Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Yuta OGASAWARA"'
Publikováno v:
Nihon Kikai Gakkai ronbunshu, Vol 88, Iss 915, Pp 22-00217-22-00217 (2022)
Low-frequency noise is difficult to suppress by passive control using a sound absorbing material. Active noise control is expected to be an effective method against low-frequency noise. Minimizing the total acoustic power emitted by a sound source ca
Externí odkaz:
https://doaj.org/article/deda7d676b134758b92c0a03998dddeb
Autor:
Yuta Ogasawara, Jinglei Cheng, Tsuyako Tatematsu, Misaki Uchida, Omi Murase, Shogo Yoshikawa, Yuki Ohsaki, Toyoshi Fujimoto
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
The source of phospholipids to generate autophagosomal membranes, particularly after prolonged starvation, is not well characterized. Here, the authors show that CCTβ3, the rate limiting enzyme in phosphatidylcholine synthesis, is activated on lipid
Externí odkaz:
https://doaj.org/article/01aa050b4596409a8597336a1d223531
Publikováno v:
Biology Open, Vol 6, Iss 1, Pp 35-40 (2017)
Macroautophagy, a major degradation pathway of cytoplasmic components, is carried out through formation of a double-membrane structure, the autophagosome. Although the involvement of specific lipid species in the formation process remains largely obs
Externí odkaz:
https://doaj.org/article/243e5b1e1fa243c78fcb64146d89df90
Autor:
Kelly Devereaux, Claudia Dall'Armi, Abel Alcazar-Roman, Yuta Ogasawara, Xiang Zhou, Fan Wang, Akitsugu Yamamoto, Pietro De Camilli, Gilbert Di Paolo
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76405 (2013)
Synthesis of phosphatidylinositol-3-phosphate (PI3P) by Vps34, a class III phosphatidylinositol 3-kinase (PI3K), is critical for the initial steps of autophagosome (AP) biogenesis. Although Vps34 is the sole source of PI3P in budding yeast, mammalian
Externí odkaz:
https://doaj.org/article/8b56b3db72484585878136091970d6c8
Autor:
Tomoyuki Fukuda, Kentaro Furukawa, Tatsuro Maruyama, Shun-ichi Yamashita, Daisuke Noshiro, Chihong Song, Yuta Ogasawara, Kentaro Okuyama, Jahangir Md Alam, Manabu Hayatsu, Tetsu Saigusa, Keiichi Inoue, Kazuho Ikeda, Akira Takai, Lin Chen, Vikramjit Lahiri, Yasushi Okada, Shinsuke Shibata, Kazuyoshi Murata, Daniel J. Klionsky, Nobuo N. Noda, Tomotake Kanki
Publikováno v:
Molecular Cell.
Publikováno v:
Cancer Science.
Autor:
Jin Cui, Yuta Ogasawara, Ikuko Kurata, Kazuaki Matoba, Yuko Fujioka, Nobuo N. Noda, Masakatsu Shibasaki, Takumi Watanabe
Publikováno v:
Journal of the American Chemical Society. 144(38)
Selective modulation of autophagy is a promising therapeutic strategy, especially for cancer treatment. However, the lack of specific autophagy inhibitors limits this strategy. The formation of the ATG12-ATG5-ATG16L1 complex is essential for targetin
Autor:
Toyoshi Fujimoto, Yuki Ohsaki, Shogo Yoshikawa, Misaki Uchida, Jinglei Cheng, Omi Murase, Yuta Ogasawara, Tsuyako Tatematsu
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communications
Nature Communications
Macroautophagy initiates by formation of isolation membranes, but the source of phospholipids for the membrane biogenesis remains elusive. Here, we show that autophagic membranes incorporate newly synthesized phosphatidylcholine, and that CTP:phospho
Autor:
Kumiko Okino, Yuta Ogasawara, Asuka Oikawa, Tomoko Kudo, Yuka Takayanagi, Masakazu Kawasaki, Minoru Kikuchi, Daiki Mitsumori, Tomo Aoki, Rie Nakamori, Hiroki Omiya, Fumiaki Terasawa
Publikováno v:
The Journal of Japanese College of Angiology. 59:105-110
Publikováno v:
The Journal of Cell Biology
Orii et al. show that phospholipids distribute symmetrically in the yeast autophagosomal membranes. They also show that de novo–synthesized phosphatidylcholine is incorporated to autophagosomal membranes preferentially and attains the symmetrical d