Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Yuta Hikichi"'
Autor:
Aidan McGraw, Grace Hillmer, Stefania M. Medehincu, Yuta Hikichi, Sophia Gagliardi, Kedhar Narayan, Hasset Tibebe, Dacia Marquez, Lilia Mei Bose, Adleigh Keating, Coco Izumi, Kevin Peese, Samit Joshi, Mark Krystal, Kathleen L. DeCicco-Skinner, Eric O. Freed, Luca Sardo, Taisuke Izumi
Publikováno v:
Viruses, Vol 16, Iss 9, p 1423 (2024)
HIV-1 virion maturation is an essential step in the viral replication cycle to produce infectious virus particles. Gag and Gag-Pol polyproteins are assembled at the plasma membrane of the virus-producer cells and bud from it to the extracellular comp
Externí odkaz:
https://doaj.org/article/80d24a174b6e4afea42006719a85adfb
Impaired protective role of HLA-B*57:01/58:01 in HIV-1 CRF01_AE infection: a cohort study in Vietnam
Autor:
Tam Tran Thi Minh, Yuta Hikichi, Shoji Miki, Yuriko Imanari, Shigeru Kusagawa, Midori Okazaki, Thao Dang Thi Thu, Teiichiro Shiino, Saori Matsuoka, Hiroyuki Yamamoto, Jun Ohashi, William W. Hall, Tetsuro Matano, Lan Anh Nguyen Thi, Ai Kawana-Tachikawa
Publikováno v:
International Journal of Infectious Diseases, Vol 128, Iss , Pp 20-31 (2023)
Objectives: Human Leukocyte Antigen HLA-B*57:01 and B*58:01 are considered anti-HIV-1 protective alleles. HLA-B*57:01/58:01-restricted HIV-1 Gag TW10 (TSTLQEQIGW, Gag residues 240-249) epitope-specific CD8+ T cell responses that frequently select for
Externí odkaz:
https://doaj.org/article/feb4aef71d304190b62b7e15524daa2e
Autor:
Yuta Hikichi, Rachel Van Duyne, Phuong Pham, Jennifer L. Groebner, Ann Wiegand, John W. Mellors, Mary F. Kearney, Eric O. Freed
Publikováno v:
mBio, Vol 12, Iss 1 (2021)
Although combination antiretroviral (ARV) therapy is highly effective in controlling the progression of HIV disease, drug resistance can be a major obstacle. Recent findings suggest that resistance can develop without ARV target gene mutations.
Externí odkaz:
https://doaj.org/article/a4bd72fa01324caca28f6cbce9932f14
Autor:
Yuta Hikichi1, Grover, Jonathan R.2, Schäfer, Alicia2, Mothes, Walther2, Freed, Eric O.1 efreed@mail.nih.gov
Publikováno v:
Science Advances. 3/1/2024, Vol. 10 Issue 9, p1-20. 20p.
Publikováno v:
Virology. 532:97-107
The matrix (MA) domain of HIV-1 Gag directs membrane binding of the Gag precursor polyprotein during the late events of virus replication. However, the effects of alteration in Gag membrane binding early post-infection are not well understood. To inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71de044f7b7cc2a79137b836bae54485
https://doi.org/10.1016/j.virol.2019.04.013
https://doi.org/10.1016/j.virol.2019.04.013
Autor:
Ann Wiegand, Phuong Pham, Mary F. Kearney, Rachel Van Duyne, Eric O. Freed, Yuta Hikichi, Jennifer L. Groebner, John W. Mellors
Publikováno v:
mBio, Vol 12, Iss 1 (2021)
mBio
mBio
Although combination antiretroviral (ARV) therapy is highly effective in controlling the progression of HIV disease, drug resistance can be a major obstacle. Recent findings suggest that resistance can develop without ARV target gene mutations.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed77ffda97de7ac2a51cc6ac60b18020
https://doi.org/10.1128/mbio.03134-20
https://doi.org/10.1128/mbio.03134-20
Autor:
Eric O. Freed, Yuta Hikichi
Publikováno v:
Science
Gag – the main structural protein of HIV-1 – is recruited to the plasma membrane for virus assembly by its matrix (MA) domain. Gag is subsequently cleaved into its component domains, causing structural maturation to repurpose the virion for cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bc0c1aa92753f913d6f0854326aed6b
https://doi.org/10.1126/science.abj9075
https://doi.org/10.1126/science.abj9075
Autor:
Philip R. Tedbury, Vineet N. KewalRamani, Eric O. Freed, Ioannis Kagiampakis, Mariia Novikova, Eric Barklis, Ayna Alfadhli, Yuta Hikichi
Publikováno v:
J Virol
The matrix (MA) domain of HIV-1 Gag plays key roles in virus assembly by targeting the Gag precursor to the plasma membrane and directing the incorporation of the viral envelope (Env) glycoprotein into virions. The latter function appears to be in pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::367c15c557022f36791cfb00aefca0f1
https://pubmed.ncbi.nlm.nih.gov/31619553
https://pubmed.ncbi.nlm.nih.gov/31619553
Autor:
Sadatake Tomioka, Michikata Kono, Shinji Nakaya, Mitsuhiro Tsue, Yoshiki Nakazawa, Kazuki Sakaki, Minho Choi, Yuta Hikichi
Publikováno v:
Proceedings of the Combustion Institute. 35:2091-2099
This study carried out experiments to investigate the combustion behavior of ethanol at Mach 2.0 and stagnation temperatures between 1800 and 2200 K using a supersonic combustor with a cavity flame holder. The distribution of droplet diameters in fue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d51b9eae48a588f2c2cede11665daa79
https://doi.org/10.1016/j.proci.2014.07.023
https://doi.org/10.1016/j.proci.2014.07.023
Autor:
Shintaro Tanaka, Shinji Nakaya, Osamu Imamura, Yuta Hikichi, Mitsuhiro Tsue, Sadatake Tomioka, Minho Choi, Toshiki Nomura
Publikováno v:
JOURNAL OF THE JAPAN SOCIETY FOR AERONAUTICAL AND SPACE SCIENCES. 61:151-158
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5eea5de6f09dc6fc081994452234c6f7
https://doi.org/10.2322/jjsass.61.151
https://doi.org/10.2322/jjsass.61.151