Zobrazeno 1 - 10 of 66 pro vyhledávání: '"Yuta MATSUOKA"'
1
Akademický článek
Identification of genes supporting cold resistance of mammalian cells: lessons from a hibernator
Autor: Masamitsu Sone, Nonoka Mitsuhashi, Yuki Sugiura, Yuta Matsuoka, Rae Maeda, Akari Yamauchi, Ryoto Okahashi, Junpei Yamashita, Kanako Sone, Sachiyo Enju, Daisuke Anegawa, Yoshifumi Yamaguchi
Publikováno v: Cell Death and Disease, Vol 15, Iss 9, Pp 1-12 (2024)
Abstract Susceptibility of human cells to cold stress restricts the use of therapeutic hypothermia and long-term preservation of organs at low temperatures. In contrast, cells of mammalian hibernators possess remarkable cold resistance, but little is
Externí odkaz: https://doaj.org/article/14d01a1aaec94330b7996575b32ed0d5
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2
Akademický článek
Construction of a screening system for lipid-derived radical inhibitors and validation of hit compounds to target retinal and cerebrovascular diseases
Autor: Ryota Mori, Masami Abe, Yuma Saimoto, Saki Shinto, Sara Jodai, Manami Tomomatsu, Kaho Tazoe, Minato Ishida, Masataka Enoki, Nao Kato, Tomohiro Yamashita, Yuki Itabashi, Ikuo Nakanishi, Kei Ohkubo, Sachiko Kaidzu, Masaki Tanito, Yuta Matsuoka, Kazushi Morimoto, Ken-ichi Yamada
Publikováno v: Redox Biology, Vol 73, Iss , Pp 103186- (2024)
Recent studies have highlighted the indispensable role of oxidized lipids in inflammatory responses, cell death, and disease pathogenesis. Consequently, inhibitors targeting oxidized lipids, particularly lipid-derived radicals critical in lipid perox
Externí odkaz: https://doaj.org/article/7d182cc53e094558b215ae9e0f93a292
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3
Akademický článek
Triglyceride peroxidation progression in lipid droplets of hepatocytes in nonalcoholic steatohepatitis
Autor: Kota Saito, Yuta Matsuoka, Masami Abe, Nao Kato, Kazushi Morimoto, Ken-ichi Yamada
Publikováno v: Redox Experimental Medicine, Vol 2023, Iss 1, Pp 1-11 (2024)
Objective: Nonalcoholic steatohepatitis is a chronic liver disease caused by the progression of hepatocellular death and inflammation from simple steatosis. However, the pathogenesis of this disease remains unclear. Lipid peroxidation is one of the m
Externí odkaz: https://doaj.org/article/ce3134d9d4eb44e6a44a8639ed4effb4
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4
Akademický článek
Structural library and visualization of endogenously oxidized phosphatidylcholines using mass spectrometry-based techniques
Autor: Yuta Matsuoka, Masatomo Takahashi, Yuki Sugiura, Yoshihiro Izumi, Kazuhiro Nishiyama, Motohiro Nishida, Makoto Suematsu, Takeshi Bamba, Ken-ichi Yamada
Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Oxidized phosphatidylcholines (oxPCs) are a structurally diverse class of lipids associated with various diseases. Here, the authors use mass spectrometry to construct a spectral library of 465 oxPCs and subsequently profile oxPCs formed during aceta
Externí odkaz: https://doaj.org/article/37bab6945355410fb3f591261ec7e897
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5
Akademický článek
Hepatic resistance to cold ferroptosis in a mammalian hibernator Syrian hamster depends on effective storage of diet-derived α-tocopherol
Autor: Daisuke Anegawa, Yuki Sugiura, Yuta Matsuoka, Masamitsu Sone, Mototada Shichiri, Reo Otsuka, Noriko Ishida, Ken-ichi Yamada, Makoto Suematsu, Masayuki Miura, Yoshifumi Yamaguchi
Publikováno v: Communications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
Daisuke Anegawa et al. investigated the mechanisms responsible for cold resistance in the Syrian hamster’s hepatocytes, which exhibited remarkable resistance to prolonged cold culture. Their results suggest that hepatocytes exhibit diet-dependent r
Externí odkaz: https://doaj.org/article/5490d4cebb014a8388a70e5323d72017
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7
Akademický článek
Connexin 30 deficiency attenuates A2 astrocyte responses and induces severe neurodegeneration in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride Parkinson’s disease animal model
Autor: Atsushi Fujita, Hiroo Yamaguchi, Ryo Yamasaki, Yiwen Cui, Yuta Matsuoka, Ken-ichi Yamada, Jun-ichi Kira
Publikováno v: Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-20 (2018)
Abstract Background The first pathology observed in Parkinson’s disease (PD) is ‘dying back’ of striatal dopaminergic (DA) terminals. Connexin (Cx)30, an astrocytic gap junction protein, is upregulated in the striatum in PD, but its roles in ne
Externí odkaz: https://doaj.org/article/fa59bb76569644a882e0026be274ad9b
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