Výsledky vyhledávání - "Yutaka Kariya"

Generation and characterization of a series of monoclonal antibodies that specifically recognize [HexA(±2S)-GlcNAc]n epitopes in heparan sulfate

Autor: Yutaka Kariya, Mamoru Kyogashima, Kiyoshi Suzuki, Reiji Kannagi, Eun Ji Joo, Koji Kimata, Yeong Shik Kim, Shuichi Miyaura, Koji Yamamoto, Hiroshi Maeda, Takeshi Ishimaru, Akiko Yusa, Masahiro Fujii

Publikováno v: Glycoconjugate Journal. 25:703-712

Five monoclonal antibodies AS17, 22, 25, 38 and 48, a single monoclonal antibody ACH55, and three monoclonal antibodies NAH33, 43, 46, that recognize acharan sulfate (IdoA2S-GlcNAc)n, acharan (IdoA-GlcNAc)n and N-acetyl-heparosan (GlcA-GlcNAc)n, resp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15ab593810796d921f1f3ebbca0f5223
https://doi.org/10.1007/s10719-008-9130-z

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Heparin Regulates Vascular Endothelial Growth Factor165-dependent Mitogenic Activity, Tube Formation, and Its Receptor Phosphorylation of Human Endothelial Cells

Autor: Koji Kimata, Satoko Ashikari-Hada, Yutaka Kariya, Hiroko Habuchi

Publikováno v: Journal of Biological Chemistry. 280:31508-31515

Vascular endothelial growth factor (VEGF) is a family of glycoproteins with potent angiogenic activity. We reported previously that heparin has an affinity for VEGF165, the major isoform of VEGF, whereas 2-O-desulfated heparin and 6-O-desulfated hepa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ea8ee8c556cf1ebbafc7ae068c9db6f0
https://doi.org/10.1074/jbc.m414581200

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Effects of heparin and its 6-O-and 2-O-desulfated derivatives with low anticoagulant activity on proliferation of human neural stem/progenitor cells

Autor: Jun Miyake, Junichi Onaya, Yonehiro Kanemura, Masayuki Hara, Hideki Mori, Mami Yamasaki, Yutaka Kariya

Publikováno v: Journal of Bioscience and Bioengineering. 100:54-61

Heparin binds various growth factors and activates them to interact with high-affinity cell surface receptors; a specific array of sulfate groups in the heparin backbone structure is very important for this interaction. In the present study, we evalu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a7eefa0538f5ea8d909c30dd2daf760
https://doi.org/10.1263/jbb.100.54

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Heparin structures in FGF-2-dependent morphological transformation of astrocytes

Autor: Ryo Takano, Toshie Nagayasu, Kaeko Kamei, Noriko Hayashi, Seiji Miyata, Yutaka Kariya

Publikováno v: Journal of Biomedical Materials Research Part A. :374-380

Fibroblast growth factor-2 (FGF-2) participates in the morphological transformation of astrocytes (stellation) during the formation of glial scars in injured brains. In the current study, we used quantitative morphometric analysis to investigate the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::350babe37c5b3bcfa924142cb1ba0762
https://doi.org/10.1002/jbm.a.30338

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Isolation and partial characterization of fucan sulfates from the body wall of sea cucumber Stichopus japonicus and their ability to inhibit osteoclastogenesis

Autor: Tadashi Ishii, Akihiro Tominaga, Yutaka Kariya, Kiyoshi Suzuki, Akira Asari, Takuji Kaneko, Barbara Mulloy, Mamoru Kyogashima, Hiroyuki Masuda, Kyoko Imai

Publikováno v: Carbohydrate Research. 339:1339-1346

Two types of fucan sulfate were isolated from chloroform/methanol extract of the body wall of the sea cucumber Stichopus japonicus. One type (type A) contained 3.41 mmol fucose/g and 2.35 mmol sulfate/g, and the molecular mass was determined to be 9

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20283c102620f701dab533311a57b848
https://doi.org/10.1016/j.carres.2004.02.025

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Modification of di- and tetrasaccharides from shark cartilage keratan sulphate by refined anhydromethanolic hydrochloric acid-treatments and evaluation of their specific desulphation

Autor: Yutaka Kariya, Hideo Mochizuki, Shugo Watabe, Mamoru Kyogashima, Hiroshi Kikuchi, Kiyoshi Suzuki, Tadashi Ishii, Kyoko Imai

Publikováno v: Carbohydrate Research. 338:1133-1138

Highly sulphated keratan di- and tetrasaccharides were prepared from keratan sulphate (KS) of shark cartilage by enzymatic digestion with keratanase II and subsequent chromatography. The tetrasaccharide fraction carrying four sulphate groups was comp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3800b2b642f69bbfa2064b1dc84bce2e
https://doi.org/10.1016/s0008-6215(03)00068-5

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Enhancement of t-PA-Mediated Plasminogen Activation by Partially Defucosylated Glycosaminoglycans from the Sea Cucumber Stichopus japonicus

Autor: Yutaka Kariya, Takuji Kaneko, Kiyoshi Suzuki, Mamoru Kyogashima, Tokiko Sakai

Publikováno v: Journal of Biochemistry. 132:335-343

Sea cucumber glycosaminoglycan (SC-GAG) was isolated from the body wall of the sea cucumber Stichopus japonicus. The SC-GAG consists of a chondroitin sulfate E-type core polymer with sulfated fucose branches attaching glycosidically to almost every d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bab03df8132b07f333a02badafd0147
https://doi.org/10.1093/oxfordjournals.jbchem.a003228

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Fructose 1,6-Bisphosphate Aldolase Is a Heparin-Binding Protein

Autor: Thanh-Van Ta, Kaeko Kamei, Yutaka Kariya, Xin-Yan Xu, Keiichi Yoshida, Ryo Takano, Saburo Hara

Publikováno v: Journal of Biochemistry. 125:554-559

Proteins with affinity to heparin under physiological conditions were isolated from bovine cerebral cortex. First, the extract of cerebral cortex was applied to a chondroitin polysulfate column under physiological conditions. Then, the pass-through f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c94542856b2aa33ac67d2594da1e4afd
https://doi.org/10.1093/oxfordjournals.jbchem.a022320

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Structure of fucose branches in the glycosaminoglycan from the body wall of the sea cucumber Stichopus japonicus

Autor: Yutaka Kariya, Tadashi Ishii, Masayuki Ishihara, Shugo Watabe, Mamoru Kyogashima

Publikováno v: Carbohydrate Research. 297:273-279

Fucose-branched chondroitin sulfate E was prepared from the body wall of sea cucumber Stichopus japonicus. The purified glycosaminoglycan (GAG) was chemically desulfated, followed by carboxyl reduction. Intact, desulfated, and desulfated/carboxyl-red

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3547ffceb4f7ef25a3587e8a582977b5
https://doi.org/10.1016/s0008-6215(96)00258-3

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