING2 largely depend on
Autor:
Akinobu Yoshimura, Masahiro Seike, Yoko Hosoya, Kiyoko Kataoka, Akihiko Gemma, Shoji Kudoh, Rintaroh Noro, Yutaka Kokubo, Masatoshi Watanabe
Publikováno v:
Journal of Nippon Medical School = Nippon Ika Daigaku zasshi. 71(2)
Allelic deletion at chromosome 8p21-25 is an early and frequent event in the carcinogenesis and development of various cancers. To facilitate investigation of alterations of the macrophage scavenger receptor 1 (MSR1), which is located on 8p22, and to
Autor:
Mitsunori, Hino, Yasushi, Ono, Yutaka, Kokubo, Tomoyuki, Soma, Yosuke, Tanaka, Takashi, Uehara, Ritsuko, Narato, Yoko, Yoshioka, Shoji, Kudo
Publikováno v:
The Japanese journal of antibiotics. 56
Autor:
Yosuke Tanaka, Yutaka Kokubo, Takashi Uehara, Tomoyuki Soma, Yasushi Ono, Mitsunori Hino, Shoji Kudoh
Publikováno v:
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy. 10(3)
Our aim was to evaluate the effects of eradication and the incidence of secondary resistance by long-term low-dose daily 14-membered-ring macrolide therapy on Helicobacter pylori ( H. pylori) infection in patients with chronic lower respiratory tract
Autor:
Shoji Kudoh, Yasushi Ono, Kuniko Matsuda, Suguru Hibino, Kinya Shinoda, Datong Zou, Akira Takemura, Akiko Takechi, Yutaka Kokubo, Masahiko Shibuya
Publikováno v:
International journal of oncology. 22(2)
The matrix metalloproteinases (MMPs) are likely to contribute to tumor cell invasion, metastasis and angiogenesis. Several MMP inhibitors have been developed, recently and their anti-tumor efficacy is being evaluated in clinical trials. FYK-1388 is a
Autor:
Mitsunori, Hino, Yasushi, Ono, Yutaka, Kokubo, Tomoyuki, Soma, Yousuke, Tanaka, Masatoshi, Omata, Kozo, Ichino, Takashi, Uehara, Shoji, Kudoh, Naoaki, Hayama
Publikováno v:
Kekkaku : [Tuberculosis]. 77(4)
In 1998, Prevention Committee of the Japanese Society for Tuberculosis announced guidelines for dealing with nosocomial tuberculosis infections. These guidelines recommended the two-step tuberculin tests (TST) as baseline data for each medical employ
Publikováno v:
Annals of Oncology. 23:xi156
Background The Calvert formula is routinely applied for the dosing of carboplatin based on glomerular filtration rate (GFR) as accurately measured using the 51-Cr-EDTA clearance. In general practice, an estimated value of creatinine clearance calcula